Letter to the Editor: Kyphoplasty using bone cement mixed with 153Sm-EDTMP

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To The Editor: It has been proposed that samarium-153-ethylenediaminetetramethylenephosphonic acid (153Sm-EDTMP) mixed with bone cement could prevent local tumor regrowth by irradiation of the rest tumor tissue after kyphoplasty. Analysis of physical and chemical properties of 135Sm-EDTMP and the cement makes it rather implausible. The authors2 describe a method of therapy for metastases in vertebral bodies by kyphoplasty performed using bone cement mixed with 153Sm-EDTMP (Cardoso ER, Ashamalla H, Weng L, et al: Percutaneous tumor curettage and interstitial delivery of samarium-153 coupled with kyphoplasty for treatment

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Please include this information when citing this paper: published online March 15, 2013; DOI: 10.3171/2012.12.SPINE121104.

© AANS, except where prohibited by US copyright law.

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References

1

Ashamalla HCardoso EMacedon MGuirguis AWeng LAli S: Phase I trial of vertebral intracavitary cement and samarium (VICS): novel technique for treatment of painful vertebral metastasis. Int J Radiat Oncol Biol Phys 75:8368422009

2

Cardoso ERAshamalla HWeng LMokhtar BAli SMacedon M: Percutaneous tumor curettage and interstitial delivery of samarium-153 coupled with kyphoplasty for treatment of vertebral metastases. Technical note. J Neurosurg Spine 10:3363422009

3

Lu JDeng JZhao HShi MWang JZhao L: Safety and feasibility of percutaneous vertebroplasty with radioactive (153) Sm PMMA in an animal model. Eur J Radiol 78:2963012011

1

Buchbinder ROsborne RHEbeling PRWark JDMitchell PWriedt C: A randomized trial of vertebroplasty for painful osteoporotic vertebral fractures. N Engl J Med 361:5575682009

2

Cuaron JJHirsch JAMedich DCRosenstein BSMartel CBHirsch AE: A proposed methodology to select radioisotopes for use in radionuclide therapy. AJNR Am J Neuroradiol 30:182418292009

3

Hirsch AERosenstein BSMedich DCMartel CBHirsch JA: Polymethylmethacrylate and radioisotopes in vertebral augmentation: an explanation of underlying principles. Pain Physician 12:8878912009

4

Kallmes DFComstock BAHeagerty PJTurner JAWilson DJDiamond TH: A randomized trial of vertebroplasty for osteoporotic spinal fractures. N Engl J Med 361:5695792009. (Erratum in N Engl J Med 366:970 2012)

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