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Valeri Borger, Motaz Hamed, Julia Taube, Gülsah Aydin, Inja Ilic, Matthias Schneider, Patrick Schuss, Erdem Güresir, Albert Becker, Christoph Helmstaedter, Christian E. Elger, and Hartmut Vatter

freedom was achieved in 65% of patients with TLE. 3 In a recently published review, Englot and Chang reported that the existing data favoring surgery for appropriately selected candidates with refractory TLE are convincing and suggest that a cure is possible in some patients with this disorder. 4 Despite this fact and all achievements of modern presurgical evaluation in recent years, the presurgical prediction of seizure outcome remains difficult. The aim of this study was to evaluate seizure outcome in patients with drug-refractory TLE who underwent rTLS at our

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Patrick Schuss, Julia Marx, Valeri Borger, Simon Brandecker, Ági Güresir, Alexis Hadjiathanasiou, Motaz Hamed, Matthias Schneider, Rainer Surges, Hartmut Vatter, and Erdem Güresir

influence of the surgical strategies (such as resection of the hemosiderin rim) on postoperative seizure outcome in patients with CCM-related epilepsy. 5 , 11 , 12 , 19 A large number of patients with CCM-related epilepsy present with the triggering cavernous lesion located within the temporal lobe, which is considered to be highly epileptogenic. 12 Data on the surgical management and seizure outcome in patients with CCMs located within the temporal lobe only, and CRE, are scarce. Therefore, the purpose of the present study was to assess the institutional data from the

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Gopal K. Dash, Chaturbhuj Rathore, Malcolm K. Jeyaraj, Pandurang Wattamwar, Sankara P. Sarma, and Kurupath Radhakrishnan

cortical dysplasia (FCD) in 19 (27%) patients. 9 Similar to patients with other types of structural lesions, patients with drug-resistant epilepsy and focal gliosis on MRI may benefit from well-planned epilepsy surgery. However, there is a relative dearth of information about the potential problems faced during the presurgical evaluation of patients with focal gliosis, their postsurgical seizure outcome, and the predictors of postoperative outcome. As focal gliosis is a commonly encountered substrate for drug-resistant epilepsy at our center, we planned this study with

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Taner Tanriverdi, Andre Olivier, Nicole Poulin, Frederick Andermann, and François Dubeau

especially in terms of seizure outcome have been found to be comparable to each other. 31 , 50 However, advancing imaging techniques and an evolving body of knowledge related to pathogenetic bases of HS have raised a debate about the relative merit of SelAH versus CorAH for the treatment of MTLE/HS. One key question is whether the epileptogenic zone involves both the lateral temporal cortex and mesial structures or if the latter alone is sufficient to generate seizure in MTLE. It is also still unclear whether more limited surgical approaches produce equal success rates

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Micol Babini, Marco Giulioni, Ercole Galassi, Gianluca Marucci, Matteo Martinoni, Guido Rubboli, Lilia Volpi, Mino Zucchelli, Francesca Nicolini, Anna Federica Marliani, Roberto Michelucci, and Fabio Calbucci

seizure outcome in tumor-related epilepsy lump together a wide variety of tumors (such as pilocytic astrocytomas, oligodendrogliomas, diffuse astrocytomas, gangliogliomas, and DNETs) without distinguishing outcomes between the adult and pediatric populations. Only a few studies are focused on the seizure outcome of LGTs in the pediatric age group alone. 34 , 45 , 51 , 55 , 57 , 69 The purpose of this work is to report our experience with the surgical treatment of focal epilepsy associated with LGTs in children, focusing on the long-term seizure outcome in relation to

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Taner Tanriverdi, André Olivier, Nicole Poulin, Frederick Andermann, and François Dubeau

aim of the present retrospective clinical report is to present the long-term seizure outcome following CC performed at the MNI. We report on a series of 95 patients with a variety of seizure patterns who underwent CC and have now been followed up for 5–25 years (mean 17.2 years). Methods Study Population Between 1981 and 2001, a total of 134 patients underwent CC at the MNI; the records of all patients were retrospectively reviewed. Selection criteria for CC as described previously for this procedure 1 , 3 were as follows: 1) the presence of medically

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Matthias Schneider, Ági Güresir, Valeri Borger, Motaz Hamed, Attila Rácz, Hartmut Vatter, Erdem Güresir, and Patrick Schuss

measurements. In cases of persistent seizures, a subsequent anticonvulsant medication regimen was determined and followed up by the abovementioned specialist disciplines. FIG. 1. Overview of the ILAE classification system as an assessment tool for postoperative seizure outcome. Scheme modified from Wieser et al. 32 Figure is available in color online only. Systematic Review To compare rates of postoperative seizure freedom in our series to previously published data, the present work was expanded with a comprehensive search of peer-reviewed literature. A PubMed search was

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Matthias Schneider, Ági Güresir, Valeri Borger, Motaz Hamed, Attila Rácz, Hartmut Vatter, Erdem Güresir, and Patrick Schuss

measurements. In cases of persistent seizures, a subsequent anticonvulsant medication regimen was determined and followed up by the abovementioned specialist disciplines. FIG. 1. Overview of the ILAE classification system as an assessment tool for postoperative seizure outcome. Scheme modified from Wieser et al. 32 Figure is available in color online only. Systematic Review To compare rates of postoperative seizure freedom in our series to previously published data, the present work was expanded with a comprehensive search of peer-reviewed literature. A PubMed search was

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Marco Giulioni, Guido Rubboli, Gianluca Marucci, Matteo Martinoni, Lilia Volpi, Roberto Michelucci, Anna Federica Marliani, Francesca Bisulli, Paolo Tinuper, Laura Castana, Ivana Sartori, and Fabio Calbucci

migration abnormalities. 2 , 19 , 29 , 42 , 56 The optimal surgical treatment of epileptogenic glioneuronal tumors has not been fully established. Postsurgical seizure outcome of patients with glioneuronal tumors has been evaluated in nonhomogeneous groups, grouping glioneuronal tumors with other tumor types, considering glioneuronal tumors in different brain regions, or grouping together different surgical strategies. 2 , 10 , 11 , 29–31 , 34 , 42 Some investigators consider resection of the tumor alone sufficient for good seizure control, 10 , 11 , 24 , 28 , 30 , 40

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Marco Giulioni, Gianluca Marucci, Matteo Martinoni, Lilia Volpi, Patrizia Riguzzi, Anna Federica Marliani, Francesca Bisulli, Paolo Tinuper, Carlo Alberto Tassinari, Roberto Michelucci, and Guido Rubboli

D rug-resistant MTLE is the most common type of epilepsy requiring surgical treatment, with a favorable seizure outcome being achieved in about 60%–75% of patients. 50 , 51 , 64 , 82 , 89 Clinically, MTLE is often regarded as a relatively homogeneous syndromic entity, with seizures characterized by typical ictal semiology 32 , 96 and EEG findings. 29 , 96 However, a variety of MTLE subtypes have been described according to the underlying etiology, with different surgical prognoses. 47 , 89 , 92 Recent neuropathological classifications of epileptogenic