Patients vary greatly in their response to pilocarpine and mecholyl, and if studies are to be made, a normal sweating test should be done before sympathectomy and a photograph taken so that accurate comparisons may be made with the results after sympathectomy. Many patients react so weakly to the drugs normally that they are not suitable for study. The lower extremities, unless normally hyperhidrotic, usually respond too weakly to pilocarpine to provide conclusive information.
A heat sweating test should be done within a few days of the corresponding drug test so that the two may be accurately compared. In making our studies concerning cell stations we have conformed to the above principles.