Calcifying pseudoneoplasms of the neuraxis are rare, poorly understood masses that may arise throughout the CNS. Although these lesions are generally considered benign and noninfiltrative, reports exist that document growth of these masses on serial plain radiographs. The authors report a case of a posterior fossa calcifying pseudoneoplasm of the neuraxis demonstrating interval development of peritumoral edema on serial MRI. Their findings suggest that these lesions may sometimes behave in a more aggressive manner than commonly thought.
Abbreviations used in this paper:CAPNON = calcifying pseudoneoplasm of the neuraxis; EMA = epithelial membrane antigen.
Address correspondence to: Kiarash Shahlaie, M.D., Ph.D., Department of Neurological Surgery, University of California Davis School of Medicine, 4860 Y Street, Suite 3740, Sacramento, California 95817. email: email@example.com.
Please include this information when citing this paper: published online February 8, 2013; DOI: 10.3171/2013.1.JNS121755.
FletcherAMGreenleeJJChangKESmokerWRKirbyPAO'BrienEK: Endoscopic resection of calcifying pseudoneoplasm of the neuraxis (CAPNON) of the anterior skull base with sinonasal extension. J Clin Neurosci19:1048–10492012
RodriguezFJScheithauerBWFourneyDRRobinsonCA: Ependymoma and intraparenchymal calcifying pseudoneoplasm of the neural axis: incidental collision or unique reactive phenomenon?. Acta Neuropathol115:363–3662008