Electrically Induced Thrombosis in Intracranial Aneurysms

S. Mullan 1 , A. J. Raimondi 1 , G. Dobben 1 , G. Vailati 1 and J. Hekmatpanah 1
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1 Division of Neurological Surgery and Department of Radiology, University of Chicago Clinics and Hospitals, Chicago, Illinois
DOI:
https://doi.org/10.3171/jns.1965.22.6.0539
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The occasional observation of spontaneous occlusion of an intracranial aneurysm has suggested the possibility of a surgically induced thrombosis (Fig. 1). Laboratory studies have shown that thrombosis could be produced very easily in artificial aneurysms of the femoral artery of the dog by passage of a small direct electrical current across the sac. Thrombosis in an intact femoral artery required the insertion of an intra-arterial anode and a current of 50 to 2,000 µA. for a period of about 1 to 2 hrs. This clot lasted only a few days and in the course of its

Volume 22: Issue 6 (Jun 1965)

in Journal of Neurosurgery
Cover Journal of Neurosurgery

Article Information

Page Count:
539–547

© AANS, except where prohibited by US copyright law.

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Figures

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    Twenty-three years previously patient had headache and palsy of the 3rd nerve from which he made a subtotal recovery. Left shows calcification adjacent to posterior clinoid. Right shows that this area does not fill with contrast material.

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    Case 10. Progressive thrombosis of aneurysm of genu of anterior cerebral artery over a period of 135 min. Current starting at 200 was gradually increased to 2,000 µA.

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    Case 1. Top right: lateral view. All others are anteroposterior views of aneurysm of internal carotid artery. Bottom right shows subtotal thrombosis after 6½ hrs., 200–2,000 µA.

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    Case 2. Top, anteroposterior and lateral views of aneurysm before thrombosis. Note bilobed appearance on anteroposterior view. Middle, reappearance of aneurysm 2 weeks after complete obliteration. Note persistence of neck only. Bottom, appearance after 7 months.

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    Case 3. Lateral view of aneurysm of internal carotid artery showing progressive thrombosis.

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    Case 3. Top left, anteroposterior view; top right, lateral view pre-operatively. Bottom left, anteroposterior view. Bottom right, lateral view 8 wks. after thrombosis.

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    Case 5. Top, before thrombosis. Middle, immediately after. Bottom, 2 wks. after.

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    Case 8. Anteroposterior views. Left, before; middle, after; right, 4 wks. after thrombosis.

Twenty-three years previously patient had headache and palsy of the 3rd nerve from which he made a subtotal recovery. Left shows calcification adjacent to posterior clinoid. Right shows that this area does not fill with contrast material.

Case 10. Progressive thrombosis of aneurysm of genu of anterior cerebral artery over a period of 135 min. Current starting at 200 was gradually increased to 2,000 µA.

Case 1. Top right: lateral view. All others are anteroposterior views of aneurysm of internal carotid artery. Bottom right shows subtotal thrombosis after 6½ hrs., 200–2,000 µA.

Case 2. Top, anteroposterior and lateral views of aneurysm before thrombosis. Note bilobed appearance on anteroposterior view. Middle, reappearance of aneurysm 2 weeks after complete obliteration. Note persistence of neck only. Bottom, appearance after 7 months.

Case 3. Lateral view of aneurysm of internal carotid artery showing progressive thrombosis.

Case 3. Top left, anteroposterior view; top right, lateral view pre-operatively. Bottom left, anteroposterior view. Bottom right, lateral view 8 wks. after thrombosis.

Case 5. Top, before thrombosis. Middle, immediately after. Bottom, 2 wks. after.

Case 8. Anteroposterior views. Left, before; middle, after; right, 4 wks. after thrombosis.

References

1.

MullanS.BeckmanF. and VailatiG. Simplified thrombosis of a large hypertrophic hemangioma of the scalp. J. Neurosurg.196421: 68–72.Mullan S. Beckman F. and Vailati G. Simplified thrombosis of a large hypertrophic hemangioma of the scalp. J. Neurosurg. 1964 21: 68–72.

2.

MullanS.BeckmanF.VailatiG.KarasickG. and DobbenG. An experimental approach to the problem of cerebral aneurysm. J. Neurosurg.196421: 838–845.Mullan S. Beckman F. Vailati G. Karasick G. and Dobben G. An experimental approach to the problem of cerebral aneurysm. J. Neurosurg. 1964 21: 838–845.

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