Usefulness of intraoperative electrical subcortical mapping during surgery for low-grade gliomas located within eloquent brain regions: functional results in a consecutive series of 103 patients

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  • 1 Departments of Neurosurgery, Neurology, and Neuroanesthesiology, Hôpital de la Salpêtrière, Paris; and Department of Neurology, Centre Hospitalier Universitaire de Nancy, France
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Object. Although a growing number of authors currently advocate surgery to treat low-grade gliomas, controversy still persists, especially because of the risk of inducing neurological sequelae when the tumor is located within eloquent brain areas. Many researchers performing preoperative neurofunctional imaging and intraoperative electrophysiological methods have recently reported on the usefulness of cortical functional mapping. Despite the frequent involvement of subcortical structures by these gliomas, very few investigators have specifically raised the subject of fiber tracking. The authors in this report describe the importance of mapping cortical and subcortical functional regions by using intraoperative realtime direct electrical stimulations during resection of low-grade gliomas.

Methods. Between 1996 and 2001, 103 patients harboring a corticosubcortical low-grade glioma in an eloquent area, with no or only mild deficit, had undergone surgery during which intraoperative electrical mapping of functional cortical sites and subcortical pathways was performed throughout the procedure.

Both eloquent cortical areas and corresponding white fibers were systematically detected and preserved, thus defining the resection boundaries. Despite an 80% rate of immediate postoperative neurological worsening, 94% of patients recovered their preoperative status within 3 months—10% even improved—and then returned to a normal socioprofessional life. Eighty percent of resections were classified as total or subtotal based on control magnetic resonance images.

Conclusions. The use of functional mapping of the white matter together with cortical mapping allowed the authors to optimize the benefit/risk ratio of surgery of low-grade glioma invading eloquent regions. Given that preoperative fiber tracking with the aid of neuroimaging is not yet validated, we used intraoperative real-time cortical and subcortical stimulations as a valuable adjunct to the other mapping methods.

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  • 1.

    Alberstone CD, , Skirboll SL, & Benzel EC, et al: Magnetic source imaging and brain surgery: presurgical and intraoperative planning in 26 patients. J Neurosurg 92:7990, 2000 Alberstone CD, Skirboll SL, Benzel EC, et al: Magnetic source imaging and brain surgery: presurgical and intraoperative planning in 26 patients. J Neurosurg 92:79–90, 2000

    • Search Google Scholar
    • Export Citation
  • 2.

    Allison T, , McCarthy G, & Wood CC, et al: Human cortical potentials evoked by stimulation of the median nerve. II. Cytoarchitectonic areas generating short-latency activity. J Neurophysiol 62:694710, 1989 Allison T, McCarthy G, Wood CC, et al: Human cortical potentials evoked by stimulation of the median nerve. II. Cytoarchitectonic areas generating short-latency activity. J Neurophysiol 62:694–710, 1989

    • Search Google Scholar
    • Export Citation
  • 3.

    Apuzzo MLJ: Brain Surgery: Complication Avoidance and Management. New York: Churchill Livingstone, 1993, Vol 1, pp 379390 Apuzzo MLJ: Brain Surgery: Complication Avoidance and Management. New York: Churchill Livingstone, 1993, Vol 1, pp 379–390

    • Search Google Scholar
    • Export Citation
  • 4.

    Atlas SW, , Howard RS II, & Maldjian J, et al: Functional magnetic resonance imaging of regional brain activity in patients with intracerebral gliomas: findings and implications for clinical management. Neurosurgery 38:329338, 1996 Atlas SW, Howard RS II, Maldjian J, et al: Functional magnetic resonance imaging of regional brain activity in patients with intracerebral gliomas: findings and implications for clinical management. Neurosurgery 38:329–338, 1996

    • Search Google Scholar
    • Export Citation
  • 5.

    Babu KS, & Chandy MJ: Reliability of somatosensory evoked potentials in intraoperative localization of the central sulcus in patients with perirolandic mass lesions. Br J Neurosurg 11:411417, 1997 Babu KS, Chandy MJ: Reliability of somatosensory evoked potentials in intraoperative localization of the central sulcus in patients with perirolandic mass lesions. Br J Neurosurg 11:411–417, 1997

    • Search Google Scholar
    • Export Citation
  • 6.

    Berger MS: Functional mapping-guided resection of low-grade gliomas. Clin Neurosurg 42:437452, 1995 Berger MS: Functional mapping-guided resection of low-grade gliomas. Clin Neurosurg 42:437–452, 1995

    • Search Google Scholar
    • Export Citation
  • 7.

    Berger MS: Lesions in functional (“eloquent”) cortex and subcortical white matter. Clin Neurosurg 41:444463, 1994 Berger MS: Lesions in functional (“eloquent”) cortex and subcortical white matter. Clin Neurosurg 41:444–463, 1994

    • Search Google Scholar
    • Export Citation
  • 8.

    Berger MS, , Deliganis AV, & Dobbins JD, et al: The effect of extent of resection on recurrence in patients with low grade cerebral hemisphere gliomas. Cancer 74:17841791, 1994 Berger MS, Deliganis AV, Dobbins JD, et al: The effect of extent of resection on recurrence in patients with low grade cerebral hemisphere gliomas. Cancer 74:1784–1791, 1994

    • Search Google Scholar
    • Export Citation
  • 9.

    Berger MS, & Ojemann GA: Intraoperative brain mapping techniques in neuro-oncology. Stereotact Funct Neurosurg 58:153161, 1992 Berger MS, Ojemann GA: Intraoperative brain mapping techniques in neuro-oncology. Stereotact Funct Neurosurg 58:153–161, 1992

    • Search Google Scholar
    • Export Citation
  • 10.

    Berger MS, , Ojemann GA, & Lettich E: Neurophysiological monitoring during astrocytoma surgery. Neurosurg Clin N Am 1:6580, 1990 Berger MS, Ojemann GA, Lettich E: Neurophysiological monitoring during astrocytoma surgery. Neurosurg Clin N Am 1:65–80, 1990

    • Search Google Scholar
    • Export Citation
  • 11.

    Berger MS, & Rostomily RC: Low grade gliomas: functional mapping resection strategies, extent of resection, and outcome. J Neurooncol 34:85101, 1997 Berger MS, Rostomily RC: Low grade gliomas: functional mapping resection strategies, extent of resection, and outcome. J Neurooncol 34:85–101, 1997

    • Search Google Scholar
    • Export Citation
  • 12.

    Bittar RG, , Olivier A, & Sadikot AF, et al: Localization of somatosensory function by using positron emission tomography scanning: a comparison with intraoperative cortical stimulation. J Neurosurg 90:478483, 1999 Bittar RG, Olivier A, Sadikot AF, et al: Localization of somatosensory function by using positron emission tomography scanning: a comparison with intraoperative cortical stimulation. J Neurosurg 90:478–483, 1999

    • Search Google Scholar
    • Export Citation
  • 13.

    Black PM, & Ronner SF: Cortical mapping for defining the limits of tumor resection. Neurosurgery 20:914919, 1987 Black PM, Ronner SF: Cortical mapping for defining the limits of tumor resection. Neurosurgery 20:914–919, 1987

    • Search Google Scholar
    • Export Citation
  • 14.

    Bookheimer SY, , Zeffiro TA, & Blaxton T, et al: A direct comparison of PET activation and electrocortical stimulation mapping for language localization. Neurology 48:10561065, 1997 Bookheimer SY, Zeffiro TA, Blaxton T, et al: A direct comparison of PET activation and electrocortical stimulation mapping for language localization. Neurology 48:1056–1065, 1997

    • Search Google Scholar
    • Export Citation
  • 15.

    Brannen JH, , Badie B, & Moritz CH, et al: Reliability of functional MR imaging with word-generation tasks for mapping Broca's area. AJNR 22:17111718, 2001 Brannen JH, Badie B, Moritz CH, et al: Reliability of functional MR imaging with word-generation tasks for mapping Broca's area. AJNR 22:1711–1718, 2001

    • Search Google Scholar
    • Export Citation
  • 16.

    Braun V, , Dempf S, & Tomczak R, et al: Functional cranial neuronavigation. Direct integration of fMRI and PET data. J Neuroradiol 27:157163, 2000 Braun V, Dempf S, Tomczak R, et al: Functional cranial neuronavigation. Direct integration of fMRI and PET data. J Neuroradiol 27:157–163, 2000

    • Search Google Scholar
    • Export Citation
  • 17.

    Cabantog AM, & Bernstein M: Complications of first craniotomy for intra-axial brain tumour. Can J Neurol Sci 21:213218, 1994 Cabantog AM, Bernstein M: Complications of first craniotomy for intra-axial brain tumour. Can J Neurol Sci 21:213–218, 1994

    • Search Google Scholar
    • Export Citation
  • 18.

    Cedzich C, , Taniguchi M, & Schäfer S, et al: Somatosensory evoked potential phase reversal and direct motor cortex stimulation during surgery in and around the central region. Neurosurgery 38:962970, 1996 Cedzich C, Taniguchi M, Schäfer S, et al: Somatosensory evoked potential phase reversal and direct motor cortex stimulation during surgery in and around the central region. Neurosurgery 38:962–970, 1996

    • Search Google Scholar
    • Export Citation
  • 19.

    Chabrerie A, , Nabavi A, & Ozlen F, et al: Three-dimensional reconstruction for cortical surgery: the Brigham and Women's Hospital experience, in Loftus CM, & Batjer HH (eds): Techniques in Neurosurgery. Philadelphia: Lippincott Williams & Wilkins, 2001, Vol 7, pp 6169 Chabrerie A, Nabavi A, Ozlen F, et al: Three-dimensional reconstruction for cortical surgery: the Brigham and Women's Hospital experience, in Loftus CM, Batjer HH (eds): Techniques in Neurosurgery. Philadelphia: Lippincott Williams & Wilkins, 2001, Vol 7, pp 61–69

    • Search Google Scholar
    • Export Citation
  • 20.

    Coenen VA, , Krings T, & Mayfrank L, et al: Three-dimensional visualization of the pyramidal tract in a neuronavigation system during brain tumor surgery: first experiences and technical note. Neurosurgery 49:8693, 2001 Coenen VA, Krings T, Mayfrank L, et al: Three-dimensional visualization of the pyramidal tract in a neuronavigation system during brain tumor surgery: first experiences and technical note. Neurosurgery 49:86–93, 2001

    • Search Google Scholar
    • Export Citation
  • 21.

    Conturo TE, , Lori NF, & Cull TS, et al: Tracking neuronal fiber pathways in the living human brain. Proc Natl Acad Sci USA 96:1042210427, 1999 Conturo TE, Lori NF, Cull TS, et al: Tracking neuronal fiber pathways in the living human brain. Proc Natl Acad Sci USA 96:10422–10427, 1999

    • Search Google Scholar
    • Export Citation
  • 22.

    Cote R, , Battista RN, & Wolfson C, et al: The Canadian Neurological Scale: validation and reliability assessment. Neurology 39:638643, 1989 Cote R, Battista RN, Wolfson C, et al: The Canadian Neurological Scale: validation and reliability assessment. Neurology 39:638–643, 1989

    • Search Google Scholar
    • Export Citation
  • 23.

    Couldwell WT, & Yong VW: Glioma invasion. J Neurosurg 95:379380, 2001 Couldwell WT, Yong VW: Glioma invasion. J Neurosurg 95:379–380, 2001

    • Search Google Scholar
    • Export Citation
  • 24.

    Cukiert A, , Gronich G, & Marino R Jr: Surgical approaches to tumors and epileptogenic zones close to Wernicke's area. Arq Neuropsiquiatr 53:587591, 1995 Cukiert A, Gronich G, Marino R Jr: Surgical approaches to tumors and epileptogenic zones close to Wernicke's area. Arq Neuropsiquiatr 53:587–591, 1995

    • Search Google Scholar
    • Export Citation
  • 25.

    Danks RA, , Aglio LS, & Gugino LD, et al: Craniotomy under local anesthesia and monitored conscious sedation for the resection of tumors involving eloquent cortex. J Neurooncol 49:131139, 2000 Danks RA, Aglio LS, Gugino LD, et al: Craniotomy under local anesthesia and monitored conscious sedation for the resection of tumors involving eloquent cortex. J Neurooncol 49:131–139, 2000

    • Search Google Scholar
    • Export Citation
  • 26.

    Danks RA, , Rogers M, & Aglio LS, et al: Patient tolerance of craniotomy performed with the patient under local anesthesia and monitored conscious sedation. Neurosurgery 42:2836, 1998 Danks RA, Rogers M, Aglio LS, et al: Patient tolerance of craniotomy performed with the patient under local anesthesia and monitored conscious sedation. Neurosurgery 42:28–36, 1998

    • Search Google Scholar
    • Export Citation
  • 27.

    Duffau H: Acute functional reorganisation of the human motor cortex during resection of central lesions: a study using intraoperative brain mapping. J Neurol Neurosurg Psychiatry 70:506513, 2001 Duffau H: Acute functional reorganisation of the human motor cortex during resection of central lesions: a study using intraoperative brain mapping. J Neurol Neurosurg Psychiatry 70:506–513, 2001

    • Search Google Scholar
    • Export Citation
  • 28.

    Duffau H: Intraoperative direct subcortical stimulation for identification of the internal capsule, combined with an image-guided stereotactic system during surgery for basal ganglia lesions. Surg Neurol 53:250254, 2000 Duffau H: Intraoperative direct subcortical stimulation for identification of the internal capsule, combined with an image-guided stereotactic system during surgery for basal ganglia lesions. Surg Neurol 53:250–254, 2000

    • Search Google Scholar
    • Export Citation
  • 29.

    Duffau H: Recovery from complete hemiplegia following resection of a retrocentral metastasis: the prognostic value of intraoperative cortical stimulations. Case report. J Neurosurg 95:10501052, 2001 Duffau H: Recovery from complete hemiplegia following resection of a retrocentral metastasis: the prognostic value of intraoperative cortical stimulations. Case report. J Neurosurg 95:1050–1052, 2001

    • Search Google Scholar
    • Export Citation
  • 30.

    Duffau H, , Bauchet L, & Lehéricy S, et al: Functional compensation of the left dominant insula for language. Neuroreport 12:21592163, 2001 Duffau H, Bauchet L, Lehéricy S, et al: Functional compensation of the left dominant insula for language. Neuroreport 12:2159–2163, 2001

    • Search Google Scholar
    • Export Citation
  • 31.

    Duffau H, , Capelle L, & Lopes M, et al: The insular lobe: physiopathological and surgical considerations. Neurosurgery 47:801811, 2000 Duffau H, Capelle L, Lopes M, et al: The insular lobe: physiopathological and surgical considerations. Neurosurgery 47:801–811, 2000

    • Search Google Scholar
    • Export Citation
  • 32.

    Duffau H, , Capelle L, & Lopes M, et al: Medically intractable epilepsy from insular low-grade gliomas: improvement after an extended lesionectomy. Acta Neurochir 144:563573, 2002 Duffau H, Capelle L, Lopes M, et al: Medically intractable epilepsy from insular low-grade gliomas: improvement after an extended lesionectomy. Acta Neurochir 144:563–573, 2002

    • Search Google Scholar
    • Export Citation
  • 33.

    Duffau H, , Capelle L, & Sichez J, et al: Intra-operative direct electrical stimulations of the central nervous system: the Salpêtrière experience with 60 patients. Acta Neurochir 141:11571167, 1999 Duffau H, Capelle L, Sichez J, et al: Intra-operative direct electrical stimulations of the central nervous system: the Salpêtrière experience with 60 patients. Acta Neurochir 141:1157–1167, 1999

    • Search Google Scholar
    • Export Citation
  • 34.

    Duffau H, , Capelle L, & Sichez N, et al: Intraoperative mapping of the subcortical language pathways using direct stimulations. An anatomo-functional study. Brain 125:199214, 2002 Duffau H, Capelle L, Sichez N, et al: Intraoperative mapping of the subcortical language pathways using direct stimulations. An anatomo-functional study. Brain 125:199–214, 2002

    • Search Google Scholar
    • Export Citation
  • 35.

    Duffau H, , Denvil D, & Capelle L: Absence of movement disorders after surgical resection of glioma invading the right striatum. J Neurosurg 97:363369, 2002 Duffau H, Denvil D, Capelle L: Absence of movement disorders after surgical resection of glioma invading the right striatum. J Neurosurg 97:363–369, 2002

    • Search Google Scholar
    • Export Citation
  • 36.

    Duffau H, , Lopes M, & Denvil D, et al: Delayed onset of supplementary motor area syndrome after surgical resection of the mesial frontal lobe: a time course study using intraoperative mapping in an awake patient. Stereotact Funct Neurosurg 76:7482, 2001 Duffau H, Lopes M, Denvil D, et al: Delayed onset of supplementary motor area syndrome after surgical resection of the mesial frontal lobe: a time course study using intraoperative mapping in an awake patient. Stereotact Funct Neurosurg 76:74–82, 2001

    • Search Google Scholar
    • Export Citation
  • 37.

    Ebel H, , Ebel M, & Schillinger G, et al: Surgery of intrinsic cerebral neoplasms in eloquent areas under local anesthesia. Minim Invasive Neurosurg 43:192196, 2000 Ebel H, Ebel M, Schillinger G, et al: Surgery of intrinsic cerebral neoplasms in eloquent areas under local anesthesia. Minim Invasive Neurosurg 43:192–196, 2000

    • Search Google Scholar
    • Export Citation
  • 38.

    Ebeling U, , Schmid UD, & Ying H, et al: Safe surgery of lesions near the motor cortex using intra-operative mapping techniques: a report on 50 patients. Acta Neurochir 119:2328, 1992 Ebeling U, Schmid UD, Ying H, et al: Safe surgery of lesions near the motor cortex using intra-operative mapping techniques: a report on 50 patients. Acta Neurochir 119:23–28, 1992

    • Search Google Scholar
    • Export Citation
  • 39.

    Eisner W, , Burtscher J, & Bale R, et al: Use of neuronavigation and electrophysiology in surgery of subcortically located lesions in the sensorimotor strip. J Neurol Neurosurg Psychiatry 72:378381, 2002 Eisner W, Burtscher J, Bale R, et al: Use of neuronavigation and electrophysiology in surgery of subcortically located lesions in the sensorimotor strip. J Neurol Neurosurg Psychiatry 72:378–381, 2002

    • Search Google Scholar
    • Export Citation
  • 40.

    Fadul C, , Wood J, & Thaler H, et al: Morbidity and mortality of craniotomy for excision of supratentorial gliomas. Neurology 38:13741379, 1988 Fadul C, Wood J, Thaler H, et al: Morbidity and mortality of craniotomy for excision of supratentorial gliomas. Neurology 38:1374–1379, 1988

    • Search Google Scholar
    • Export Citation
  • 41.

    Fandino J, , Kollias SS, & Wieser HG, et al: Intraoperative validation of functional magnetic resonance imaging and cortical reorganization patterns in patients with brain tumors involving the primary motor cortex. J Neurosurg 91:238250, 1999 Fandino J, Kollias SS, Wieser HG, et al: Intraoperative validation of functional magnetic resonance imaging and cortical reorganization patterns in patients with brain tumors involving the primary motor cortex. J Neurosurg 91:238–250, 1999

    • Search Google Scholar
    • Export Citation
  • 42.

    FitzGerald DB, , Cosgrove GR, & Ronner S, et al: Location of language in the cortex: a comparison between functional MR imaging and electrocortical stimulation. AJNR 18:15291539, 1997 FitzGerald DB, Cosgrove GR, Ronner S, et al: Location of language in the cortex: a comparison between functional MR imaging and electrocortical stimulation. AJNR 18:1529–1539, 1997

    • Search Google Scholar
    • Export Citation
  • 43.

    Fontaine D, , Capelle L, & Duffau H: Somatotopy of the supplementary motor area: evidence by correlation of the extent of surgical resection with the clinical patterns of deficit. Neurosurgery 50:297305, 2002 Fontaine D, Capelle L, Duffau H: Somatotopy of the supplementary motor area: evidence by correlation of the extent of surgical resection with the clinical patterns of deficit. Neurosurgery 50:297–305, 2002

    • Search Google Scholar
    • Export Citation
  • 44.

    Fried I, , Nenov VI, & Ojemann SG, et al: Functional MR and PET imaging of rolandic and visual cortices for neurosurgical planning. J Neurosurg 83:854861, 1995 Fried I, Nenov VI, Ojemann SG, et al: Functional MR and PET imaging of rolandic and visual cortices for neurosurgical planning. J Neurosurg 83:854–861, 1995

    • Search Google Scholar
    • Export Citation
  • 45.

    Gallen CC, , Schwartz BJ, & Bucholz RD, et al: Presurgical localization of functional cortex using magnetic source imaging. J Neurosurg 82:988994, 1995 Gallen CC, Schwartz BJ, Bucholz RD, et al: Presurgical localization of functional cortex using magnetic source imaging. J Neurosurg 82:988–994, 1995

    • Search Google Scholar
    • Export Citation
  • 46.

    Gallen CC, , Sobel DF, & Waltz T, et al: Noninvasive presurgical neuromagnetic mapping of somatosensory cortex. Neurosurgery 33:260268, 1993 Gallen CC, Sobel DF, Waltz T, et al: Noninvasive presurgical neuromagnetic mapping of somatosensory cortex. Neurosurgery 33:260–268, 1993

    • Search Google Scholar
    • Export Citation
  • 47.

    Ganslandt O, , Fahlbusch R, & Nimsky C, et al: Functional neuronavigation with magnetoencephalography: outcome in 50 patients with lesions around the motor cortex. J Neurosurg 91:7379, 1999 Ganslandt O, Fahlbusch R, Nimsky C, et al: Functional neuronavigation with magnetoencephalography: outcome in 50 patients with lesions around the motor cortex. J Neurosurg 91:73–79, 1999

    • Search Google Scholar
    • Export Citation
  • 48.

    Ganslandt O, , Steinmeier R, & Kober H, et al: Magnetic source imaging combined with image-guided frameless stereotaxy: a new method in surgery around the motor strip. Neurosurgery 41:621628, 1997 Ganslandt O, Steinmeier R, Kober H, et al: Magnetic source imaging combined with image-guided frameless stereotaxy: a new method in surgery around the motor strip. Neurosurgery 41:621–628, 1997

    • Search Google Scholar
    • Export Citation
  • 49.

    Giese A, & Westphal M: Glioma invasion in the central nervous system. Neurosurgery 39:235250, 1996 Giese A, Westphal M: Glioma invasion in the central nervous system. Neurosurgery 39:235–250, 1996

    • Search Google Scholar
    • Export Citation
  • 50.

    Gossl C, , Fahrmeir L, & Putz B, et al: Fiber tracking from DTI using linear state space models: detectability of the pyramidal tract. Neuroimage 16:378388, 2002 Gossl C, Fahrmeir L, Putz B, et al: Fiber tracking from DTI using linear state space models: detectability of the pyramidal tract. Neuroimage 16:378–388, 2002

    • Search Google Scholar
    • Export Citation
  • 51.

    Haglund MM, & Berger M: Functional mapping of motor sensory, and language pathways during low-grade glioma removal. Tech Neurosurg 2:141149, 1996 Haglund MM, Berger M: Functional mapping of motor sensory, and language pathways during low-grade glioma removal. Tech Neurosurg 2:141–149, 1996

    • Search Google Scholar
    • Export Citation
  • 52.

    Haglund MM, , Berger MS, & Shamseldin M, et al: Cortical localization of temporal lobe language sites in patients with gliomas. Neurosurgery 34:567576, 1994 Haglund MM, Berger MS, Shamseldin M, et al: Cortical localization of temporal lobe language sites in patients with gliomas. Neurosurgery 34:567–576, 1994

    • Search Google Scholar
    • Export Citation
  • 53.

    Harris AJ: Harris Test of Lateral Dominance. Manual of Directions for Administration and Interpretation. New York: Psychological Corporation, 1947 Harris AJ: Harris Test of Lateral Dominance. Manual of Directions for Administration and Interpretation. New York: Psychological Corporation, 1947

    • Search Google Scholar
    • Export Citation
  • 54.

    Helmers SL: Evoked potentials for cortical mapping in children and adults, in Loftus CM, & Batjer HH (eds): Techniques in Neurosurgery. Philadelphia: Lippincott Williams & Wilkins, 2001, Vol 7, pp 411 Helmers SL: Evoked potentials for cortical mapping in children and adults, in Loftus CM, Batjer HH (eds): Techniques in Neurosurgery. Philadelphia: Lippincott Williams & Wilkins, 2001, Vol 7, pp 4–11

    • Search Google Scholar
    • Export Citation
  • 55.

    Herholz K, , Reulen HJ, & von Stockhausen HM, et al: Preoperative activation and intraoperative stimulation of language-related areas in patients with glioma. Neurosurgery 41:12531262, 1997 Herholz K, Reulen HJ, von Stockhausen HM, et al: Preoperative activation and intraoperative stimulation of language-related areas in patients with glioma. Neurosurgery 41:1253–1262, 1997

    • Search Google Scholar
    • Export Citation
  • 56.

    Hill DL, , Maurer CR Jr, & Maciunas RJ, et al: Measurement of intraoperative brain surface deformation under a craniotomy. Neurosurgery 43:514528, 1998 Hill DL, Maurer CR Jr, Maciunas RJ, et al: Measurement of intraoperative brain surface deformation under a craniotomy. Neurosurgery 43:514–528, 1998

    • Search Google Scholar
    • Export Citation
  • 57.

    Hill DLG, , Smith AD, & Simmons A, et al: Sources of error in comparing functional magnetic resonance imaging and invasive electrophysiological recordings. J Neurosurg 93:214223, 2000 Hill DLG, Smith AD, Simmons A, et al: Sources of error in comparing functional magnetic resonance imaging and invasive electrophysiological recordings. J Neurosurg 93:214–223, 2000

    • Search Google Scholar
    • Export Citation
  • 58.

    Hirsch J, , Ruge MI, & Kim KHS, et al: An integrated functional magnetic resonance imaging procedure for preoperative mapping of cortical areas associated with tactile, motor, language, and visual functions. Neurosurgery 47:711722, 2000 Hirsch J, Ruge MI, Kim KHS, et al: An integrated functional magnetic resonance imaging procedure for preoperative mapping of cortical areas associated with tactile, motor, language, and visual functions. Neurosurgery 47:711–722, 2000

    • Search Google Scholar
    • Export Citation
  • 59.

    Holodny AI, , Schwartz TH, & Ollenschleger M, et al: Tumor involvement of the corticospinal tract: diffusion magnetic resonance tractography with intraoperative correlation. Case illustration. J Neurosurg 95:1082, 2001 Holodny AI, Schwartz TH, Ollenschleger M, et al: Tumor involvement of the corticospinal tract: diffusion magnetic resonance tractography with intraoperative correlation. Case illustration. J Neurosurg 95:1082, 2001

    • Search Google Scholar
    • Export Citation
  • 60.

    Horstmann GA, , Talies S, & Westermann B, et al: Microstereometrically guided cortical stimulation for the intraoperative identification of the central motor strip. Stereotact Funct Neurosurg 65:130135, 1995 Horstmann GA, Talies S, Westermann B, et al: Microstereometrically guided cortical stimulation for the intraoperative identification of the central motor strip. Stereotact Funct Neurosurg 65:130–135, 1995

    • Search Google Scholar
    • Export Citation
  • 61.

    Hund M, , Rezai AR, & Kronberg E, et al: Magnetoencephalographic mapping: basis of a new functional risk profile in the selection of patients with cortical brain lesions. Neurosurgery 40:936943, 1997 Hund M, Rezai AR, Kronberg E, et al: Magnetoencephalographic mapping: basis of a new functional risk profile in the selection of patients with cortical brain lesions. Neurosurgery 40:936–943, 1997

    • Search Google Scholar
    • Export Citation
  • 62.

    Inoue T, , Shimizu H, & Nakasato N, et al: Accuracy and limitation of functional magnetic resonance imaging for identification of the central sulcus: comparison with magnetoencephalography in patients with brain tumors. Neuroimage 10:738748, 1999 Inoue T, Shimizu H, Nakasato N, et al: Accuracy and limitation of functional magnetic resonance imaging for identification of the central sulcus: comparison with magnetoencephalography in patients with brain tumors. Neuroimage 10:738–748, 1999

    • Search Google Scholar
    • Export Citation
  • 63.

    Inoue T, , Shimizu H, & Yoshimoto T: Imaging the pyramidal tracts in patients with brain tumors. Clin Neurol Neurosurg 101:410, 1999 Inoue T, Shimizu H, Yoshimoto T: Imaging the pyramidal tracts in patients with brain tumors. Clin Neurol Neurosurg 101:4–10, 1999

    • Search Google Scholar
    • Export Citation
  • 64.

    Karnofsky DA, & Burchenal JH: The clinical evaluation of chemotherapeutic agents in cancer, in MacLeod CM (ed): Evaluation of Chemotherapeutic Agents. New York: Columbia University Press, 1949, pp 191205 Karnofsky DA, Burchenal JH: The clinical evaluation of chemotherapeutic agents in cancer, in MacLeod CM (ed): Evaluation of Chemotherapeutic Agents. New York: Columbia University Press, 1949, pp 191–205

    • Search Google Scholar
    • Export Citation
  • 65.

    Keles GE, , Lamborn KR, & Berger MS: Low-grade hemispheric gliomas in adults: a critical review of extent of resection as a factor influencing outcome. J Neurosurg 95:735745, 2001 Keles GE, Lamborn KR, Berger MS: Low-grade hemispheric gliomas in adults: a critical review of extent of resection as a factor influencing outcome. J Neurosurg 95:735–745, 2001

    • Search Google Scholar
    • Export Citation
  • 66.

    King RB, & Schell GR: Cortical localization and monitoring during cerebral operations. J Neurosurg 67:210219, 1987 King RB, Schell GR: Cortical localization and monitoring during cerebral operations. J Neurosurg 67:210–219, 1987

    • Search Google Scholar
    • Export Citation
  • 67.

    Kober H, , Möller M, & Nimsky C, et al: New approach to localize speech relevant brain areas and hemispheric dominance using spatially filtered magnetoencephalography. Hum Brain Mapp 14:236250, 2001 Kober H, Möller M, Nimsky C, et al: New approach to localize speech relevant brain areas and hemispheric dominance using spatially filtered magnetoencephalography. Hum Brain Mapp 14:236–250, 2001

    • Search Google Scholar
    • Export Citation
  • 68.

    Kombos T, , Suess O, & Ciklatekerlio O, et al: Monitoring of intraoperative motor evoked potentials to increase the safety of surgery in and around the motor cortex. J Neurosurg 95:608614, 2001 Kombos T, Suess O, Ciklatekerlio O, et al: Monitoring of intraoperative motor evoked potentials to increase the safety of surgery in and around the motor cortex. J Neurosurg 95:608–614, 2001

    • Search Google Scholar
    • Export Citation
  • 69.

    Kombos T, , Suess O, & Funk T, et al: Intra-operative mapping of the motor cortex during surgery in and around the motor cortex. Acta Neurochir 142:263268, 2000 Kombos T, Suess O, Funk T, et al: Intra-operative mapping of the motor cortex during surgery in and around the motor cortex. Acta Neurochir 142:263–268, 2000

    • Search Google Scholar
    • Export Citation
  • 70.

    Krainik A, , Lehéricy S, & Duffau H, et al: Role of the supplementary motor area in motor deficit following medial frontal lobe surgery. Neurology 57:871878, 2001 Krainik A, Lehéricy S, Duffau H, et al: Role of the supplementary motor area in motor deficit following medial frontal lobe surgery. Neurology 57:871–878, 2001

    • Search Google Scholar
    • Export Citation
  • 71.

    Krings T, , Schreckenberger M, & Rohde V, et al: Metabolic and electrophysiological validation of functional MRI. J Neurol Neurosurg Psychiatry 71:762771, 2001 Krings T, Schreckenberger M, Rohde V, et al: Metabolic and electrophysiological validation of functional MRI. J Neurol Neurosurg Psychiatry 71:762–771, 2001

    • Search Google Scholar
    • Export Citation
  • 72.

    Krombach GA, , Spetzger U, & Rohde V, et al: Intraoperative localization of functional regions in the sensorimotor cortex by neuronavigation and cortical mapping. Comput Aided Surg 3:6473, 1998 Krombach GA, Spetzger U, Rohde V, et al: Intraoperative localization of functional regions in the sensorimotor cortex by neuronavigation and cortical mapping. Comput Aided Surg 3:64–73, 1998

    • Search Google Scholar
    • Export Citation
  • 73.

    Lang FF, , Olansen NE, & DeMonte F, et al: Surgical resection of intrinsic insular tumors: complication avoidance. J Neurosurg 95:638650, 2001 Lang FF, Olansen NE, DeMonte F, et al: Surgical resection of intrinsic insular tumors: complication avoidance. J Neurosurg 95:638–650, 2001

    • Search Google Scholar
    • Export Citation
  • 74.

    Le Bihan D, , Mangin JF, & Poupon C, et al: Diffusion tensor imaging: concepts and applications. J Magn Reson Imaging 13:534546, 2001 Le Bihan D, Mangin JF, Poupon C, et al: Diffusion tensor imaging: concepts and applications. J Magn Reson Imaging 13:534–546, 2001

    • Search Google Scholar
    • Export Citation
  • 75.

    Lee CC, , Ward HA, & Sharbrough FW, et al: Assessment of functional MR imaging in neurosurgical planning. AJNR 20:15111519, 1999 Lee CC, Ward HA, Sharbrough FW, et al: Assessment of functional MR imaging in neurosurgical planning. AJNR 20:1511–1519, 1999

    • Search Google Scholar
    • Export Citation
  • 76.

    Lehéricy S, , Cohen L, & Bazin B, et al: Functional MR evaluation of temporal and frontal language dominance compared with the Wada test. Neurology 54:16251633, 2000 Lehéricy S, Cohen L, Bazin B, et al: Functional MR evaluation of temporal and frontal language dominance compared with the Wada test. Neurology 54:1625–1633, 2000

    • Search Google Scholar
    • Export Citation
  • 77.

    Lehéricy S, , Duffau H, & Cornu P, et al: Correspondence between functional magnetic resonance imaging somatotopy and individual brain anatomy of the central region: comparison with intraoperative stimulation in patients with brain tumors. J Neurosurg 92:589598, 2000 Lehéricy S, Duffau H, Cornu P, et al: Correspondence between functional magnetic resonance imaging somatotopy and individual brain anatomy of the central region: comparison with intraoperative stimulation in patients with brain tumors. J Neurosurg 92:589–598, 2000

    • Search Google Scholar
    • Export Citation
  • 78.

    Lüders H, , Lesser RP, & Dinner DS, et al: Localization of cortical function: new information from extraoperative monitoring of patients with epilepsy. Epilepsia 29 (Suppl 2):S56S65, 1988 Lüders H, Lesser RP, Dinner DS, et al: Localization of cortical function: new information from extraoperative monitoring of patients with epilepsy. Epilepsia 29 (Suppl 2):S56–S65, 1988

    • Search Google Scholar
    • Export Citation
  • 79.

    Lurito JT, , Lowe MJ, & Sartorius C, et al: Comparison of fMRI and intraoperative direct cortical stimulation in localization of receptive language areas. J Comput Assist Tomogr 24:99105, 2000 Lurito JT, Lowe MJ, Sartorius C, et al: Comparison of fMRI and intraoperative direct cortical stimulation in localization of receptive language areas. J Comput Assist Tomogr 24:99–105, 2000

    • Search Google Scholar
    • Export Citation
  • 80.

    Makela JP, , Kirveskari E, & Seppa M, et al: Three-dimensional integration of brain anatomy and function to facilitate intraoperative navigation around the sensorimotor strip. Hum Brain Mapp 12:180192, 2001 Makela JP, Kirveskari E, Seppa M, et al: Three-dimensional integration of brain anatomy and function to facilitate intraoperative navigation around the sensorimotor strip. Hum Brain Mapp 12:180–192, 2001

    • Search Google Scholar
    • Export Citation
  • 81.

    Matz PG, , Cobbs C, & Berger MS: Intraoperative cortical mapping as a guide to the surgical resection of gliomas. J Neurooncol 42:233245, 1999 Matz PG, Cobbs C, Berger MS: Intraoperative cortical mapping as a guide to the surgical resection of gliomas. J Neurooncol 42:233–245, 1999

    • Search Google Scholar
    • Export Citation
  • 82.

    McCarthy G, , Allison T, & Spencer DD: Localization of the face area of human sensorimotor cortex by intracranial recording of somatosensory evoked potentials. J Neurosurg 79:874884, 1993 McCarthy G, Allison T, Spencer DD: Localization of the face area of human sensorimotor cortex by intracranial recording of somatosensory evoked potentials. J Neurosurg 79:874–884, 1993

    • Search Google Scholar
    • Export Citation
  • 83.

    McCormack BM, , Miller DC, & Budzilovich GN, et al: Treatment and survival of low-grade astrocytoma in adults—1977–1988. Neurosurgery 31:636642, 1992 McCormack BM, Miller DC, Budzilovich GN, et al: Treatment and survival of low-grade astrocytoma in adults—1977–1988. Neurosurgery 31:636–642, 1992

    • Search Google Scholar
    • Export Citation
  • 84.

    McDonald JD, , Chong BW, & Lewine JD, et al: Integration of preoperative and intraoperative functional brain mapping in a frameless stereotactic environment for lesions near eloquent cortex. Technical note. J Neurosurg 90:591598, 1999 McDonald JD, Chong BW, Lewine JD, et al: Integration of preoperative and intraoperative functional brain mapping in a frameless stereotactic environment for lesions near eloquent cortex. Technical note. J Neurosurg 90:591–598, 1999

    • Search Google Scholar
    • Export Citation
  • 85.

    Meyer FB, , Bates LM, & Goerss SJ, et al: Awake craniotomy for aggressive resection of primary gliomas located in eloquent brain. Mayo Clin Proc 76:677687, 2001 Meyer FB, Bates LM, Goerss SJ, et al: Awake craniotomy for aggressive resection of primary gliomas located in eloquent brain. Mayo Clin Proc 76:677–687, 2001

    • Search Google Scholar
    • Export Citation
  • 86.

    Mine S, , Oka N, & Yamaura A, et al: Presurgical functional localization of primary somatosensory cortex by dipole tracing method of scalp-skull-brain head model applied to somatosensory evoked potential. Electroencephalogr Clin Neurophysiol 108:226233, 1998 Mine S, Oka N, Yamaura A, et al: Presurgical functional localization of primary somatosensory cortex by dipole tracing method of scalp-skull-brain head model applied to somatosensory evoked potential. Electroencephalogr Clin Neurophysiol 108:226–233, 1998

    • Search Google Scholar
    • Export Citation
  • 87.

    Morioka T, , Shigeto H, & Ishibashi H, et al: Magnetic source imaging of the sensory cortex on the surface anatomy MR scanning. Neurol Res 20:235241, 1998 Morioka T, Shigeto H, Ishibashi H, et al: Magnetic source imaging of the sensory cortex on the surface anatomy MR scanning. Neurol Res 20:235–241, 1998

    • Search Google Scholar
    • Export Citation
  • 88.

    Morris HH III, , Lüders H, & Hahn JF, et al: Neurophysiological techniques as an aid to surgical treatment of primary brain tumors. Ann Neurol 19:559567, 1986 Morris HH III, Lüders H, Hahn JF, et al: Neurophysiological techniques as an aid to surgical treatment of primary brain tumors. Ann Neurol 19:559–567, 1986

    • Search Google Scholar
    • Export Citation
  • 89.

    Mueller WM, , Yetkin FZ, & Hammeke TA, et al: Functional magnetic resonance imaging mapping of the motor cortex in patients with cerebral tumors. Neurosurgery 39:515521, 1996 Mueller WM, Yetkin FZ, Hammeke TA, et al: Functional magnetic resonance imaging mapping of the motor cortex in patients with cerebral tumors. Neurosurgery 39:515–521, 1996

    • Search Google Scholar
    • Export Citation
  • 90.

    Nakada T, , Nakayama N, & Fujii Y, et al: Clinical application of three-dimensional anisotropy contrast magnetic resonance axonography. Technical note. J Neurosurg 90:791795, 1999 Nakada T, Nakayama N, Fujii Y, et al: Clinical application of three-dimensional anisotropy contrast magnetic resonance axonography. Technical note. J Neurosurg 90:791–795, 1999

    • Search Google Scholar
    • Export Citation
  • 91.

    Nakamura M, , Konishi N, & Tsunoda S, et al: Analysis of prognostic and survival factors related to treatment of low-grade astrocytoma in adults. Oncology 58:108116, 2000 Nakamura M, Konishi N, Tsunoda S, et al: Analysis of prognostic and survival factors related to treatment of low-grade astrocytoma in adults. Oncology 58:108–116, 2000

    • Search Google Scholar
    • Export Citation
  • 92.

    Nariai T, , Senda M, & Ishii K, et al: Three-dimensional imaging of cortical structure, function and glioma for tumor resection. J Nucl Med 38:15631568, 1997 Nariai T, Senda M, Ishii K, et al: Three-dimensional imaging of cortical structure, function and glioma for tumor resection. J Nucl Med 38:1563–1568, 1997

    • Search Google Scholar
    • Export Citation
  • 93.

    Nikas DC, , Bello L, & Zamani AA, et al: Neurosurgical considerations in supratentorial low-grade gliomas: experience with 175 patients. Neurosurg Focus 4 (4):Article 4, 1998 Nikas DC, Bello L, Zamani AA, et al: Neurosurgical considerations in supratentorial low-grade gliomas: experience with 175 patients. Neurosurg Focus 4 (4):Article 4, 1998

    • Search Google Scholar
    • Export Citation
  • 94.

    Nikas DC, , Danks RA, & Black PM: Tumor surgery under local anesthesia, in Loftus CM, & Batjer HH (eds): Techniques in Neurosurgery. Philadelphia: Lippincott Williams & Wilkins, 2001, Vol 7, pp 7084 Nikas DC, Danks RA, Black PM: Tumor surgery under local anesthesia, in Loftus CM, Batjer HH (eds): Techniques in Neurosurgery. Philadelphia: Lippincott Williams & Wilkins, 2001, Vol 7, pp 70–84

    • Search Google Scholar
    • Export Citation
  • 95.

    Nimsky C, , Ganslandt O, & Kober H, et al: Integration of functional magnetic resonance imaging supported by magnetoencephalography in functional neuronavigation. Neurosurgery 44:12491256, 1999 Nimsky C, Ganslandt O, Kober H, et al: Integration of functional magnetic resonance imaging supported by magnetoencephalography in functional neuronavigation. Neurosurgery 44:1249–1256, 1999

    • Search Google Scholar
    • Export Citation
  • 96.

    Nitschke MF, , Melchert UH, & Hahn C, et al: Preoperative functional magnetic resonance imaging (fMRI) of the motor system in patients with tumors in the parietal lobe. Acta Neurochir 140:12231229, 1998 Nitschke MF, Melchert UH, Hahn C, et al: Preoperative functional magnetic resonance imaging (fMRI) of the motor system in patients with tumors in the parietal lobe. Acta Neurochir 140:1223–1229, 1998

    • Search Google Scholar
    • Export Citation
  • 97.

    Ojemann G, , Ojemann J, & Lettich E, et al: Cortical language localization in left, dominant hemisphere. An electrical stimulation mapping investigation in 117 patients. J Neurosurg 71:316326, 1989 Ojemann G, Ojemann J, Lettich E, et al: Cortical language localization in left, dominant hemisphere. An electrical stimulation mapping investigation in 117 patients. J Neurosurg 71:316–326, 1989

    • Search Google Scholar
    • Export Citation
  • 98.

    Ojemann GA: Functional mapping of cortical language areas in adults. Intraoperative approaches. Adv Neurol 63:155163, 1993 Ojemann GA: Functional mapping of cortical language areas in adults. Intraoperative approaches. Adv Neurol 63:155–163, 1993

    • Search Google Scholar
    • Export Citation
  • 99.

    Ojemann JG, , Ojemann GA, & Lettich E: Cortical stimulation mapping of language cortex by using a verb generation task: effects of learning and comparison to mapping based on object naming. J Neurosurg 97:3338, 2002 Ojemann JG, Ojemann GA, Lettich E: Cortical stimulation mapping of language cortex by using a verb generation task: effects of learning and comparison to mapping based on object naming. J Neurosurg 97:33–38, 2002

    • Search Google Scholar
    • Export Citation
  • 100.

    Papanicolaou AC, , Simos PG, & Breier JI, et al: Magnetoencephalographic mapping of the language-specific cortex. J Neurosurg 90:8593, 1999 Papanicolaou AC, Simos PG, Breier JI, et al: Magnetoencephalographic mapping of the language-specific cortex. J Neurosurg 90:85–93, 1999

    • Search Google Scholar
    • Export Citation
  • 101.

    Peraud A, , Ansari H, & Bise K, et al: Clinical outcome of supratentorial astrocytoma WHO grade II. Acta Neurochir 140:12131222, 1998 Peraud A, Ansari H, Bise K, et al: Clinical outcome of supratentorial astrocytoma WHO grade II. Acta Neurochir 140:1213–1222, 1998

    • Search Google Scholar
    • Export Citation
  • 102.

    Peraud A, , Meschede M, & Eisner W, et al: Surgical resection of grade II astrocytomas in the superior frontal gyrus. Neurosurgery 50:966977, 2002 Peraud A, Meschede M, Eisner W, et al: Surgical resection of grade II astrocytomas in the superior frontal gyrus. Neurosurgery 50:966–977, 2002

    • Search Google Scholar
    • Export Citation
  • 103.

    Philippon JH, , Clémenceau SH, & Fauchon FH, et al: Supratentorial low-grade astrocytomas in adults. Neurosurgery 32:554559, 1993 Philippon JH, Clémenceau SH, Fauchon FH, et al: Supratentorial low-grade astrocytomas in adults. Neurosurgery 32:554–559, 1993

    • Search Google Scholar
    • Export Citation
  • 104.

    Piepmeier J, , Christopher S, & Spencer D, et al: Variations in the natural history and survival of patients with supratentorial low-grade astrocytomas. Neurosurgery 38:872879, 1996 Piepmeier J, Christopher S, Spencer D, et al: Variations in the natural history and survival of patients with supratentorial low-grade astrocytomas. Neurosurgery 38:872–879, 1996

    • Search Google Scholar
    • Export Citation
  • 105.

    Pouratian N, , Bookheimer SY, & Rex DE, et al: Utility of preoperative functional magnetic resonance imaging for identifying language cortices in patients with vascular malformations. J Neurosurg 97:2132, 2002 Pouratian N, Bookheimer SY, Rex DE, et al: Utility of preoperative functional magnetic resonance imaging for identifying language cortices in patients with vascular malformations. J Neurosurg 97:21–32, 2002

    • Search Google Scholar
    • Export Citation
  • 106.

    Puce A, , Constable RT, & Luby ML, et al: Functional magnetic resonance imaging of sensory and motor cortex: comparison with electrophysiological localization. J Neurosurg 83:262270, 1995 Puce A, Constable RT, Luby ML, et al: Functional magnetic resonance imaging of sensory and motor cortex: comparison with electrophysiological localization. J Neurosurg 83:262–270, 1995

    • Search Google Scholar
    • Export Citation
  • 107.

    Pujol J, , Conesa G, & Deus J, et al: Clinical application of functional magnetic resonance imaging in presurgical identification of the central sulcus. J Neurosurg 88:863869, 1998 Pujol J, Conesa G, Deus J, et al: Clinical application of functional magnetic resonance imaging in presurgical identification of the central sulcus. J Neurosurg 88:863–869, 1998

    • Search Google Scholar
    • Export Citation
  • 108.

    Rezai AR, , Hund M, & Kronberg E, et al: The interactive use of magnetoencephalography in stereotactic image-guided neurosurgery. Neurosurgery 39:92102, 1996 Rezai AR, Hund M, Kronberg E, et al: The interactive use of magnetoencephalography in stereotactic image-guided neurosurgery. Neurosurgery 39:92–102, 1996

    • Search Google Scholar
    • Export Citation
  • 109.

    Roberts DW, , Hartov A, & Kennedy FE, et al: Intraoperative brain shift and deformation: a quantitative analysis of cortical displacement in 28 cases. Neurosurgery 43:749760, 1998 Roberts DW, Hartov A, Kennedy FE, et al: Intraoperative brain shift and deformation: a quantitative analysis of cortical displacement in 28 cases. Neurosurgery 43:749–760, 1998

    • Search Google Scholar
    • Export Citation
  • 110.

    Roberts TP, , Ferrari P, & Perry D, et al: Presurgical mapping with magnetic source imaging: comparisons with intraoperative findings. Brain Tumor Pathol 17:5764, 2000 Roberts TP, Ferrari P, Perry D, et al: Presurgical mapping with magnetic source imaging: comparisons with intraoperative findings. Brain Tumor Pathol 17:57–64, 2000

    • Search Google Scholar
    • Export Citation
  • 111.

    Romstöck J, , Fahlbusch R, & Ganslandt O, et al: Localisation of the sensorimotor cortex during surgery for brain tumours: feasibility and waveform patterns of somatosensory evoked potentials. J Neurol Neurosurg Psychiatry 72:221229, 2002 Romstöck J, Fahlbusch R, Ganslandt O, et al: Localisation of the sensorimotor cortex during surgery for brain tumours: feasibility and waveform patterns of somatosensory evoked potentials. J Neurol Neurosurg Psychiatry 72:221–229, 2002

    • Search Google Scholar
    • Export Citation
  • 112.

    Roux FE, , Boulanouar K, & Ranjeva JP, et al: Usefulness of motor functional MRI correlated to cortical mapping in Rolandic low-grade astrocytomas. Acta Neurochir 141:7179, 1999 Roux FE, Boulanouar K, Ranjeva JP, et al: Usefulness of motor functional MRI correlated to cortical mapping in Rolandic low-grade astrocytomas. Acta Neurochir 141:71–79, 1999

    • Search Google Scholar
    • Export Citation
  • 113.

    Roux FE, , Ibarrola D, & Tremoulet M, et al: Methodological and technical issues for integrating functional magnetic resonance imaging data in a neuronavigational system. Neurosurgery 49:11451157, 2001 Roux FE, Ibarrola D, Tremoulet M, et al: Methodological and technical issues for integrating functional magnetic resonance imaging data in a neuronavigational system. Neurosurgery 49:1145–1157, 2001

    • Search Google Scholar
    • Export Citation
  • 114.

    Ruge MI, , Victor J, & Hosain S, et al: Concordance between functional magnetic resonance imaging and intraoperative language mapping. Stereotact Funct Neurosurg 72:95102, 1999 Ruge MI, Victor J, Hosain S, et al: Concordance between functional magnetic resonance imaging and intraoperative language mapping. Stereotact Funct Neurosurg 72:95–102, 1999

    • Search Google Scholar
    • Export Citation
  • 115.

    Rutten GJ, , Ramsey NF, & van Rijen PC, et al: Development of a functional magnetic resonance imaging protocol for intraoperative localization of critical temporoparietal language areas. Ann Neurol 51:350360, 2002 Rutten GJ, Ramsey NF, van Rijen PC, et al: Development of a functional magnetic resonance imaging protocol for intraoperative localization of critical temporoparietal language areas. Ann Neurol 51:350–360, 2002

    • Search Google Scholar
    • Export Citation
  • 116.

    Sayawa R, , Hammoud M, & Schoppa D, et al: Neurosurgical outcomes in a modern series of 400 craniotomies for treatment of parenchymal tumors. Neurosurgery 42:10441056, 1998 Sayawa R, Hammoud M, Schoppa D, et al: Neurosurgical outcomes in a modern series of 400 craniotomies for treatment of parenchymal tumors. Neurosurgery 42:1044–1056, 1998

    • Search Google Scholar
    • Export Citation
  • 117.

    Scerrati M, , Roselli R, & Iacoangeli M, et al: Prognostic factors in low grade (WHO grade II) gliomas of the cerebral hemispheres: the role of surgery. J Neurol Neurosurg Psychiatry 61:291296, 1996 Scerrati M, Roselli R, Iacoangeli M, et al: Prognostic factors in low grade (WHO grade II) gliomas of the cerebral hemispheres: the role of surgery. J Neurol Neurosurg Psychiatry 61:291–296, 1996

    • Search Google Scholar
    • Export Citation
  • 118.

    Schaffler L, , Lüders HO, & Beck GJ: Quantitative comparison of language deficits produced by extraoperative electrical stimulation of Broca's, Wernicke's, and basal temporal language areas. Epilepsia 37:463475, 1996 Schaffler L, Lüders HO, Beck GJ: Quantitative comparison of language deficits produced by extraoperative electrical stimulation of Broca's, Wernicke's, and basal temporal language areas. Epilepsia 37:463–475, 1996

    • Search Google Scholar
    • Export Citation
  • 119.

    Schiffbauer H, , Ferrari P, & Rowley HA, et al: Functional activity within brain tumors: a magnetic source imaging study. Neurosurgery 49:13131321, 2001 Schiffbauer H, Ferrari P, Rowley HA, et al: Functional activity within brain tumors: a magnetic source imaging study. Neurosurgery 49:1313–1321, 2001

    • Search Google Scholar
    • Export Citation
  • 120.

    Schlosser M, , Luby M, & Spencer DD, et al: Comparative localization of auditory comprehension by using functional magnetic resonance imaging and cortical stimulation. J Neurosurg 91:626635, 1999 Schlosser M, Luby M, Spencer DD, et al: Comparative localization of auditory comprehension by using functional magnetic resonance imaging and cortical stimulation. J Neurosurg 91:626–635, 1999

    • Search Google Scholar
    • Export Citation
  • 121.

    Schreckenberger M, , Spetzger U, & Sabri O, et al: Localisation of motor areas in brain tumour patients: a comparison of preoperative [18F]FDG-PET and intraoperative cortical electrostimulation. Eur J Nucl Med 28:13941403, 2001 Schreckenberger M, Spetzger U, Sabri O, et al: Localisation of motor areas in brain tumour patients: a comparison of preoperative [18F]FDG-PET and intraoperative cortical electrostimulation. Eur J Nucl Med 28:1394–1403, 2001

    • Search Google Scholar
    • Export Citation
  • 122.

    Schulder M, , Maldjian JA, & Liu WC, et al: Functional image-guided surgery of intracranial tumors located in or near the sensorimotor cortex. J Neurosurg 89:412418, 1998 Schulder M, Maldjian JA, Liu WC, et al: Functional image-guided surgery of intracranial tumors located in or near the sensorimotor cortex. J Neurosurg 89:412–418, 1998

    • Search Google Scholar
    • Export Citation
  • 123.

    Seitz RJ, , Huang Y, & Knorr U, et al: Large-scale plasticity of the human motor cortex. Neuroreport 6:742744, 1995 Seitz RJ, Huang Y, Knorr U, et al: Large-scale plasticity of the human motor cortex. Neuroreport 6:742–744, 1995

    • Search Google Scholar
    • Export Citation
  • 124.

    Signorelli F, , Guyotat J, & Isnard J, et al: The value of cortical stimulations applied to the surgery of malignant gliomas in language areas. Neurol Sci 22:310, 2001 Signorelli F, Guyotat J, Isnard J, et al: The value of cortical stimulations applied to the surgery of malignant gliomas in language areas. Neurol Sci 22:3–10, 2001

    • Search Google Scholar
    • Export Citation
  • 125.

    Simos PG, , Papanicolaou AC, & Berier JI, et al: Localization of language-specific cortex using magnetic source imaging and electrical stimulation mapping. J Neurosurg 91:787796, 1999 Simos PG, Papanicolaou AC, Berier JI, et al: Localization of language-specific cortex using magnetic source imaging and electrical stimulation mapping. J Neurosurg 91:787–796, 1999

    • Search Google Scholar
    • Export Citation
  • 126.

    Skirboll SS, , Ojemann GA, & Berger MS, et al: Functional cortex and subcortical white matter located within gliomas. Neurosurgery 38:678685, 1996 Skirboll SS, Ojemann GA, Berger MS, et al: Functional cortex and subcortical white matter located within gliomas. Neurosurgery 38:678–685, 1996

    • Search Google Scholar
    • Export Citation
  • 127.

    Suess O, , Kombos T, & Hoell T, et al: A new cortical electrode for neuronavigation-guided intraoperative neurophysiological monitoring: technical note. Acta Neurochir 142:329332, 2000 Suess O, Kombos T, Hoell T, et al: A new cortical electrode for neuronavigation-guided intraoperative neurophysiological monitoring: technical note. Acta Neurochir 142:329–332, 2000

    • Search Google Scholar
    • Export Citation
  • 128.

    Szymanski MD, , Perry DW, & Gage NM, et al: Magnetic source imaging of late evoked field responses to vowels: toward an assessment of hemispheric dominance for language. J Neurosurg 94:445453, 2001 Szymanski MD, Perry DW, Gage NM, et al: Magnetic source imaging of late evoked field responses to vowels: toward an assessment of hemispheric dominance for language. J Neurosurg 94:445–453, 2001

    • Search Google Scholar
    • Export Citation
  • 129.

    Tandon P, , Mahapatra AK, & Khosla A: Operations on gliomas involving speech centres. Acta Neurochir Suppl 56:6771, 1993 Tandon P, Mahapatra AK, Khosla A: Operations on gliomas involving speech centres. Acta Neurochir Suppl 56:67–71, 1993

    • Search Google Scholar
    • Export Citation
  • 130.

    Taniguchi M, , Cedzich C, & Schramm J: Modification of cortical stimulation for motor evoked potentials under general anesthesia: technical description. Neurosurgery 32:219226, 1993 Taniguchi M, Cedzich C, Schramm J: Modification of cortical stimulation for motor evoked potentials under general anesthesia: technical description. Neurosurgery 32:219–226, 1993

    • Search Google Scholar
    • Export Citation
  • 131.

    Taylor MD, & Bernstein M: Awake craniotomy with brain mapping as a routine surgical approach to treating patients with supratentorial intraaxial tumors: a prospective trial of 200 cases. J Neurosurg 90:3541, 1999 Taylor MD, Bernstein M: Awake craniotomy with brain mapping as a routine surgical approach to treating patients with supratentorial intraaxial tumors: a prospective trial of 200 cases. J Neurosurg 90:35–41, 1999

    • Search Google Scholar
    • Export Citation
  • 132.

    Vanaclocha V, , Saiz-Sapena N, & Garcia-Casasola C: Surgical treatment of insular gliomas. Acta Neurochir 139:11261135, 1997 Vanaclocha V, Saiz-Sapena N, Garcia-Casasola C: Surgical treatment of insular gliomas. Acta Neurochir 139:1126–1135, 1997

    • Search Google Scholar
    • Export Citation
  • 133.

    Vinas FC, , Zamorano L, & Mueller RA, et al: [15O]-water PET and intraoperative brain mapping: a comparison in the localization of eloquent cortex. Neurol Res 19:601608, 1997 Vinas FC, Zamorano L, Mueller RA, et al: [15O]-water PET and intraoperative brain mapping: a comparison in the localization of eloquent cortex. Neurol Res 19:601–608, 1997

    • Search Google Scholar
    • Export Citation
  • 134.

    Vives KP, & Piepmeier JM: Complications and expected outcome of glioma surgery. J Neurooncol 42:289302, 1999 Vives KP, Piepmeier JM: Complications and expected outcome of glioma surgery. J Neurooncol 42:289–302, 1999

    • Search Google Scholar
    • Export Citation
  • 135.

    Wood CC, , Spencer DD, & Allison T, et al: Localization of human sensorimotor cortex during surgery by cortical surface recording of somatosensory evoked potentials. J Neurosurg 68:99111, 1988 Wood CC, Spencer DD, Allison T, et al: Localization of human sensorimotor cortex during surgery by cortical surface recording of somatosensory evoked potentials. J Neurosurg 68:99–111, 1988

    • Search Google Scholar
    • Export Citation
  • 136.

    Wunderlich G, , Knorr U, & Herzog H, et al: Precentral glioma location determines the displacement of cortical hand representation. Neurosurgery 42:1827, 1998 Wunderlich G, Knorr U, Herzog H, et al: Precentral glioma location determines the displacement of cortical hand representation. Neurosurgery 42:18–27, 1998

    • Search Google Scholar
    • Export Citation
  • 137.

    Yetkin FZ, , Mueller WM, & Morris GL, et al: Functional MR activation correlated with intraoperative cortical mapping. AJNR 18:13111315, 1997 Yetkin FZ, Mueller WM, Morris GL, et al: Functional MR activation correlated with intraoperative cortical mapping. AJNR 18:1311–1315, 1997

    • Search Google Scholar
    • Export Citation
  • 138.

    Yingling CD, , Ojemann S, & Dobson B, et al: Identification of motor pathways during tumor surgery facilitated by multichannel electromyographic recording. J Neurosurg 91:922927, 1999 Yingling CD, Ojemann S, Dobson B, et al: Identification of motor pathways during tumor surgery facilitated by multichannel electromyographic recording. J Neurosurg 91:922–927, 1999

    • Search Google Scholar
    • Export Citation
  • 139.

    Yousry TA, , Schmidt UD, & Jassoy AG, et al: Topography of the cortical motor hand area: prospective study with functional MR imaging and direct motor mapping at surgery. Radiology 195:2329, 1995 Yousry TA, Schmidt UD, Jassoy AG, et al: Topography of the cortical motor hand area: prospective study with functional MR imaging and direct motor mapping at surgery. Radiology 195:23–29, 1995

    • Search Google Scholar
    • Export Citation
  • 140.

    Zentner J, , Hufnagel A, & Pechstein U, et al: Functional results after resective procedures involving the supplementary motor area. J Neurosurg 85:542549, 1996 Zentner J, Hufnagel A, Pechstein U, et al: Functional results after resective procedures involving the supplementary motor area. J Neurosurg 85:542–549, 1996

    • Search Google Scholar
    • Export Citation

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