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Richard B. North, Vito R. LaRocca, Jacob Schwartz, Catherine A. North, Marianna Zahurak, Randy F. Davis and Paul C. McAfee

, McBride GG: Surgical management of thoracolumbar spine fractures with incomplete neurologic deficits. Clin Orthop 218: 201–216, 1987 5. Chang EL , Shiu AS , Lii MF , Rhines LD , Mendel E , Mahajan A , et al : Phase I clinical evaluation of near-simultaneous computed tomographic image-guided stereotactic body radiotherapy for spinal metastases. Int J Radiat Oncol Biol Phys 59 : 1288 – 1294 , 2004 Chang EL, Shiu AS, Lii MF, Rhines LD, Mendel E, Mahajan A, et al: Phase I clinical evaluation of near

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Peter C. Gerszten, Anand Germanwala, Steven A. Burton, William C. Welch, Cihat Ozhasoglu and William J. Vogel

LD , Mendel E , Mahajan A , et al : Phase I clinical evaluation of near-simultaneous computed tomographic image-guided stereotactic body radiotherapy for spinal metastases. Int J Radiat Oncol Biol Phys 59 : 1288 – 1294 , 2004 Chang EL, Shiu AS, Lii MF, Rhines LD, Mendel E, Mahajan A, et al: Phase I clinical evaluation of near-simultaneous computed tomographic image-guided stereotactic body radiotherapy for spinal metastases. Int J Radiat Oncol Biol Phys 59: 1288–1294, 2004 10. Chang SD , Adler JR Jr

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Peter C. Gerszten, Steven A. Burton, Cihat Ozhasoglu, William J. Vogel, William C. Welch, Joseph Baar and David F. Friedland

: 253 – 258 , 2004 Cannady SB, Cavanaugh KA, Lee SY, Bukowski RM, Olencki TE, Stevens GH, et al: Results of whole brain radiotherapy and recursive partitioning analysis in patients with brain metastases from renal cell carcinoma: a retrospective study. Int J Radiat Oncol Biol Phys 58: 253–258, 2004 13. Chang EL , Shiu AS , Lii M-F , Rhimes LD , Mendel E , Mahajan A , et al : Phase I clinical evaluation of near-simultaneous computed tomographic image-guided stereotactic body radiotherapy for spinal metastases

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sacral spine with or without aspiration of the cerebrospinal fluid Tao Zhang Zhenhua Li Weiming Gong Bingwei Sun Shuheng Liu Kai Zhang Dezhen Yin Peng Xu Tanghong Jia 8 2007 7 2 145 150 10.3171/SPI-07/08/145 SPI-07_08_145 Phase I/II study of stereotactic body radiotherapy for spinal metastasis and its pattern of failure Eric L. Chang Almon S. Shiu Ehud Mendel Leni A. Mathews Anita Mahajan Pamela K. Allen Jeffrey S. Weinberg Barry W. Brown Xin Shelly Wang Shiao Y. Woo Charles Cleeland Moshe H. Maor Laurence D. Rhines 8 2007 7 2 151 160 10.3171/SPI-07/08/151 SPI

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Eric L. Chang, Almon S. Shiu, Ehud Mendel, Leni A. Mathews, Anita Mahajan, Pamela K. Allen, Jeffrey S. Weinberg, Barry W. Brown, Xin Shelly Wang, Shiao Y. Woo, Charles Cleeland, Moshe H. Maor and Laurence D. Rhines

which his head was stabilized. The beam arrangement, radiation treatment plan, and dose–volume histogram are shown in Fig. 5 . F ig . 5. Stereotactic body radiotherapy for spinal metastasis centered on C-2 with: a nine-coplanar beam arrangement (A), treatment plans shown in axial, sagittal, and coronal views (B), and a dose–volume histogram for spinal metastasis centered on C-2 (C). Cord = spinal cord; GTV = gross tumor volume. The patient underwent an elective tracheostomy to protect his airway passage prior to the simulation. Grade 3 dysphagia and

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Jason P. Sheehan and Jay Jagannathan

JM , Read PW : Evaluation of thoracic spinal cord motion using dynamic MRI . Radiother Oncol 84 : 279 – 282 , 2007 7 Chang EL , Shiu AS , Mendel E , Mathews LA , Mahajan A , Allen PK , : Phase I/II study of stereotactic body radiotherapy for spinal metastasis and its pattern of failure . J Neurosurg Spine 7 : 151 – 160 , 2007 8 De Salles AA , Pedroso AG , Medin P , Agazaryan N , Solberg T , Cabatan-Awang C , : Spinal lesions treated with Novalis shaped beam intensity-modulated radiosurgery and stereotactic

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Peter C. Gerszten and Edward A. Monaco III

B , Ali S , Macedon M , : Percutaneous tumor curettage and interstitial delivery of samarium-153 coupled with kyphoplasty for treatment of vertebral metastases . J Neurosurg Spine 10 : 336 – 342 , 2009 8 Chang EL , Shiu AS , Lii M-F , Rhines LD , Mendel E , Mahajan A , : Phase I clinical evaluation of near-simultaneous computed tomographic image-guided stereotactic body radiotherapy for spinal metastases . Int J Radiat Oncol Biol Phys 59 : 1288 – 1294 , 2004 9 Chang SD , Adler JR Jr : Current status and optimal use of

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Minh Tam Truong, Gregory Grillone, Christine Tschoe, Lawrence Chin, Lisa Ann Kachnic and Scharukh Jalisi

, which uses certain anatomic references (such as the skull, spine, or surgically placed fiducials) as a stereotactic localizer to guide highly focused radiation beams to the tumor in an extracranial site, while maintaining maximal normal tissue sparing to minimize toxicity. Because an invasive stereotactic head frame is no longer required, SBRT can be fractionated, and fractionation potentially allows larger volume targets to be treated compared to SRS. Stereotactic body radiotherapy in HNC can be delivered by LINAC gantry-based systems using relocatable, noninvasive

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Peter C. Gerszten, Edward A. Monaco III, Mubina Quader, Josef Novotny Jr., Jong Oh Kim, John C. Flickinger and M. Saiful Huq

tumors of the spine . J Neurosurg 101 : Suppl 3 413 – 418 , 2004 4 Bilsky MH , Yamada Y , Yenice KM , Lovelock M , Hunt M , Gutin PH , : Intensity-modulated stereotactic radiotherapy of paraspinal tumors: a preliminary report . Neurosurgery 54 : 823 – 831 , 2004 5 Chang EL , Shiu AS , Lii M-F , Rhines LD , Mendel E , Mahajan A , : Phase I clinical evaluation of near-simultaneous computed tomographic image-guided stereotactic body radiotherapy for spinal metastases . Int J Radiat Oncol Biol Phys 59 : 1288 – 1294

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Daniel M. Sciubba, Rory J. Petteys, Mark B. Dekutoski, Charles G. Fisher, Michael G. Fehlings, Stephen L. Ondra, Laurence D. Rhines and Ziya L. Gokaslan

of the adult bony spine . South Med J 89 : 653 – 665 , 1996 26 Cassidy JD , Carroll LJ , Côté P : The Saskatchewan health and back pain survey. The prevalence of low back pain and related disability in Saskatchewan adults . Spine 23 : 1860 – 1867 , 1998 27 Chang EL , Shiu AS , Mendel E , Mathews LA , Mahajan A , Allen PK , : Phase I/II study of stereotactic body radiotherapy for spinal metastasis and its pattern of failure . J Neurosurg Spine 7 : 151 – 160 , 2007 28 Chen TC : Prostate cancer and spinal cord