Concurrent dural and perimedullary arteriovenous fistulas at the craniocervical junction: case series with special reference to angioarchitecture

Clinical article

Kenichi Sato M.D., Ph.D. 1 , 2 , Toshiki Endo M.D., Ph.D. 2 , Kuniyasu Niizuma M.D., Ph.D. 2 , Miki Fujimura M.D., Ph.D. 3 , Takashi Inoue M.D., Ph.D. 4 , Hiroaki Shimizu M.D., Ph.D. 4 , and Teiji Tominaga M.D., Ph.D. 2
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  • 1 Departments of Neuroendovascular Therapy and
  • 2 Neurosurgery, Tohoku University Graduate School of Medicine;
  • 3 Department of Neurosurgery, National Hospital Organization, Sendai Medical Center; and
  • 4 Department of Neurosurgery, Kohnan Hospital, Sendai, Japan
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Object

Dural arteriovenous fistulas (DAVFs) and perimedullary arteriovenous fistulas (PAVFs) are uncommonly associated in the craniocervical junction. The purpose of this study was to describe the clinical and angiographic characteristics of such concurrent lesions.

Methods

Authors reviewed 9 cases with a coexistent DAVF and PAVF at the craniocervical junction. Clinical presentation, angiographic characteristics, intraoperative findings, and treatment outcomes were assessed.

Results

All patients (male/female ratio 5:4; mean age 66.3 years) presented with subarachnoid hemorrhage. Angiography revealed that 8 patients had both a DAVF and PAVF on the same side, whereas 1 patient had 3 arteriovenous fistulas, 1 DAVF, and 1 PAVF on the right side and 1 DAVF on the left side. All of the fistulas shared dilated perimedullary veins (anterior spinal vein, 7 cases; anterolateral spinal vein, 2 cases) as a main drainage route. The shared drainage route was rostrally directed in 8 of 9 cases. Eight patients exhibited an arterial aneurysm on the distal side of the feeding arteries to the PAVF, and the aneurysm in each case was intraoperatively confirmed as a bleeding point. One patient had ruptured venous ectasia at the perimedullary fistulous point. All patients underwent direct surgery via a posterolateral approach. No recurrence was observed in the 4 patients who underwent postoperative angiography, and no rebleeding event was recorded among any of the 9 patients during the follow-up period (mean 38.4 months).

Conclusions

The similarity of the angioarchitecture and the close anatomical relationship between DAVF and PAVF at the craniocervical junction suggested that these lesions are pathogenetically linked. The pathophysiological mechanism and anatomical features of these lesions represent a unique vascular anomaly that should be recognized angiographically to plan a therapeutic strategy.

Abbreviations used in this paper:AVF = arteriovenous fistula; DAVF = dural AVF; DSA = digital subtraction angiography; ICG = indocyanine green; PAVF = perimedullary AVF; SAH = subarachnoid hemorrhage; VA = vertebral artery.

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Contributor Notes

Address correspondence to: Kenichi Sato, M.D., Ph.D., Department of Neuroendovascular Therapy, Tohoku University Graduate School of Medicine, 2-1 Seiryo-machi, Aoba-ku, Sendai, 980-8575, Japan. email: kenmina@nsg.med.tohoku.ac.jp.

Please include this information when citing this paper: published online November 23, 2012; DOI: 10.3171/2012.10.JNS121028.

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