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Effects of magnetic resonance imaging in patients with implanted deep brain stimulation systems

Clinical article

Valerie Fraix Department of Neurology and Neurosurgery; and
INSERM U836, Grenoble Neuroscience Institute, Joseph Fourier University; and

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 M.D., Ph.D.
,
Stephan Chabardes Department of Neurology and Neurosurgery; and
INSERM U836, Grenoble Neuroscience Institute, Joseph Fourier University; and

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 M.D.
,
Alexandre Krainik Neuroradiology Department, Magnetic Resonance Imaging Unit, University Hospital of Grenoble;
INSERM U836, Grenoble Neuroscience Institute, Joseph Fourier University; and

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 M.D., Ph.D.
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Eric Seigneuret Department of Neurology and Neurosurgery; and
INSERM U836, Grenoble Neuroscience Institute, Joseph Fourier University; and

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 M.D.
,
Sylvie Grand Neuroradiology Department, Magnetic Resonance Imaging Unit, University Hospital of Grenoble;
INSERM U836, Grenoble Neuroscience Institute, Joseph Fourier University; and

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 M.D., Ph.D.
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Jean-François Le Bas Neuroradiology Department, Magnetic Resonance Imaging Unit, University Hospital of Grenoble;
INSERM U836, Grenoble Neuroscience Institute, Joseph Fourier University; and

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 M.D., Ph.D.
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Paul Krack Department of Neurology and Neurosurgery; and
INSERM U836, Grenoble Neuroscience Institute, Joseph Fourier University; and

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 M.D., Ph.D.
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Alim-Louis Benabid Department of Neurology and Neurosurgery; and
INSERM U836, Grenoble Neuroscience Institute, Joseph Fourier University; and
Clinatec, Direction des Recherches Technologiques/Laboratoire d'Electronique et des Technologies de l'Information, Commissariat à l'Energie Atomique, Grenoble, France

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 M.D., Ph.D.
, and
Pierre Pollak Department of Neurology and Neurosurgery; and
INSERM U836, Grenoble Neuroscience Institute, Joseph Fourier University; and

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 M.D.
Page Range:
1242–1245
Volume/Issue:
Volume 113: Issue 6
DOI link:
https://doi.org/10.3171/2010.1.JNS09951
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Object

The aim of this study was to study the effects of MR imaging on the electrical settings of deep brain stimulation (DBS) systems and their clinical consequences.

Methods

The authors studied the effects of 1.5-T MR imaging on the electrical settings of implanted DBS systems, including 1 or more monopolar or quadripolar leads, extension leads, and single- or dual-channel implantable pulse generators (IPGs). The IPG was switched off during the procedure and the voltage was set to 0. The impedances were checked before and after MR imaging.

Results

Five hundred seventy patients were treated with DBS for movement disorders and underwent brain MR imaging after lead implantation and before IPG implantation. None of the patients experienced any adverse events. Thirty-one of these patients underwent 61 additional MR imaging sessions after the entire DBS system had been implanted. The authors report neither local cutaneous nor neurological disorders during or after the MR imaging session. No change in the IPG settings occurred when the magnet reed switch function remained disabled during the procedure.

Conclusions

This study demonstrates that 1.5-T MR imaging can be performed safely with continuous monitoring in patients with a DBS system. The ability to disable the magnet reed switch function of the IPG prevents any change in the electrical settings and thus any side effects. The increasing number of DBS indications and the widespread use of MR imaging indicates the need for defining safety guidelines for the use of MR imaging in patients with implanted neurostimulators.

Abbreviations used in this paper:

DBS = deep brain stimulation; GPi = globus pallidus internus; IPG = implantable pulse generator; RF = radiofrequency; SAR = specific absorption rate; STN = subthalamic nucleus; Vim = ventral intermediate nucleus of the thalamus.
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Volume 113: Issue 6

Contributor Notes

Address correspondence to: Valérie Fraix, M.D., Ph.D., Department of Neurology, University Hospital of Grenoble, BP 217, Grenoble, France 38000. email: valerie.fraix@ujf-grenoble.fr.

Please include this information when citing this paper: published online February 26, 2010; DOI: 10.3171/2010.1.JNS09951.

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