Search Results

You are looking at 1 - 10 of 1,143 items for :

  • Refine by Access: all x
Clear All
Restricted access

Michael L. J. Apuzzo, Lycurgus M. Davey, and Elias E. Manuelidis

A n apoplectic event may be the first manifestation of a neoplasm of the central nervous system. The syndrome of pituitary apoplexy has been particularly well defined. It has been suggested that the administration of anticoagulant medication in the presence of an underlying neoplasm may increase the risk of hemorrhage associated with that lesion. 16, 29 This report documents the evolution of a pineal region syndrome 4 secondary to a hemorrhage into a pineal cyst in a patient under anticoagulant therapy. Case Report This 56-year-old man had suffered

Restricted access

Umberto DeGirolami and Henry Schmidek

D uring the past 52 years an average of only one case of tumor of the pineal region has been treated at this hospital annually. The 53 such cases collected included 35 histologically verified tumors and 18 histologically unverified tumors. The histologically verified tumors were 14 germinomas, 3 teratomas, 3 pineocytomas, 5 pineoblastomas, and 10 gliomas. The confusing nomenclature applied to the diverse neoplasms occurring in the pineal region has been comprehensively reviewed by Russell and Rubinstein 11 and Rubinstein. 9 Their classification will be

Restricted access

Wolff M. Kirsch and John C. Stears

T umors originating in the pineal gland, irrespective of tissue type, are relatively infrequent. Their incidence in American and European brain tumor series 1, 7 is less than 1%; the frequency in Japanese series 6 has been reported as high as 5%. Tumors of the pineal region have been classified by Russell and Rubinstein 12 into four principal categories: teratomas, pinealomas, glial tumors, and epidermoid or pearly tumors. Tumors qualifying for inclusion in the latter category are distinct rareties. We found only seven unequivocal cases of pineal epidermoid

Open access

David S. Hersh, Scott Boop, and Frederick A. Boop

Transcript In this video, we describe a posterior interhemispheric transcallosal approach for resection of a recurrent pineal region teratoma. 0:27 History and Exam The patient was a 6-year-old male who initially presented to an outside hospital with headaches and was found to have a pineal region mass with obstructive hydrocephalus. He underwent an endoscopic biopsy and VP shunt placement, with subsequent placement of two additional Ommaya catheters into cystic components of the mass. The diagnosis was consistent with a mixed germ cell tumor

Full access

Kaan Yağmurlu, Hasan A. Zaidi, M. Yashar S. Kalani, Albert L. Rhoton Jr., Mark C. Preul, and Robert F. Spetzler

P ineal region tumors are challenging to access due in large part to their central location within the calvaria and critical surrounding neurovascular structures. Harvey Cushing performed pineal region surgery only for palliative measures, noting “personally, I have never succeeded in exposing a pineal region tumor sufficiently well to justify an attempt to remove it.” 16 Numerous tumors can occupy this area, including tumors originating in the pineal body (pinealoblastoma/pineocytomas, teratoma, and germinomas), splenium of the corpus callosum (intrinsic

Restricted access

Yusuf Erşahin

I read with interest the article by Yamini, et al., (Yamini B, Refai D, Rubin CM, et al: Initial endoscopic management of pineal region tumors with associated hydrocephalus: clinical series and literature review. J Neurosurg (Pediatrics 5) 100:4 37–441, May, 2004) regarding the initial management of pineal region tumors. We published the results of endoscopic biopsy for intraventricular tumors in 18 patients between 1991 and 2001 1 after these authors had submitted their paper. Of 18 patients, seven had a tumor in the pineal region and noncommunicating

Restricted access

Kenneth G. Jamieson

T his paper reports the excision of pineal tumors in six patients, without operative death. The cases are drawn from over 1000 cerebral tumors treated at the Royal Brisbane Hospital and the Royal Children's Hospital, Brisbane, since 1956. All patients with localized tumors of the pineal region have been so treated. The first of the six patients was operated on by the technique described by Poppen; 3 difficulty was experienced with exposure, and hemianopia resulted. A modification of this technique was adopted for the remaining five, who suffered no lasting

Restricted access

Pineal and suprasellar germinomas

Results of radiation treatment

R. Derek T. Jenkin, W. John K. Simpson, and Colin W. Keen

U ntil recently, tumors in the pineal region were treated most often by relief of increased intracranial pressure with a shunt and irradiation, without a tissue diagnosis. Classically there has been a high operative mortality rate of 30% to 50% associated with biopsy or resection at this site. 4, 5, 7, 10, 16, 18, 27 A high proportion of these patients responded very well to radiation treatment and 50% to 80% were alive 5 years later. 1, 3, 4, 7, 10, 14, 15, 19, 22, 23, 28, 29 However, surgical procedures in the pineal region are now practical, with an

Restricted access

Malignant pineal region tumors

A clinico-pathological study

Edward A. Neuwelt, Mark Glasberg, Eugene Frenkel, and W. Kemp Clark

K rabbe proposed the term “pinealoma” for all tumors arising from the pineal gland and posterior third ventricle. 16 This has led to much confusion in that a variety of different types of tumors have been called by that designation. A common malignant pineal tumor, the germinoma (atypical teratoma), has been commonly classified as a pinealoma. We prefer to reserve the term “pinealoma” for malignant tumors of the pineal parenchymal cells. Tumors of mature cells are “pineocytomas” and those of immature cells “pineoblastomas.” 33 It is the purpose of this

Restricted access

Takamoto Suzuki, Yukimasa Yasumoto, Kazuo Kumami, Kozo Matsumura, Masumi Kumami, Mamoru Mochizuki, Hiroshi Suzuki, and Hideaki Kojima

M ost melanocytic lesions found in the CNS are metastatic. Primary CNS melanoma is very unusual; its incidence has been reported to be 17 of 28,334 cases of primary intracranial tumors treated in Japan. 1 Primary melanocytic lesions in the pineal region are extremely rare. To date, 10 cases of pineal malignant melanoma have been reported in the literature. 2–6, 10, 12–15 Pathological diagnosis of the reported tumors yielded findings of malignant melanoma. In patients whose cases were reported before 1970 and who received no treatment, survival was 3 months