Neurological dysfunction in Paget's disease of the vertebral column

Edward S. Sadar M.D.1, Robert J. Walton M.B.1, and Henry H. Gossman M.B., F.R.C.S. (E)1
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  • 1 Department of Medical and Surgical Neurology, Plymouth General Hospital, Plymouth, England
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✓ The authors report four cases of Paget's disease of the vertebral column causing neurological deficit, one with sarcomatous degeneration and one without compression of the spinal cord, and review 86 reported cases. Most cases responded well to decompressive laminectomy. The paradox of neurological deficit without myelographic block is discussed and the relatively common incidence of sarcomatous degeneration noted.

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