Vascular ultrastructure in human meningiomas and schwannomas

Don M. Long M.D., Ph.D.1
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  • 1 Department of Neurosurgery, University of Minnesota Health Sciences Center, Minneapolis, Minnesota
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✓ Nineteen meningiomas and schwannomas have been studied by fluorescence microscopy and electron microscopy. Increased cerebrovascular permeability to protein was demonstrated in each tumor. The anatomical explanation for this increased permeability to protein was found in open endothelial cell junctions, gaps between endothelial cells, and fenestrations in capillary endothelial membranes.

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