Hydrocephalus secondary to diffuse villous hyperplasia of the choroid plexus

Case report and review of the literature

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✓ Diffuse villous hyperplasia of the choroid plexus, which is distinct from bilateral choroid plexus papillomas, is extremely rare and is often associated with hydrocephalus due to the overproduction of cerebrospinal fluid (CSF). The authors describe an infant with hydrocephalus, diagnosed by computerized tomography scanning, who developed ascites following placement of a ventriculoperitoneal shunt and, subsequently, demonstrated excessive CSF production when the shunt was externalized. The patient was later successfully treated by placement of a ventriculoatrial shunt. Magnetic resonance imaging demonstrated diffuse villous hyperplasia of the choroid plexus as the cause of the patient's hydrocephalus. The literature on diffuse villous hyperplasia of the choroid plexus is reviewed.

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    Magnetic resonance image with gadolinium enhancement depicting diffuse villous hyperplasia of the choroid plexus. A and B: Hyperplasia of the choroid plexus involving the lateral ventricles (large white arrows). B–D: Hyperplasia of the fourth ventricular choroid plexus protruding through Magendie's foramen (open arrows) and the foramina of Lushke (small white arrows).

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