Search Results

You are looking at 1 - 10 of 8,256 items for :

Clear All
Restricted access

Erkan Kaptanoglu, Selcuk Palaoglu, H. Selcuk Surucu, Mutlu Hayran and Etem Beskonakli

evaluation. In this evaluation, tissues are serially sectioned; every 10th section of tissue is photographed and magnified; and measurements are performed using an image analysis system. Thus, numerical values can be used for statistical analysis. 18 Axonal tracers such as HRP have been used in the quantitative evaluation of SCI. After HRP administration, coronal sections obtained in the cerebrum and midbrain are processed for HRP reactivity. Labeled corticospinal and rubrospinal neurons are counted to determine a cortical score and red nucleus score. The degree of

Restricted access

Fran A. Hardaway, Hanna C. Gustafsson, Katherine Holste, Kim J. Burchiel and Ahmed M. Raslan

patients include, but are not limited to, pain type, 17 , 20 arterial compression, severe neurovascular conflict, 13 , 18 and NVC location (at the root entry zone [REZ]). 10 Currently there is no point-of-care predictive score for the surgical treatment of TN. The existence of such a score would be helpful for counseling patients regarding individual disease-specific prognosis and enhancing a patient-centered approach to care. The objective of this study was to formulate a predictive scoring system that can be used to preoperatively prognosticate the likelihood of

Restricted access

Kelly J. Miller, Karen A. Schwab and Deborah L. Warden

condition into the categories of good recovery (Score 5), moderate disability (Score 4), severe disability (Score 3), vegetative state (Score 2), and dead (Score 1). Since its introduction in 1975 by Jennett and Bond, 9 the GOS has gained widespread use as a research and clinical tool that has enabled comparisons of many different groups of patients with head injury. The scale was intended for broadly describing functional outcome in groups of cases, and some authors have recommended supplementing the GOS with more sensitive and specific scales or even replacing it with

Restricted access

Edward F. Chang, Justin S. Smith, Susan M. Chang, Kathleen R. Lamborn, Michael D. Prados, Nicholas Butowski, Nicholas M. Barbaro, Andrew T. Parsa, Mitchel S. Berger and Michael M. Mcdermott

preoperative prognostication, only patients with non–contrast enhancing lesions were included for analysis. All research activities were approved by the UCSF institutional review board for human research. All preoperative clinical and radiographic features were derived from hospital charts. Clinical variables were recorded, including patient age, sex, presence of seizures and other symptoms on presentation, and KPS score. Preoperative MR images were reviewed while the reviewers remained blinded to patient outcome. Digital caliper measurements of the maximum tumor

Restricted access

Ibrahim Hussain, Ori Barzilai, Anne S. Reiner, Lily McLaughlin, Natalie M. DiStefano, Shahiba Ogilvie, Anne L. Versteeg, Charles G. Fisher, Mark H. Bilsky and Ilya Laufer

T umor-associated spinal instability serves as a major source of morbidity in patients with metastatic cancer and has been defined as “movement-related pain, symptomatic or progressive deformity, and/or neurologic compromise under physiologic loads.” 5 The Spinal Instability Neoplastic Score (SINS) facilitates detection of tumor-associated spinal instability and improves communication among oncology physicians. 5 , 6 Furthermore, SINS serves as a key patient population descriptor in clinical studies trials. 10 , 12 SINS consists of 5 radiographic components

Restricted access

Joseph P. Herbert, Sidish S. Venkataraman, Ali H. Turkmani, Liang Zhu, Marcia L. Kerr, Rajan P. Patel, Irma T. Ugalde, Stephen A. Fletcher, David I. Sandberg, Charles S. Cox Jr., Ryan S. Kitagawa, Arthur L. Day and Manish N. Shah

cohort and determined that the risk factors for pediatric BCVI are similar to those in the adult population. Thus, EAST recommended a screening score for the pediatric trauma population that is very similar to those used for adults. 12 , 35 Subsequently, several studies attempted to validate the use of adult screening criteria in pediatric BCVI, including the Denver group, which found that only 30% of symptomatic children with BCVI met their previously reported adult screening criteria. 32 Recently, however, Ravindra et al. at the University of Utah School of

Restricted access

Vincent C. Traynelis and Hussein Alahmadi

The management of thoracolumbar burst fractures varies considerably among spine surgeons. The load-sharing classification was initially published to predict the success of short-segment posterior fusions for thoracolumbar burst fractures. 5 In the following paper, Radcliff et al. studied the relationship between the load-sharing score (LSS) and different aspects of these burst fractures. 7 They concluded that the LSS did not correlate with posterior ligamentous complex (PLC) injury, neurological status, or management decision. An interesting finding in

Restricted access

Dominik Diesing, Stefan Wolf, Jenny Sommerfeld, Asita Sarrafzadeh, Peter Vajkoczy and Nora F. Dengler

): high Fisher grade, acute hydrocephalus (aHP), intracerebral hemorrhage (ICH), intraventricular hemorrhage (IVH), high Hunt and Hess grade, rehemorrhage, posterior circulation location of the aneurysm, age ≥ 60 years, and female sex. 28 Certain attempts have been made to define scores for predicting the occurrence of SDHC. For example, the failure risk index (FRI) score included the following parameters: third ventricular diameter, Hunt and Hess grade, CSF protein levels, sex, and posterior circulation location of the aneurysm. 4 So far, the FRI score has not gained

Restricted access

Abhaya V. Kulkarni, Ruth Donnelly and Iffat Shams

, consisting of 12 questions. The gold standard for objectively measuring cognitive performance has long been through the use of neuropsychological tests, including traditional IQ testing and other specific tests. We embarked on a study to assess detailed objective neuropsychological performance in a diverse group of children with treated hydrocephalus, and we compared these results to those obtained from the more subjective parent responses to questions from the HOQ. We hypothesized that, although there might be areas for which the HOQ scores mirror neuropsychological test

Restricted access

Edward F. Chang, Aaron Clark, Randy L. Jensen, Mark Bernstein, Abhijit Guha, Giorgio Carrabba, Debabrata Mukhopadhyay, Won Kim, Linda M. Liau, Susan M. Chang, Justin S. Smith, Mitchel S. Berger and Michael W. McDermott

timing of radiation therapy, 1 , 3 , 7 , 15 as significant variability in treatment of LGG exists between institutions. 1 To address these issues, we recently presented an LGG scoring system based on the retrospective analysis of a single institutional study population. 8 The aim of the scoring system was to derive an easy-to-use and reliable method for prognosticating outcomes preoperatively. Others have also shown that preoperative variables play an important role in prognosis. 1 In our earlier study, multivariate Cox proportional hazard modeling demonstrated