1 Laboratory of Pathology, Division of Biologics Standards, and Branch of Surgical Neurology, National Institute of Neurological Diseases and Stroke, and Laboratory of Psychology, National Institute of Mental Health, Department of Health, Education, and Welfare, Bethesda, Maryland
✓ The injection of Pantopaque into the ventricles of normal and hydrocephalic dogs produced a variety of acute and chronic pathological changes. Multiple granulomatous lesions developed in the ventricular wall and the surrounding brain parenchyma, choroid plexus, cranial nerves, and arachnoid membrane. Adhesions formed in several areas of the ventricles, and Pantopaque became encysted in the third ventricle and tips of the temporal horns. In general there were more serious changes in the animals that had a greater degree of hydrocephalus. Relatively mild lesions were noted in normal animals.
BakerHL: Myelographic examination of the posterior fossa with positive contrast medium.Radiology81:791–8011963Baker HL: Myelographic examination of the posterior fossa with positive contrast medium. Radiology 81:
FisherRL: An experimental evaluation of Pantopaque and other recently developed myelographic contrast media.Radiology85:537–5451965Fisher RL: An experimental evaluation of Pantopaque and other recently developed myelographic contrast media. Radiology 85:
JaegerR: Irritating effect of iodized vegetable oils on the brain and spinal cord when divided into small particles.Arch Neurol Psychiat64:715–7191950Jaeger R: Irritating effect of iodized vegetable oils on the brain and spinal cord when divided into small particles. Arch Neurol Psychiat 64:
MilhoratTHClarkRGHammockMKet al: Structural, ultrastructural, and permeability changes in the ependyma and surrounding brain favoring equilibration in progressive hydrocephalus.Arch Neurol22:397–4071970Arch Neurol 22:
ScanlanRL: Positive contrast medium (Iodophendylate) in diagnosis of acoustic neuroma.Arch Otolar (Chicago)80:698–7061964Scanlan RL: Positive contrast medium (Iodophendylate) in diagnosis of acoustic neuroma. Arch Otolar (Chicago) 80:
SteinhausenTBDunganCEFurstJBet al: Iodinated organic compounds as contrast media for radiographic diagnoses. III. Experimental and clinical myelography with ethyl iodophenylundecylate (Pantopaque).Radiology43:230–2341944Radiology 43: