Responsiveness of short-lasting unilateral neuralgiform headache with conjunctival injection and tearing to hypothalamic deep brain stimulation

Case report

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  • 1 Departments of Neurological Surgery and
  • 2 Neurology, Mayo Clinic Arizona, Pheonix, Arizona
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Short-lasting unilateral neuralgiform headache with conjunctival injection and tearing (SUNCT) is a severe primary headache disorder that is often refractory to medical therapy. Although the pathogenesis of this and other trigeminal autonomic cephalalgias is not completely understood, ipsilateral activation of the posterior and inferior hypothalamus has been identified on functional imaging studies during attacks. The authors report on a case of SUNCT syndrome successfully treated with hypothalamic deep brain stimulation and discuss the current literature.

Abbreviations used in this paper: DBS = deep brain stimulation; SUNCT = short-lasting unilateral neuralgiform headache with conjunctival injection and tearing; TAC = trigeminal autonomic cephalalgia.

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Contributor Notes

Address correspondence to: Mark K. Lyons, M.D., Department of Neurological Surgery, Mayo Clinic Arizona, 5777 East Mayo Boulevard, Phoenix, Arizona 85054. email: lyons.mark2@mayo.edu.
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