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Phuong D. Nguyen, Ahmed Belal, George N. Washington, Matthew R. Greives, David I. Sandberg, Stephen A. Fletcher, and Manish N. Shah

Transcript 0:26 Patient Presentation . We present a 3-month-old female with a history of right-sided unicoronal craniosynostosis. Here you see vertical dystopia as well as retrusion of the right forehead. As a sequela of her unicoronal craniosynostosis, she also has nasal root deviation to the affected side as well as temporal bulging on the same side. 0:44 CT Imaging . A CT scan is obtained demonstrating the fused right coronal suture and the unicoronal synostosis deformity. A

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Alvin Wong, Arvin R. Wali, Bryan Ryba, Mihir Gupta, Michael L. Levy, and Amanda A. Gosman

Transcript Unicoronal craniosynostosis is one of the most difficult types of craniosynostosis to treat due to its relatively high incidence of relapse, requiring reoperation in over 20% of patients in some case series. Traditional techniques involving removal of the frontal bone and orbital bandeau, ex situ remodeling, and overcorrection have not successfully avoided relapse of the deformity over time. This was our motivation to develop a technique that would preserve vascularity

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Daniela Chieffo, Gianpiero Tamburrini, Luca Massimi, Simona Di Giovanni, Cristina Giansanti, Massimo Caldarelli, and Concezio Di Rocco

findings were compared with normative data. Our aim in the present study was to evaluate the results of a complete cognitive function examination in a series of adolescents who had undergone surgical treatment for SSC when they were younger than 1 year of age. The decision to specifically include only children with isolated sagittal and unicoronal craniosynostosis was based on the fact that more than other even isolated forms of SSC, these defects are considered to be purely cosmetic problems without

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Farshid Farzaneh, Ehsan Moradi, Zohreh Habibi, and Farideh Nejat

white group in Anderson et al.’s study. The total number of bicoronal and unicoronal craniosynostosis cases surpassed other subtypes in this Iranian population. The different pattern of suture involvement in Asian populations can be attributed to either genetic or external influences. A positive family history has been proposed as a significant risk factor, which highlights the role of genetics in craniosynostosis. 2 Cultural aspects may affect the surgical rate as well; the shape of the head in

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Markus J. Bookland, Edward S. Ahn, Petronella Stoltz, and Jonathan E. Martin

craniosynostosis 98.3% 95.0–101.7 85.7% 100% Rt unicoronal craniosynostosis 96.7% 92.0–101.3 83.3% 98.1% Lt unicoronal craniosynostosis 100% NA 100% 100% NA = not applicable. Classification model performance for linear discriminant method. The results were calculated from the iterated model that most closely approximated the mean accuracy of all cross-validated models. Discussion Objective, easily acquired, and reproducible craniometrics

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Todd C. Hankinson, Elizabeth J. Fontana, Richard C. E. Anderson, and Neil A. Feldstein

morphology in nonsyndromic unicoronal craniosynostosis . Anat Rec A Discov Mol Cell Evol Biol 285 : 690 – 698 , 2005 3 Aldridge K , Kane AA , Marsh JL , Yan P , Govier D , Richtsmeier JT : Relationship of brain and skull in pre- and postoperative sagittal synostosis . J Anat 206 : 373 – 385 , 2005 4 Aldridge K , Marsh JL , Govier D , Richtsmeier JT : Central nervous system phenotypes in craniosynostosis . J Anat 201 : 31 – 39 , 2002 5 Amm CA , Denny AD

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Maggie Bellew and Paul Chumas

or learning/language disabilities. In a long-term follow-up of 65 adolescents (approximately 14 years of age) who had undergone surgery for SS or unicoronal craniosynostosis when they were under 12 months of age, Chieffo et al. 7 found that 7% of their sample with SS demonstrated visuospatial and constructional ability defects with associated visual memory recall deficits; 17% also exhibited selective and sustained attention deficits. Approximately one-third (30%) of their sample with anterior

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Christopher L. Kalmar, Zachary D. Zapatero, Mychajlo S. Kosyk, Anna R. Carlson, Scott P. Bartlett, Gregory G. Heuer, Alexander M. Tucker, Jesse A. Taylor, Shih-Shan Lang, and Jordan W. Swanson

craniosynostosis. 1 In infants with premature fusion of either single or multiple sutures, both groups are at risk for elevated ICP. 4 , 9 Incidence of elevated ICP in isolated sagittal craniosynostosis has been reported at 7%–44%, 4 , 13 , 14 and up to 16%–42% in isolated unicoronal craniosynostosis. 12 , 15 Elevated ICP may be mitigated by earlier corrective operative intervention. 5–7 , 13 , 16–19 Patel et al. report worse neurological outcomes in patients who undergo a craniosynostosis procedure after

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Jacques van der Meulen, Joris van der Vlugt, Jolanda Okkerse, and Bert Hofman

closure of the metopic suture. Magnetic resonance imaging observations made by Aldridge et al. 2 have indicated a degree of independence in the dysmorphology of the brain on the one hand and the skull on the other in cases of unicoronal craniosynostosis. Abnormalities in brain development have been shown to be persistent even after corrective surgery for sagittal synostosis. The findings of Shimoji et al. 31 that even children with minimal morphological changes can present with severe

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Stephanie D. C. van de Beeten, Martijn J. Cornelissen, Renee M. van Seeters, Marie-Lise C. van Veelen, Sarah L. Versnel, Sjoukje E. Loudon, and Irene M. J. Mathijssen

revising the article: van de Beeten, Cornelissen, van Veelen, Versnel, Loudon, Mathijssen. Reviewed submitted version of manuscript: all authors. Approved the final version of the manuscript on behalf of all authors: van de Beeten. Statistical analysis: van de Beeten, Cornelissen, van Seeters. Study supervision: Mathijssen. References 1 Alford J , Derderian CA , Smartt JM Jr : Surgical treatment of nonsyndromic unicoronal craniosynostosis . J Craniofac Surg 29 : 1199 – 1207 , 2018