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Shakir I. Shakir, Luis Souhami, Kevin Petrecca, Jose João Mansure, Khushdeep Singh, Valerie Panet-Raymond, George Shenouda, Amal A. Al-Odaini, Bassam Abdulkarim, and Marie-Christine Guiot

prognostic factors associated with disease progression have been identified in patients with atypical meningiomas. However, in most studies a limited sample size precluded a meaningful multivariate analysis. Reports of prognostic factors after multivariate modeling include a high mitotic index, 10 , 12 , 23 Simpson surgical grading, 5 sheeting, 12 presence of necrosis, 12 pial and brain invasion, 16 , 23 lack of PORT, 12 and an STR. 12 Notwithstanding the fact that the number of patients studied in our review is relatively small preventing a definitive conclusion, a

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Marcos Dellaretti, Nicolas Reyns, Gustavo Touzet, François Dubois, Sebastião Gusmão, Júlio Leonardo Barbosa Pereira, and Serge Blond

the majority of the pons and are diffuse in nature with poor prognosis. This latter group, termed diffuse intrinsic brainstem glioma, remains one of the most challenging tumor types, with multiple clinical trials failing to improve survival. 7 , 9 , 11 , 12 , 15 The aim of this study was a retrospective analysis to determine whether histological grade, age, and MRI findings are prognostic factors for survival of patients with brainstem gliomas confirmed by histopathological diagnosis. Methods The study involved a retrospective evaluation of medical records

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Daniel M. Sciubba, Rafael De la Garza Ramos, C. Rory Goodwin, Nancy Abu-Bonsrah, Ali Bydon, Timothy F. Witham, Chetan Bettegowda, Ziya L. Gokaslan, and Jean-Paul Wolinsky

, 12 , 13 This type of resection, achieved via en bloc excision of the specimen, 2 , 3 , 22 , 23 has been associated with decreased local recurrence and improved survival in some series, 13 , 14 , 19 although others have found no difference. 13 , 18 The aim of this study was to report a single-institution experience with the surgical management of spinal sarcomas, and to investigate the influence of various prognostic factors and application of the Enneking classification system on local recurrence and survival. Methods Study Population and Data

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George H. Weiss and William F. Caveness

✓ A group of 356 patients who received head injuries in the Korean War during 1951–1953 have been reviewed with special concern for the prognostic indicators in posttraumatic epilepsy. Factors that operate in the occurrence of seizures after craniocerebral trauma are degree of brain destruction, length of coma, and, to a lesser extent, site of injury. None of these factors is related to the persistence of attacks once they have begun. For the latter, the most useful prognostic factors are derived from the time of onset and frequency of seizures.

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Nicola Montano, Quintino Giorgio D'Alessandris, Manuela D'Ercole, Liverana Lauretti, Roberto Pallini, Rina Di Bonaventura, Giuseppe La Rocca, Federico Bianchi, and Eduardo Fernandez

, 36 , 39 , 42 , 44 , 47 , 48 , 54 , 55 , 57 , 58 and Table 3 . 1 , 6 , 8–10 , 12 , 20 , 24 , 29 , 31 , 37 , 38 , 40 , 41 , 46 , 52 , 53 , 56 , 59 TABLE 2. Literature review of surgical series of peripheral nerve tumors with more than 30 cases Authors & Year No. of Pts Histopathology (%) Location (%) Follow-Up (mos) * Prognostic Factors † Stat Anghileri et al., 2006 205 MPNST (100) Head/neck (4), trunk (51), extremities (45) 112 (54–160) Recurrent disease↓, tumor size >5 cm↓, central location↓, GTR↑, RT

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Fritz R. Murray, James W. Snider, Ralf A. Schneider, Marc Walser, Alessandra Bolsi, Alessia Pica, Antony J. Lomax, and Damien C. Weber

and OS, respectively). As a result, univariate and multivariate analyses ( Tables 5 and 6 ) for LC, DFS, and OS, based on key surgical and adjuvant therapy prognostic factors, were performed for the entire cohort with these histologies combined. After stratification for treatment era, analysis of the treated volumes showed a significant increase in size of planning treatment volumes (PTVs) for patients treated after 2007 (increase of the median PTV subclinical dose [PTV1] by 40%, p = 0.01). The median PTV prescription dose (PTV2) increased by 18% but was not

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Pierina Navarria, Federico Pessina, Elena Clerici, Zefferino Rossini, Davide Franceschini, Giuseppe D’Agostino, Ciro Franzese, Tiziana Comito, Mauro Loi, Matteo Simonelli, Elena Lorenzi, Pasquale Persico, Letterio Salvatore Politi, Marco Grimaldi, Lorenzo Bello, Armando Santoro, Maurizio Fornari, Franco Servadei, and Marta Scorsetti

assessing the role of other prognostic factors as well as molecular features. In addition, no conclusive evidence exists about the optimal therapeutic strategies for AGs and the impact of the amount of resection—widely evaluated in low-grade glioma or glioblastoma (GBM). Hence, we reviewed data of newly diagnosed AG patients treated at our institution who were classified according to the new WHO 2016 CNS classification. The primary aim was to identify prognostic factors, other than IDH status, eventually having an impact on outcome. Methods Patients All patients were

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Dominique Figarella-Branger, Muriel Civatte, Corine Bouvier-Labit, Joany Gouvernet, Danielle Gambarelli, Jean-Claude Gentet, Gabriel Lena, Maurice Choux, and J. F. Pellissier

in this age range, following astrocytoma and medulloblastoma. Most ependymomas in children occur in supratentorial or posterior fossa locations, and the prognosis for these patients remains poor, especially for young children. No clear improvement has been observed when using new postoperative treatments including intensive chemotherapy and hyperfractionated radiotherapy. 2 Although some definitive prognostic factors have emerged, such as the extent of tumor resection and the age of the patient, tumor location and histological composition and the role of adjuvant

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Grant W. Mallory, Shanna Fang, Caterina Giannini, Jamie J. Van Gompel, and Ian F. Parney

E : Treatment of metastasising GRF-producing tumour with a long-acting somatostatin analogue . Lancet 324 : 282 – 283 , 1984 45 Wareing TH , Sawyers JL : Carcinoids and the carcinoid syndrome . Am J Surg 145 : 769 – 772 , 1983 46 Williams ED , Sandler M : The classification of carcinoid tumours . Lancet 281 : 238 – 239 , 1963 47 Yao JC , Hassan M , Phan A , Dagohoy C , Leary C , Mares JE , : One hundred years after “carcinoid”: epidemiology of and prognostic factors for neuroendocrine tumors in 35,825 cases in the

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Hans-Jakob Steiger, Bernd Turowski, and Daniel Hänggi

at our institution, most of the patients present for consultation with the diagnosis of SCCM and related symptoms, which are the reasons for MR imaging. Nonetheless, a conclusive answer regarding the frequency of asymptomatic SCCM appears premature in view of the rarity of the entity. There are now a number of reports available of cases or small series of surgically managed SCCM. Most agree that the outcome is not uniformly positive. The purpose of the present update is to analyze our experience in light of prognostic factors. The main focus is on surgically