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William E. Thorell, Michael M. Chow, Richard A. Prayson, Mark A. Shure, Sung W. Jeon, David Huang, Emil Zeynalov, Henry H. Woo, Peter A. Rasmussen, Andrew M. Rollins, and Thomas J. Masaryk

efficacy in humans. Optical coherence tomography is an imaging modality initially described by Huang, et al., 15 in 1991. Analogous to B-mode ultrasonography, OCT uses backscattered light to produce high-resolution tomography of optically accessible biological tissues such as the eye, blood vessels, or gastrointestinal tract. 15 The OCT images have near-biopsy resolution and may be used as a nondestructive alternative to biopsy or as a screening step to reduce biopsy sampling error. The purpose of this study was to determine the ability of OCT to demonstrate an

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Christoph J. Griessenauer, Paul M. Foreman, John P. Deveikis, and Mark R. Harrigan

traumatic aneurysms has not been reported. Intraarterial optical coherence tomography (OCT) is approved in the US for imaging of coronary arteries. Optical coherence tomography is a catheter-based optical imaging technique that provides high-resolution cross-sectional images from tissue based on tissue reflectance of near-infrared or infrared light. Image resolution with OCT reaches 8 μm, which is at least 10 times greater than that of any clinically available diagnostic imaging modality. 11 OCT has been used to image the layers of the internal carotid artery (ICA) in

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Anne E. Carolus, Marcel Lenz, Martin Hofmann, Hubert Welp, Kirsten Schmieder, and Christopher Brenke

smallest structure of a peripheral nerve to be discerned by imaging. The ultrastructure of a peripheral nerve—including its single fibers composed of axons, myelin sheath, and Schwann cells—is still beyond the resolution of MRI and sonography. Optical coherence tomography (OCT) is a noninvasive, nonionizing imaging technique that is able to create real-time, high-resolution volumetric images. Since its invention in 1991, OCT has become a powerful diagnostic tool and has entered clinical use for ophthalmology. Furthermore, it has growing potential in other medical fields

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Christopher R. Pasarikovski, Joel Ramjist, Leodante da Costa, Sandra E. Black, and Victor Yang

resonance vessel-wall (MRVW) imaging, and animal histopathological studies. 4 , 8 , 11 These techniques all have limitations, because MRVW imaging has insufficient spatial resolution to directly visualize endothelial injury, and histopathological examinations are ex vivo and unable to provide real-time patterns of injury. 13 Endovascular optical coherence tomography (OCT) imaging is the highest-resolution intravascular imaging modality currently available. This technology has traditionally been used in interventional cardiology, and more recently it has been applied in

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Hun Ho Park, Min Chul Oh, Eui Hyun Kim, Chan Yun Kim, Sun Ho Kim, Kyu-Sung Lee, and Jong Hee Chang

have had contradictory and conflicting results. 1 , 9 , 19 , 25 , 26 , 29 Longstanding compression of the visual tract often results in axonal degeneration, demyelination, and impaired signal conduction. 18 Irreversible visual dysfunction occurs when retinal ganglion cell (RGC) axons die and the retinal nerve fiber layer (RNFL) becomes thinner through a phenomenon known as retrograde degeneration. 2 , 21 Therefore, visual recovery depends on the amount of injury already inflicted on RGC axons before surgery. Optical coherence tomography (OCT) is a noninvasive in

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Christopher R. Pasarikovski, Julia Keith, Leodante da Costa, Joel Ramjist, Yuta Dobashi, Sandra E. Black, and Victor X. D. Yang

animal histopathologic studies. 4 , 14 , 18 Furthermore, the mechanical thrombectomy device may not be the only source of damage to the endothelium during ETV. Prolonged vessel wall exposure to a luminal thrombus can also cause endothelial damage. 22 Reil et al. showed that ligated arteries exposed to thrombus had increased endothelial damage compared with arteries with interrupted flow in the absence of thrombus. 16 Various components of the thrombus can affect endothelial function and morphology. 7 Endovascular optical coherence tomography (OCT) imaging is the

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Pamela R. Sherwood, Thomas R. Hedges III, Carlos E. Mendoza-Santiesteban, Carl B. Heilman, and Julian K. Wu

eyes, demonstrated topographically as the blue/green areas on the thickness maps. Patients with large pituitary adenomas are typically referred for visual field testing to evaluate the effects of optic chiasmal compression. However, visual perimetry testing is subjective and sometimes difficult to interpret. 2 A new algorithm can segment and quantify the GCC layer of the retina on optical coherence tomography (OCT), which uses light waves to visualize a portion of the retina with an image resolution of 5 μm axially. Imaging is typically done by a technician, does

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Ciro Ramos-Estebanez, Maryo Kohen, Jonathan Pace, Alireza Bozorgi, Sunil Manjila, Vilakshan Alambyan, Ifeyinwa Nwankwo, Michael DeGeorgia, Nicholas C. Bambakidis, and Faruk Orge

$900,000 in lifetime support and unpaid taxes per patient ( ). In addition, it limits rehabilitation, impacts survival, 31 and involves an estimated annual loss of more than $209,000 in quality-adjusted life years. 9 , 26 , 27 The potential risk for legal blindness warrants an immediate ophthalmological evaluation in patients with aSAH, and operative removal of intraocular blood if required. 10 , 13 , 14 , 18 , 20 While optical coherence tomography (OCT) is the standard for diagnosis of retinal disease, 6 , 24 its use

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Anne E. Carolus, Jens Möller, Martin R. Hofmann, Johannes A. P. van de Nes, Hubert Welp, Kirsten Schmieder, and Christopher Brenke

the fascicular area by 10%–43% in human cadaver nerves. 12 Optical coherence tomography (OCT) is a new imaging technique that combines high resolution with the possibility of use in vivo. 1 , 3 In a recent feasibility study, we evaluated the technical aspects of OCT to visualize human peripheral nerves during the operation as well as postoperatively. 4 In the present study, we compare OCT images and histological sections of the same peripheral nerves in order to investigate whether the images obtained from the light-backscattering technique correlate with the

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Christopher R. Pasarikovski, Jerry C. Ku, Julia Keith, Joel Ramjist, Yuta Dobashi, Stefano M. Priola, Leodante da Costa, Ashish Kumar, and Victor X. D. Yang

, techniques and their application in endovascular procedures for stroke, aneurysms and vascular malformations . J Cereb Blood Flow Metab . 2019 ; 39 ( 3 ): 375 – 394 . 15 Pasarikovski CR , Ramjist J , da Costa L , Optical coherence tomography imaging after endovascular thrombectomy for basilar artery occlusion: report of 3 cases . J Neurosurg . 2020 ; 133 ( 4 ): 1141 – 1146 . 16 Pasarikovski CR , Keith J , da Costa L , Optical coherence tomography imaging after endovascular thrombectomy: a novel method for evaluating vascular injury in a swine