Detailed standardized protocol to prevent cerebrospinal fluid shunt infection

Yuma Okamura MD, Keisuke Maruyama MD, PhD, Shin Fukuda MD, Hiroshi Horikawa MD, PhD, Nobuyoshi Sasaki MD, Akio Noguchi MD, PhD, Motoo Nagane MD, PhD and Yoshiaki Shiokawa MD, PhD
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  • Department of Neurosurgery, Kyorin University Faculty of Medicine, Mitaka-City, Tokyo, Japan
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OBJECTIVE

While cerebrospinal fluid (CSF) shunt surgery plays an essential role in the treatment of hydrocephalus, postoperative infection due to the implantation of foreign materials is still one of the most common and potentially serious complications of this procedure. Because no previously reported protocol has been proven to prevent postoperative infection after CSF shunt surgeries in adults, the authors investigated the effectiveness of a protocol introduced in their institution.

METHODS

A detailed standardized surgical protocol to prevent infection in patients undergoing CSF shunt surgeries was introduced in the authors’ institution in December 2011. The protocol included a series of detailed rules regarding the surgical procedure, the surgical environment to minimize contamination from air, double gloving, local injection of antibiotics, and postoperative management. The rate of CSF shunt infection during the 3 years after surgery before and after implementation of the protocol was compared in patients undergoing their first CSF shunt surgeries. The inclusion periods were from January 2006 to November 2011 for the preprotocol group and from December 2011 to December 2014 for the postprotocol group.

RESULTS

The study included 124 preprotocol patients and 52 postprotocol patients. The mean patient age was 59 years in both groups, ranging from 40 days to 88 years. Comparison of patient background factors, including known risk factors for surgical site infections, showed no significant difference between the patient groups before and after implementation of the protocol. While 9 patients (7.3%) developed shunt infections before protocol implementation, no shunt infections (0%) were observed in patients who underwent surgery after protocol implementation. The difference was statistically significant (p = 0.047).

CONCLUSIONS

The authors’ detailed protocol for CSF shunt surgeries was effective in preventing postoperative infection regardless of patient age.

ABBREVIATIONS CSF = cerebrospinal fluid; SSI = surgical site infection.

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Contributor Notes

Correspondence Keisuke Maruyama: Kyorin University, Tokyo, Japan. kskmaru-tky@umin.ac.jp.

INCLUDE WHEN CITING Published online February 15, 2019; DOI: 10.3171/2018.10.JNS181432.

Y.O. and K.M. contributed equally to this work.

Disclosures The authors report no conflict of interest concerning the materials or methods used in this study or the findings specified in this paper.

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