Completely endoscopic resection of intraparenchymal brain tumors

Clinical article

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  • Department of Neurological Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania
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Object

The authors introduce a novel technique of intraparenchymal brain tumor resection using a rod lens endoscope and parallel instrumentation via a transparent conduit.

Methods

Over a 4-year period, 21 patients underwent completely endoscopic removal of a subcortical brain lesion by means of a transparent conduit. Image guidance was used to direct the cannulation and resection of all lesions. Postoperative MR imaging or CT was performed to assess for residual tumor in all patients, and all patients were followed up postoperatively to assess for new neurological deficits or other surgical complications.

Results

The histopathological findings were as follows: 12 metastases, 5 glioblastomas, 3 cavernous malformations, and 1 hemangioblastoma. Total radiographically confirmed resection was achieved in 8 cases, near-total in 6 cases, and subtotal in 7 cases. There were no perioperative deaths. Complications included 1 infection and 1 pulmonary embolus. There were no postoperative hematomas, no postoperative seizures, and no worsened neurological deficits in the immediate postoperative period.

Conclusions

Fully endoscopic resection may be a technically feasible method of resection for selected subcortical masses. Further experience with this technique will help to determine its applicability and safety.

Abbreviations used in this paper: CM = cavernous malformation; GBM = glioblastoma multiforme.

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Contributor Notes

Address correspondence to: Johnathan A. Engh, M.D., Department of Neurological Surgery, UPMC Presbyterian, 200 Lothrop Street Suite B-400, Pittsburgh, Pennsylvania 15213. email: enghja@upmc.edu.

Please include this information when citing this paper: published online October 24, 2008; DOI: 10.3171/2008.7.JNS08226.

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