Myopathy associated with epsilon-aminocaproic acid (EACA) therapy

Report of two cases

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  • 1 Department of Neurological Surgery, University of California School of Medicine, San Francisco, and San Francisco Veterans Administration Hospital, San Francisco, California
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✓ The association of myopathy with epsilon-aminocaproic acid (EACA) treatment after subarachnoid hemorrhage in two cases is reported. Clinical and laboratory findings and possible mechanisms are discussed in light of the known pharmacology of the drug. Recovery ensues if EACA treatment is terminated as soon as myopathy appears.

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Contributor Notes

Address for Dr. Weinstein: Section of Neurosurgery, Department of Surgery, College of Medicine, The University of Arizona Health Sciences Center, Tucson, Arizona 85724.Address reprint requests to: Neurosurgery Editorial Office, 350 Parnassus Avenue, Suite 807, University of California, San Francisco, California 94143.
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