A novel surgical treatment of lumbar disc herniation in patients with long-standing degenerative disc disease by Wenger and Markwalder

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The article by Wenger and Markwalder in this issue of Journal of Neurosurgery: Spine is intriguing and compelling; however, we have several major concerns about this study, including its lack of a control group and the significant unintended bias on the part of the treating physicians and the patients themselves. The desire to achieve a good result, the placebo effect, and intellectual bias can create an aura of undue and inappropriate optimism, as has been demonstrated repeatedly in the medical literature. One merely needs to review the early papers published on the use of threaded interbody

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