Microsurgical anatomy of the ventral callosal radiations: new destination, correlations with diffusion tensor imaging fiber-tracking, and clinical relevance

Laboratory investigation

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Object

In the current literature, there is a lack of a detailed map of the origin, course, and connections of the ventral callosal radiations of the human brain.

Methods

The authors used an older dissection technique based on a freezing process as well as diffusion tensor imaging to investigate this area of the human brain.

Results

The authors demonstrated interconnections between areas 11, 12, and 25 for the callosal radiations of the trunk and rostrum of the corpus callosum; between areas 9, 10, and 32 for the genu; and between areas 6, 8, and 9 for the ventral third of the body. The authors identified new ventral callosal connections crossing the rostrum between both temporal poles and coursing within the temporal stem, and they named these connections the “callosal radiations of Peltier.” They found that the breadth of the callosal radiations slightly increases along their course from the rostrum to the first third of the body of the corpus callosum.

Conclusions

The fiber dissection and diffusion tensor imaging techniques are complementary not only in their application to the study of the commissural system in the human brain, but also in their practical use for diagnosis and surgical planning. Further investigations, neurocognitive tests, and other contributions will permit elucidation of the functional relevance of the newly identified callosal radiations in patients with disease involving the ventral corpus callosum.

Abbreviations used in this paper: CC = corpus callosum; DT = diffusion tensor.
Article Information

Contributor Notes

Address correspondence to: Johann Peltier, M.D., Department of Neurosurgery, Amiens University Hospital, Victor Pauchet Place, Amiens 80054 cedex 1, France. email: peltier.johann@chu-amiens.fr.Please include this information when citing this paper: published online July 17, 2009; DOI: 10.3171/2009.6.JNS081712.
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References
  • 1

    Aboitiz FScheibel ABFisher RSZaidel E: Fiber composition in the human corpus callosum. Brain Res 598:1431531992

  • 2

    Arguin MLassonde MQuattrini ADel Pesce MFoschi NPapo I: Divided visuo-spatial attention systems with total and anterior callosotomy. Neuropsychologia 38:2832912000

    • Search Google Scholar
    • Export Citation
  • 3

    Bentin SSahar AMoscovitch M: Intermanual information transfer in patients with lesions in the trunk of the corpus callosum. Neuropsychologia 22:6016111984

    • Search Google Scholar
    • Export Citation
  • 4

    Boussaoud DTanné-Gariépy JWannier TRouiller EM: Callosal connections of dorsal versus ventral premotor areas in the macaque monkey: a multiple retrograde tracing study. BMC Neurosci 6:672005

    • Search Google Scholar
    • Export Citation
  • 5

    Brambilla PNicoletti MSassi RBMallinger AGFrank EKeshavan MS: Corpus callosum signal intensity in patients with bipolar and unipolar disorder. J Neurol Neurosurg Psychiatry 75:2212252004

    • Search Google Scholar
    • Export Citation
  • 6

    Carr DBSesack SR: Callosal terminals in the rat prefrontal cortex: synaptic targets and association with GABA-immuno-reactive structures. Synapse 29:1932051998

    • Search Google Scholar
    • Export Citation
  • 7

    Castro-Caldas APoppe PLobo Antunes JCampos J: Partial section of the corpus callosum: focal signs and their recovery. Neurosurgery 25:4424471989

    • Search Google Scholar
    • Export Citation
  • 8

    Clark CRGeffen GM: Corpus callosum surgery and recent memory: a review. Brain 112:1651751989

  • 9

    David AS: Schizophrenia and the corpus callosum: developmental, structural and functional relationships. Behav Brain Res 64:2032111994

    • Search Google Scholar
    • Export Citation
  • 10

    de Lacoste MCKirkpatrick JBRoss ED: Topography of the human corpus callosum. J Neuropathol Exp Neurol 44:5785911985

  • 11

    de Ribet RM: Anatomie schématique de l'appareil nerveux—Systématisation des centres nerveux et de leurs connexions ParisG. Doin & Cie1957

    • Search Google Scholar
    • Export Citation
  • 12

    Debierre C: Le cerveau et la moelle épinière ParisFélix Alcan1907

  • 13

    Dimond SJScammell REBrouwers EYMWeeks R: Functions of the centre section (trunk) of the corpus callosum in man. Brain 100:5435621977

    • Search Google Scholar
    • Export Citation
  • 14

    Duffau HKhalil IGatignol PDenvil DCapelle L: Surgical removal of corpus callosum infiltrated by low-grade glioma: functional outcome and oncological considerations. J Neurosurg 100:4314372004

    • Search Google Scholar
    • Export Citation
  • 15

    Egaas BCourchesne ESaitoh O: Reduced size of corpus callosum in autism. Arch Neurol 52:7948011995

  • 16

    Foong JMaier MClark CABarker GJMiller DHRon MA: Neuropathological abnormalities of the corpus callosum in schizophrenia: a diffusion tensor imaging study. J Neurol Neurosurg Psychiatry 68:2422442000

    • Search Google Scholar
    • Export Citation
  • 17

    Friedman MAMeyers CASawaya R: Neuropsychological effects of third ventricle tumor surgery. Neurosurgery 52:7917982003

  • 18

    Giedd JNBlumental JJeffires NOCastellanos FXLiu HZijdenbos A: Development of the human corpus callosum during childhood and adolescence: a longitudinal MRI study. Prog Neuropsychopharmacol Biol Psychiatry 23:5715881999

    • Search Google Scholar
    • Export Citation
  • 19

    Habib MPelletier J: Neuroanatomie fonctionnelle des relations interhémisphériques. Aspects théoriques et perspectives cliniques. 1. Organisation anatomo-fonctionelle des connexions calleuses. Revue de Neuropsychologie 4:691121994

    • Search Google Scholar
    • Export Citation
  • 20

    Hutter BOSpetzger UBertalanffy JMGilsbach JM: Cognition and quality of life in patients after transcallosal microsurgery for midline tumors. J Neurosurg Sci 41:1231391997

    • Search Google Scholar
    • Export Citation
  • 21

    Jeeves MASimpson DAGeffen G: Functional consequences of the transcallosal removal of intraventricular tumors. J Neurol Neurosurg Psychiatry 42:1341421979

    • Search Google Scholar
    • Export Citation
  • 22

    Kampfl AFranz GAichner FPfausler BHaring HPFelber S: The persistent vegetative state after closed head injury: clinical and magnetic resonance imaging findings in 42 patients. J Neurosurg 88:8098161998

    • Search Google Scholar
    • Export Citation
  • 23

    Kawaguchi Y: Receptor subtypes involved in callosal-induced postsynaptic potentials in rat agranular cortex in vitro. Exp Brain Res 88:33401992

    • Search Google Scholar
    • Export Citation
  • 24

    Keshavan MSDidadkar VAHarenski KRosenberg DRSweeney JAPettegrew JW: Abnormalities of the corpus callosum in first episode, treatment naïve schizophrenia. J Neurol Neurosurg Psychiatry 72:7577602002

    • Search Google Scholar
    • Export Citation
  • 25

    Klingler J: Erleichterung der makroskopischen Praeparation des Gehirns durch den Gefrierprozess. Schweiz Arch Neurol Psychiat 36:2472561935

    • Search Google Scholar
    • Export Citation
  • 26

    Lassonde MSauerwein C: Neuropsychological outcome of corpus callosotomy in children and adolescents. J Neurosurg Sci 41:67731997

  • 27

    Levin HSWilliams DHValastro MEisenberg HMCrofford MJHandel SF: Corpus callosotomy atrophy following closed head injury: detection with magnetic resonance imaging. J Neurosurg 73:77811990

    • Search Google Scholar
    • Export Citation
  • 28

    Mac Master FPKeshavan MSDick ELRosenberg DR: Corpus callosal signal intensity in treatment-naïve pediatric obsessive compulsive disorders. Prog Neuropsychopharmacol Biol Psychiatry 23:6016121999

    • Search Google Scholar
    • Export Citation
  • 29

    Mazza Mdi Rienzo ACostagliola CRoncone RCasacchia MRicci A: The interhemispheric transcallosal-transversal approach to the lesions of the anterior and middle third ventricle: surgical validity and neuropsychological evaluation of the outcome. Brain Cogn 55:5255342004

    • Search Google Scholar
    • Export Citation
  • 30

    Paturet G: Traité d'anatomie humaine Vol 4:ParisMasson et Cie1964

  • 31

    Peterson BSLeckman JFDuncan JSWetzles RRiddle MAHardin MT: Corpus callosum morphology from magnetic resonance images in Tourette's syndrome. Psychiatry Res 55:86991994

    • Search Google Scholar
    • Export Citation
  • 32

    Pujol JVendrell PJunqué CMarti-Vitalta JLCapdevila A: When does human brain development end? Evidence of corpus callosum growth up to adulthood. Ann Neurol 34:71751993

    • Search Google Scholar
    • Export Citation
  • 33

    Raine AHarrison GNReynolds JPSheard CCooper JEMedley I: Structural and functional characteristics of the corpus callosum in schizophrenics, psychiatric controls and normal controls. Arch Gen Psychiatry 47:106010641990

    • Search Google Scholar
    • Export Citation
  • 34

    Rhoton AL: The cerebrum. Neurosurgery 61:1 Suppl371192007

  • 35

    Rumsey JMCasanova MManheim GBPatronas NDe Vaughn NHamburger SD: Corpus callosum morphology, as measured with MRI, in dyslexic men. Biol Psychiatry 39:7697751996

    • Search Google Scholar
    • Export Citation
  • 36

    Sappey Ph C: Traité d'anatomie descriptive vol 3:ParisDelahaye et Lecosnier1877

  • 37

    Suwanwela NCLeelacheavasit N: Isolated corpus callosal infarction secondary to pericallosal artery disease presenting as alien hand syndrome. J Neurol Neurosurg Psychiatry 72:5335362002

    • Search Google Scholar
    • Export Citation
  • 38

    Testut LLatarjet M: Traité d'anatomie humaine Vol 1:ParisG. Doin et Cie1948

  • 39

    Velut SDestrieux CKakou M: Anatomie morphologique du corps calleux. Neurochirurgie 44:17301998

  • 40

    Winkler PAWeis SBuettner ARaabe AAmiridze NReulen HJ: The transcallosal interforniceal approach to the third ventricle: anatomy and microsurgical aspects. Neurosurgery 40:9739821997

    • Search Google Scholar
    • Export Citation
  • 41

    Winkler PAWeis SWenger EHerzog CDahl AReulen HJ: Transcallosal approach to the third ventricle: normative morphometric data based on magnetic resonance imaging scans, with special reference to the fornix and forniceal insertion. Neurosurgery 45:3093191999

    • Search Google Scholar
    • Export Citation
  • 42

    Wong TTKwan SYChang KPHsiu-Mei WYang TFChen YS: Corpus callosotomy in children. Childs Nerv Syst 22:99910112006

  • 43

    Yang YShao YWang JWang PLi X: Small callosal fenestration: anatomical and clinical study. Surg Neurol 70:2522582008

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