Granulomatous brain tumor caused by Acanthamoeba

Case report

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✓ A case of a previously healthy 7-year-old girl with a left frontoparietal tumor identified as an Acanthamoeba-induced granuloma is reported, and the literature on Acanthamoeba meningoencephalitis is reviewed. Unlike most reported cases, the Acanthamoeba central nervous system infection presented in this girl as a discrete tumor without meningeal involvement or diffuse encephalitis. A favorable outcome was obtained following total excision of the mass and treatment with ketoconazole.

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Contributor Notes

Address reprint requests to: S. Kwame Ofori-Kwakye, M.D., Department of Neurosurgery, Children's Hospital, 300 Longwood Avenue, Boston, Massachusetts 02115.Address for Dr. Visvesvara: Division of Parasitic Diseases, Centers for Disease Control, Atlanta, Georgia.
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