Trigeminal trophic syndrome of all three nerve branches: an underrecognized complication after brain surgery

Case report

Ivica Lukšić M.D., M.Sc.1, Ivana Lukšić M.D.2, Sandra Šestan-Crnek M.D.2, Mihajlo Virag M.D., Ph.D.1, and Darko Macan D.M.D., Ph.D.1
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  • 1 Department of Maxillofacial and Oral Surgery, University Hospital Dubrava, Medical School and School of Dental Medicine, University of Zagreb; and
  • | 2 Department of Clinical Microbiology and Hospital Infection, University Hospital Dubrava, Zagreb, Croatia
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✓The authors report a case of trigeminal trophic syndrome (TTS) that occurred as a complication of a neurosurgical procedure. Three years after a second surgical treatment for a meningioma of the cerebellopontine angle, this 32-year-old woman developed TTS with progressive skin ulcers on the left ala nasi and the left side of the forehead and chin. Trigeminal trophic syndrome is an extremely rare cause of facial ulceration. It occurs as a consequence of trigeminal nerve damage or impaired central sensory connections. To the authors' knowledge, this is the first report of lesions in the dermatomes of all three branches of the nerve after a neurosurgical procedure. Early recognition of this disorder is important, as treatment is difficult and often unsatisfactory. Many clinicians are not aware of this disease, thus, it may be more common than previously thought. The importance of recognizing and diagnosing TTS, as well as its treatment, are discussed.

Abbreviations used in this paper:

TN = trigeminal nerve; TTS = trigeminal trophic syndrome.

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Contributor Notes

Address correspondence to: Ivica Lukšić, M.D., M.Sc., Department of Maxillofacial and Oral Surgery, University Hospital Dubrava, Gojko Susak Avenue 6, 10000 Zagreb, Croatia. email: luksic@kbd.hr.
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