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To The Editor: It has been proposed that samarium-153-ethylenediaminetetramethylenephosphonic acid (153Sm-EDTMP) mixed with bone cement could prevent local tumor regrowth by irradiation of the rest tumor tissue after kyphoplasty. Analysis of physical and chemical properties of 135Sm-EDTMP and the cement makes it rather implausible. The authors2 describe a method of therapy for metastases in vertebral bodies by kyphoplasty performed using bone cement mixed with 153Sm-EDTMP (Cardoso ER, Ashamalla H, Weng L, et al: Percutaneous tumor curettage and interstitial delivery of samarium-153 coupled with kyphoplasty for treatment
AshamallaHCardosoEMacedonMGuirguisAWengLAliS: Phase I trial of vertebral intracavitary cement and samarium (VICS): novel technique for treatment of painful vertebral metastasis. Int J Radiat Oncol Biol Phys75:836–8422009
CardosoERAshamallaHWengLMokhtarBAliSMacedonM: Percutaneous tumor curettage and interstitial delivery of samarium-153 coupled with kyphoplasty for treatment of vertebral metastases. Technical note. J Neurosurg Spine10:336–3422009