Multiple myeloma manifesting as an intraventricular brain tumor

Case report

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Primary intracerebral manifestation of multiple myeloma is rare and usually arises from the meninges or brain parenchyma. The authors present a case of multiple myeloma primarily manifesting within the lateral ventricle. A 67-year-old man was admitted with headache accompanied by slowly progressing right hemiparesis. Magnetic resonance imaging showed a large homogeneous contrast-enhancing intraventricular midline mass and hydrocephalus. The tumor was completely resected, and histopathological examination revealed plasmacytoma. After postoperative radio- and chemotherapy, vertebral osteolysis was detected as a secondary manifestation of multiple myeloma.

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Contributor Notes

Address correspondence to: Astrid Jeibmann, M.D., Institute of Neuropathology, University Hospital Münster Domagkstraße 19, 48149 Münster, Germany. email: astrid.jeibmann@ukmuenster.de.*Drs. Eum and Jeibmann contributed equally to this study.Please include this information when citing this paper: published online November 14, 2008; DOI: 10.3171/2008.2.17652.
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