Cavernous malformations (CMs) are found throughout the CNS but are relatively uncommon in the spine. In this report, the authors describe a giant CM with the imaging appearance of an aggressive, invasive, expansive tumor in the cervical spine. The intradural extramedullary portion of the tumor originated from a cervical nerve root; histologically, the lesion was identified as an intraneural CM. Most of the tumor extended into the paraspinal tissues. The tumor was also epidural, intraosseous, and osteolytic and had completely encased cervical nerve roots, peripheral nerves, branches of the brachial plexus, and the vertebral artery on the right side. It became symptomatic during the puerperal period. Gross-total resection was achieved using staged operative procedures, complex dural reconstruction, spinal fixation, and fusion. Clinical, radiographic, and histological details, as well as a discussion of the relevant literature, are provided.
Abbreviations used in this paper:CM = cavernous malformation; GTR = gross-total resection.
Address correspondence to: Curtis A. Dickman, M.D., c/o Neuroscience Publications, Barrow Neurological Institute, St. Joseph's Hospital and Medical Center, 350 West Thomas Road, Phoenix, Arizona 85013. email: email@example.com.
Please include this information when citing this paper: published online February 24, 2012; DOI: 10.3171/2012.1.SPINE11630.
Safavi-AbbasiSFeiz-ErfanISpetzlerRFKimLDoganSPorterRW: Hemorrhage of cavernous malformations during pregnancy and in the peripartum period: causal or coincidence? Case report and review of the literature. Neurosurg Focus21:1e122006
Sarikaya-SeiwertSGiergaKWessalowskiRSteigerHJHänggiD: Solitary spinal epidural cavernous angiomas in children presenting with acute neurological symptoms caused by hemorrhage. Report of 2 cases. J Neurosurg Pediatr5:89–932010