Unilateral hyperostosis frontalis interna

Case report

Restricted access

✓ The authors describe a case of atypical unilateral prominent hyperostosis frontalis interna in a 50-year-old Japanese woman with psychiatric symptoms. Radiological, computerized tomographic, operative, and histological findings of this rare case are presented.

Article Information

Address reprint requests to: Takeshi Hasegawa, M.D., Department of Neurosurgery, School of Medicine, Kanazawa University, 13–1, Takaramachi, Kanazawa, 920 Japan.

© AANS, except where prohibited by US copyright law.

Headings

Figures

  • View in gallery

    Preoperative plain skull films, left lateral (left) and anteroposterior (right) views, demonstrating left-sided unilateral hyperostosis frontalis interna and absence of the frontal sinus.

  • View in gallery

    Computerized tomography scans before operation. Left: Plain scan showing hyperostotic bone change, which compresses the left frontal lobe. Right: Bone window scan showing bone change characterized by dilatation of the diploic space. There is a high-density area of sclerotic bone attached to the inner table.

  • View in gallery

    Preoperative bone scans, anterior (left) and left lateral (right) views, showing radionuclide uptake over the left squama frontalis.

  • View in gallery

    Postoperative plain computerized tomography scan showing reexpansion of the left frontal lobe.

  • View in gallery

    Photomicrographs of the decalcified specimen. Upper: The expanded diploë consists of spongy trabeculae. The diploë becomes thicker near the inner table. The outer table has been removed. H & E, × 3. Lower: The inner table shows compact lamellar bone with active-looking haversian systems. H & E, × 40.

References

  • 1.

    Canavan MM: Enostoses of the calvarium. Incidence at autopsies in state hospitals. Arch Neurol Psychiatry39:41531938Canavan MM: Enostoses of the calvarium. Incidence at autopsies in state hospitals. Arch Neurol Psychiatry 39: 41–53 1938

  • 2.

    Dann S: Metabolic craniopathy: a review of the literature with report of a case with diabetes insipidus. Ann Intern Med34:1632021951Dann S: Metabolic craniopathy: a review of the literature with report of a case with diabetes insipidus. Ann Intern Med 34:163–202 1951

  • 3.

    Di Chiro GCaughey JE: Skull changes in eighteen cases of dystrophia myotonica. Acta Radiol54:22281960Di Chiro G Caughey JE: Skull changes in eighteen cases of dystrophia myotonica. Acta Radiol 54:22–28 1960

  • 4.

    Eldridge WWHolm GA: The incidence of hyperostosis frontalis interna in female patients admitted to a mental hospital. AJR43:3563591940Eldridge WW Holm GA: The incidence of hyperostosis frontalis interna in female patients admitted to a mental hospital. AJR 43:356–359 1940

  • 5.

    Gegick CGDanowski TSKhurana RCet al: Hyperostosis frontalis interna and hyperphosphatasemia. Ann Intern Med79:71751973Gegick CG Danowski TS Khurana RC et al: Hyperostosis frontalis interna and hyperphosphatasemia. Ann Intern Med 79:71–75 1973

  • 6.

    Gershon-Cohen JSchraer HBlumberg N: Hyperostosis frontalis interna among the aged. AJR73:3963971955Gershon-Cohen J Schraer H Blumberg N: Hyperostosis frontalis interna among the aged. AJR 73:396–397 1955

  • 7.

    Goodman DHEragan A: Gout, myxedema, and hyperostosis frontalis interna. Report of case in Negro woman. JAMA173:173417351960Goodman DH Eragan A: Gout myxedema and hyperostosis frontalis interna. Report of case in Negro woman. JAMA 173:1734–1735 1960

  • 8.

    Grollman ARousseau JP: Metabolic craniopathy. A clinical and roentgenologic study of so-called hyperostosis frontalis interna. JAMA126:2132171944Grollman A Rousseau JP: Metabolic craniopathy. A clinical and roentgenologic study of so-called hyperostosis frontalis interna. JAMA 126:213–217 1944

  • 9.

    Henschen F: Morgagni's Syndrome. Hyperostosis Frontalis Interna Virilismus Obesitas. London/Edinburgh: Oliver and Boyd1949172 ppHenschen F: Morgagni's Syndrome. Hyperostosis Frontalis Interna Virilismus Obesitas. London/Edinburgh: Oliver and Boyd 1949 172 pp

  • 10.

    Jaffe HL: Metabolic Degenerative and Inflammatory Diseases of Bones and Joints. Philadelphia: Lea & Febiger1972 pp 272277Jaffe HL: Metabolic Degenerative and Inflammatory Diseases of Bones and Joints. Philadelphia: Lea & Febiger 1972 pp 272–277

  • 11.

    Knies PTLe Fever HE: Metabolic craniopathy: hyperostosis frontalis interna. Ann Intern Med14:185818921941Knies PT Le Fever HE: Metabolic craniopathy: hyperostosis frontalis interna. Ann Intern Med 14:1858–1892 1941

  • 12.

    Moore MT: The Morgagni-Stewart-Morel syndrome. Report of a case with pneumoencephalographic findings. Arch Intern Med73:7121944Moore MT: The Morgagni-Stewart-Morel syndrome. Report of a case with pneumoencephalographic findings. Arch Intern Med 73:7–12 1944

  • 13.

    Moore S: Hyperostosis frontalis interna. A preliminary study. Surg Gynecol Obstet61:3453621935Moore S: Hyperostosis frontalis interna. A preliminary study. Surg Gynecol Obstet 61:345–362 1935

  • 14.

    Moore S: Metabolic craniopathy. AJR35:30391936Moore S: Metabolic craniopathy. AJR 35:30–39 1936

  • 15.

    Moore S: Acromegaly and contrasting conditions. Notes on roentgenography of the skull. AJR68:565569 1952Moore S: Acromegaly and contrasting conditions. Notes on roentgenography of the skull. AJR 68:565–569 1952

  • 16.

    Murakami N: [Hyperostosis frontalis interna. A review.] Neurol Med15:79871981 (Jpn)Murakami N: [Hyperostosis frontalis interna. A review.] Neurol Med 15:79–87 1981 (Jpn)

  • 17.

    Salmi AVoutilainen AHolsti LRet al: Hyperostosis cranii in a normal population. AJR87:103210401962Salmi A Voutilainen A Holsti LR et al: Hyperostosis cranii in a normal population. AJR 87:1032–1040 1962

  • 18.

    Schüller A: A short review of cranial hyperostoses. Acta Radiol34:3613731950Schüller A: A short review of cranial hyperostoses. Acta Radiol 34:361–373 1950

  • 19.

    Suzuki S: [Practice of Radiography of Head.] Tokyo: Bunkodo1972 pp 146153 (Jpn)Suzuki S: [Practice of Radiography of Head.] Tokyo: Bunkodo 1972 pp 146–153 (Jpn)

  • 20.

    Taveras JMWood EH: Diagnostic Neuroradiologyed 2. Baltimore: Williams and Wilkins1976 Vol 1 pp 1226Taveras JM Wood EH: Diagnostic Neuroradiology ed 2. Baltimore: Williams and Wilkins 1976 Vol 1 pp 1–226

TrendMD

Metrics

Metrics

All Time Past Year Past 30 Days
Abstract Views 196 196 28
Full Text Views 219 219 1
PDF Downloads 167 167 1
EPUB Downloads 0 0 0

PubMed

Google Scholar