Editorial. Topical epidural steroids after lumbar spine surgery: do the benefits observed after microdiscectomy extend to lumbar fusion?

Armaan K. Malhotra MD1 and Jefferson R. Wilson MD, PhD, FRCSC1,2
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  • 1 Division of Neurosurgery, St. Michael’s Hospital, University of Toronto, Ontario; and
  • | 2 Institute of Health Policy, Management and Evaluation, University of Toronto, Ontario, Canada
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  • 1

    Deyo RA, Mirza SK, Martin BI, Kreuter W, Goodman DC, Jarvik JG. Trends, major medical complications, and charges associated with surgery for lumbar spinal stenosis in older adults. JAMA. 2010;303(13):12591265.

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    Tavanaei R, Ahmadi P, Malekipour B, et al. Effects of local intraoperative epidural use of triamcinolone acetonide–soaked Gelfoam on postoperative outcomes in patients undergoing posterolateral lumbar spinal fusion surgery: a randomized, placebo-controlled, double-blind trial. J Neurosurg Spine. Published online April 15, 2022. doi:10.3171/2022.1.SPINE211418

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    Aljabi Y, El-Shawarby A, Cawley DT, Aherne T. Effect of epidural methylprednisolone on post-operative pain and length of hospital stay in patients undergoing lumbar microdiscectomy. Surgeon. 2015;13(5):245249.

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    Bahari S, El-Dahab M, Cleary M, Sparkes J. Efficacy of triamcinolone acetonide and bupivacaine for pain after lumbar discectomy. Eur Spine J. 2010;19(7):10991103.

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    Aminmansour B, Khalili HA, Ahmadi J, Nourian M. Effect of high-dose intravenous dexamethasone on post lumbar discectomy pain. Spine (Phila Pa 1976). 2006;31(21):24152417.

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    Arirachakaran A, Siripaiboonkij M, Pairuchvej S, et al. Comparative outcomes of epidural steroids versus placebo after lumbar discectomy in lumbar disc herniation: a systematic review and meta-analysis of randomized controlled trials. Eur J Orthop Surg Traumatol. 2018;28(8):15891599.

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    Ranguis SC, Li D, Webster AC. Perioperative epidural steroids for lumbar spine surgery in degenerative spinal disease. A review. J Neurosurg Spine. 2010;13(6):745757.

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    Mishra LD, Nath SS, Gairola RL, Verma RK, Mohanty S. Buprenorphine-soaked absorbable gelatin sponge: 353 an alternative method for postlaminectomy pain relief. J Neurosurg Anesthesiol. 2004;16(2):115121.

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    Kumari K, Kamal M, Singariya G, et al. Effect of epidural levobupivacaine with or 355 without dexamethasone soaked in gelfoam for postoperative analgesia after lumbar laminectomy: a double 356 blind, randomised, controlled trial. Indian J Anaesth. 2018;62(7):509515.

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  • 1

    Ranguis SC, Li D, Webster AC. Perioperative epidural steroids for lumbar spine surgery in degenerative spinal disease. A review. J Neurosurg Spine. 2010;13(6):745757.

    • Crossref
    • PubMed
    • Search Google Scholar
    • Export Citation
  • 2

    Arirachakaran A, Siripaiboonkij M, Pairuchvej S, et al. Comparative outcomes of epidural steroids versus placebo after lumbar discectomy in lumbar disc herniation: a systematic review and meta-analysis of randomized controlled trials. Eur J Orthop Surg Traumatol. 2018;28(8):15891599.

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    • PubMed
    • Search Google Scholar
    • Export Citation
  • 3

    Haws BE, Khechen B, Patel D V, et al. Impact of local steroid application in a minimally invasive transforaminal lumbar interbody fusion: results of a prospective, randomized, single-blind trial. J Neurosurg Spine. 2018;30(2):222227.

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  • 4

    Jirarattanaphochai K, Jung S, Thienthong S, Krisanaprakornkit W, Sumananont C. Peridural methylprednisolone and wound infiltration with bupivacaine for postoperative pain control after posterior lumbar spine surgery: a randomized double-blinded placebo-controlled trial. Spine (Phila Pa 1976). 2007;32(6):609617.

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