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Central Nervous System Resistance

III. The Effect of Adrenal Cortical Substances on the Central Nervous System

R. G. Grenell and E. L. McCawley

prepared by making a skull defect, measuring 1.3 cm. × 2.0 cm., in one hemisphere, located in the midparietal region. The dura was reflected and the brain exposed to air. In some cases a strong lamplight was focused on the head, both to increase drying of the brain and to keep the animal warm over a long period of time. Aqueous adrenal cortical extracts were administered intramuscularly 1 hour before, immediately following, and 3 hours after exposure of the brain. At the time of exposure, 10 cc./kg. of 1 per cent trypan blue were injected into the saphenous vein. This

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Paul M. Lin, Hushang Javid and Edward J. Doyle

was more marked at the origin of the internal carotid artery, though the lumen at this level was not completely occluded. The internal carotid artery above this level appeared to be of normal consistency. Resection of the common carotid artery including the bifurcation and the proximal 1 inch of the internal carotid artery was carried out. A 3-inch autogenous saphenous vein graft was used to bridge the defect between the common carotid artery and the internal carotid artery. The proximal end-to-end anastomosis between the common carotid artery and the vein graft was

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Robert H. Pudenz, Findlay E. Russell, Arthur H. Hurd and C. Hunter Shelden

it was noted at autopsy that blood had not refluxed into the lateral ventricle and that the longitudinal sinus was not thrombosed. In a later communication Payr 16 described further attempts to connect the lateral ventricle to the internal jugular vein. He used a formalin-fixed, paraffin-treated anterior or posterior tibial artery obtained from dogs or calves. A fresh segment of saphenous vein was drawn over the artery in a manner permitting an intima-to-intima junction with the internal jugular vein. The method was used in 8 patients, with 3 excellent results

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Ira J. Jackson and Stanley M. Fromm

the external carotid artery. However, there was no postoperative arteriogram, and the sole evidence of improvement was the relief of the patient's intermittent attacks of hemiplegia and absence of abnormal neurological findings. Lin et al. , 5 in 1956, reported the only successful restoration of circulation through the thrombotic area by means of excision of the bifurcation of the carotid artery and replacement by a saphenous vein graft. Three months later angiograms proved the graft to be patent. Arnstein 1 recently treated 10 patients by thrombo

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Paradoxic Brain Abscess in Congenital Heart Disease

Report of a Case of Complete Recovery

Kazuo Takeuchi, Sadao Ikeda, Akira Kato and Norio Kagitani

hypertrophy. The QRS complex was 0.12 sec. Roentgenogram of the chest showed no marked abnormality. By analysis of tonocardiographic record the systolic murmur was most remarkable at the left sternal margin of the 4th intercostal space. The murmur was of the Diamond type. The findings of the cardiac catheterization are shown in Table 1 . The cardiac catheter was inserted from the right great saphenous vein; it passed through the right ventricle and reached directly to the aorta. Finally the catheter could be inserted into either the common carotid artery or descending

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Edir B. Siqueira, Bill G. Karras, Abram H. Cannon and Paul C. Bucy

insertion of a catheter from peripheral points has been advocated by numerous authors. Sites of origin of the catheter include the femoral artery, 4, 9 saphenous vein, 21 right radial artery, 18 and right brachial artery. 17 Intravenous techniques 23 have been used successfully in some medical centers. Percutaneous puncture of the subclavian artery by various techniques has been advocated. 1, 6 15 Several authors 10, 12, 15 have used the right brachial artery to visualize the vertebral artery. All have used surgical exposure and cannulation. A #12-gauge arterial

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Maitland Baldwin, Robert Farrier, Frances MacDonald and A. K. Ommaya

a Yellow Springs recorder. An intravenous catheter was inserted in the right long saphenous vein and connected to a slow-running infusion of 5 per cent dextrose in water. Fluid volume given by this method, which was used as a vehicle for administration of drugs, never exceeded 50 cc. Eight animals were subjected to left parietotemporal craniotomy under local anesthesia after endotracheal intubation, induction with Fluothane and maintenance on oxygen and Anectine. 7 In these cases, a cortical epileptogenic lesion was made by direct application of a wafer

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John D. Nofzinger, Louis G. Britt, Francis Murphey and James W. Pate

intracranial attack upon the right-sided aneurysm was thought to be too hazardous, even under profound hypothermic technique. Operation . On March 15, 1963 the previously ligated circulation of the left common carotid artery was reestablished by means of a graft of the saphenous vein. An end-to-end anastomosis was effected between the venous graft and the stump of the left common carotid artery above the previous ligation. An end-to-side anastomosis was effected between the venous graft and the left subclavian artery. The right carotid bifurcation was then exposed

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Paul C. Sharkey

longitudinal sinus with a segment of saphenous vein. Even though these patients all died within 4 months, autopsy showed that blood had not refluxed into the ventricle and the sinus was not thrombosed. Haynes, 8 in 1913, reported on connecting the occipital sinus to the cisterna magna in 1 patient and connecting the cisterna magna to an emissary vein. Both attempts were unsuccessful. Cushing 3 referred, in 1926, to an attempted connection of the 3rd ventricle to the longitudinal sinus with a tube passed through the corpus callosum. He observed that blood did not reflux

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Ghahreman Khodadad and William M. Lougheed

or 2 stitches were then placed between every 2 primary stitches. Traction sutures were used in this procedure. They facilitated the technique and provided equal bites with almost an anatomical suture line. 3. Repair of a Partial Arterial Defect . Ovoid arterial defects measuring 5×1 mm. to 8×1.5 mm. were artificially produced with scissors. They were repaired with venous autografts. The patches were taken from the superficial saphenous vein in the following manner: (a) The vein was exposed and the circulation was stopped by 2 clamps. It was cut