The importance of achieving pain control after spinal surgery has been emphasized by many. Adequate postoperative pain control is associated with improved patient satisfaction, reduced postoperative opioid dependence, shorter hospital length of stay, and lower costs.1 In the current issue of the Journal of Neurosurgery: Spine, Yang et al. use data from the Canadian Spine Outcomes and Research Network (CSORN) to develop a predictive model for identifying patients who had a high or extremely high risk of having inadequate pain control after spinal surgery.2 In their study, 57% of patients experienced inadequate pain control in the first 24 hours after surgery.
The authors used advanced statistical techniques to evaluate 910 patients to develop their model. Using 25 clinical variables, they identified 7 significant ones that were used to develop a simplified 3-tier score to predict risk. In the low-risk tier, patients had a 32% risk of having inadequate pain control (defined as a mean numeric rating scale [NRS] score for pain of > 4 during the first 24 hours after surgery). In the high-risk tier, 63% of patients had inadequate pain control, and for patients in the extremely high–risk category, 85% of patients had inadequate pain control.
The investigators validated their model with 30% of the data (390 patients). Similar results were obtained. Nonmodifiable risk factors included younger age and female sex. Other identified risk factors may or may not be modifiable: preoperative opioid usage (32% of the population), higher Patient Health Questionnaire–9 depression score, fusion surgery, surgery involving 3 or more motion segments, and higher preoperative pain scores.
In many cases, we have choices around which surgical procedure is optimal for specific patients. The threshold for recommending a fusion and for surgically treating 3 or more motion segments differs widely among spinal surgeons. Involving patients and including pain control in the discussion might help educate patients about the benefits and alternatives around the comparative advantages and disadvantages of specific surgical decisions.
The authors suggest that preoperative opioid deprescribing programs and psychotherapy methods, including acceptance and commitment therapy, might help to reduce inadequate postoperative pain control.3,4 Clearly, further study is needed to determine the effectiveness of attempting to modify some risk factors that have a significant behavioral component.
The authors have done a nice job in highlighting the importance of studying postoperative pain control after spinal surgery. There is no question that focusing on patient-centric aspects of care will improve our ability to generate improved outcomes. This study raises many important issues that deserve further study. The assessment of pain control was not standardized in this study. Patients had an average of 9.2 assessments during the first 24 hours. Patients who had NRS scores > 4 but had very satisfactory responses to analgesia might be very different from patients who had suboptimal responses to postoperative analgesia. Determining how best to assess this will require a careful approach. The impact of suboptimal pain control in the first 24 hours and its possible effect on hospital length of stay and on the utilization of postoperative opioids may be more complicated than it might appear. Developing protocols to optimize pain control may not change some of the underlying factors driving longer length of stay and opioid dependence after surgery.
It is essential to have further studies that focus on strategies to improve postoperative pain control in the future. This study by Yang et al. provides some direction by identifying potentially modifiable risk factors. The next step will be to determine how to manage this information and if modification is feasible and effective in optimizing postoperative pain control.
Disclosures
The author reports no conflict of interest.
References
- 1↑
Gerbershagen HJ, Pogatzki-Zahn E, Aduckathil S, Procedure-specific risk factor analysis for the development of severe postoperative pain. Anesthesiology. 2014;120(5):1237–1245.
- 2↑
Yang MMH, Riva-Cambrin J, Cunningham J, Development and validation of a clinical prediction score for poor postoperative pain control following elective spine surgery. J Neurosurg Spine. Published online September 15, 2020. doi:10.3171/2020.5.SPINE20347
- 3↑
Nguyen L-CL, Sing DC, Bozic KJ. Preoperative reduction of opioid use before total joint arthroplasty. J Arthroplasty. 2016;31(9)(suppl):282–287.
- 4↑
Abid Azam M, Weinrib AZ, Montbriand J, Acceptance and Commitment Therapy to manage pain and opioid use after major surgery: preliminary outcomes from the Toronto General Hospital Transitional Pain Service. Can J Pain. 2017;1(1):37–49.
