Spinal cord intramedullary arteriovenous malformations (AVMs) have classically been considered congenital lesions that are present from birth. The reason for this dogmatic principal is the fact that a vast majority of these lesions present in pediatric and young adult patients. Interestingly, while many authors have demonstrated the development of de novo nidus-type brain AVMs, there have been no reported cases of a de novo intramedullary or perimedullary AVM of the spine. In this paper the authors describe what they believe to be the first reported case of a de novo AVM of the spinal cord in a young patient who underwent serial imaging from birth for evaluation of a syrinx. Potential pathophysiological mechanisms for the development of de novo vascular malformations of the spinal cord are discussed.
Correspondence Waleed Brinjikji: Mayo Clinic, Rochester, MN. firstname.lastname@example.org.INCLUDE WHEN CITING Published online October 25, 2019; DOI: 10.3171/2019.7.SPINE19253.Disclosures Dr. Patterson reports direct stock ownership in IntraBio; being a consultant for Actelion, Amicus, Novartis, Orphazyme, Shire, and Cerecor; and statistical analysis support from Actelion.
RodeschGHurthMAlvarezHDucotBTadieMLasjauniasP: Angio-architecture of spinal cord arteriovenous shunts at presentation. Clinical correlations in adults and children. The Bicêtre experience on 155 consecutive patients seen between 1981–1999. Acta Neurochir (Wien)146:217–2272004
RodeschG, HurthM, AlvarezH, DucotB, TadieM, LasjauniasP: Angio-architecture of spinal cord arteriovenous shunts at presentation. Clinical correlations in adults and children. The Bicêtre experience on 155 consecutive patients seen between 1981–1999. 146:217–227, 2004)| false