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Henrik Giese, Benjamin Haenig, Anna Haenig, Andreas Unterberg and Klaus Zweckberger

-onset craniopharyngiomas, severe memory deficits, and attention- and processing-speed impairments, especially in those with hypothalamic involvement. 17 A systematic review by Özyurt et al. confirms that episodic memory recall is particularly impaired. 38 Data for the adult craniopharyngioma cohort, however, is lacking. Bawden et al. only showed a lower performance IQ for patients with craniopharyngioma and concluded that neuropsychological outcome is more benign than expected. 2 Furthermore, in the available studies there were no consistent parameters measuring or comparing

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Andrew S. Little, Kris A. Smith, Kristin Kirlin, Leslie C. Baxter, Steve Chung, Rama Maganti and David M. Treiman

advantages. This corridor preserves functional temporal lobe tissue in the superior, middle, and inferior temporal gyri. It does not disrupt frontotemporal white matter pathways that reside within the temporal stem. Furthermore, the visual fibers near the roof of the temporal horn are spared. In this report, we describe technical modifications to the subtemporal exposure using a minimal-access keyhole approach. Preliminary seizure and neuropsychological outcomes are also presented. Methods Between October 2003 and April 2007, the records of 41 patients with medically

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Viola L. Vogt, Juri-Alexander Witt, Michael P. Malter, Jan-Christoph Schoene-Bake, Marec von Lehe, Christian E. Elger and Christoph Helmstaedter

consequences of these deficits regarding everyday functioning and quality of life have yet to be determined. To address this question, the present investigation evaluated the neuropsychological outcome of a group of patients with bilateral AHS who underwent epilepsy surgery and compared them with a group of patients with the same diagnosis who were not suited for surgery and were treated pharmacologically. The selection of surgical candidates and their seizure outcomes as compared with 291 patients with unilateral AHS are described in detail in a previous paper. 39

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Neurosurgical Forum: Letters to the Editor To The Editor Lawrence F. Marshall , M.D. Howard Tung , M.D. University of California San Diego, California 527 528 In the present issue of the Journal of Neurosurgery , Obwegeser, et al. (Obwegeser AA, Uitti RJ, Lucas JA, et al: Predictors of neuropsychological outcome following microelectrode-guided pallidotomy for Parkinson's disease. J Neurosurg 93: 410–420, September, 2000) describe the neuropsychological changes following microelectrode-guided pallidotomy for Parkinson's disease (PD) in a series of 44

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Barbara P. Uzzell, Walter D. Obrist, Carol A. Dolinskas and Thomas W. Langfitt

± standard error; GCS = Glasgow Coma Scale; GOS = Glasgow Outcome Scale; CT = computerized tomography. † Significance: p < 0.05, chi-square test. Assessment Procedure All subjects were admitted to the Hospital of the University of Pennsylvania, and received an admission CT scan of the brain that was repeated when clinically indicated. The findings of each CT scan were coded and computerized on the basis of a modified classification system for pathology. 42 The neuroradiologist (C.A.D.) had no knowledge of ICP, CBF, or neuropsychological outcome

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Sumeet Vadera, Varun R. Kshettry, Patricia Klaas and William Bingaman

are scant data on the cognitive effect of temporal lobe resection in children. If the severity of neuropsychological deficits is related to duration and severity of seizure disorder, then perhaps earlier surgical intervention may lead to improved overall neuropsychological outcomes in children. 5 , 6 , 11 In this study, we retrospectively reviewed cases of temporal lobectomy for pediatric HS at the Cleveland Clinic, and we report our data regarding seizure freedom and neuropsychological outcomes. Methods We conducted a retrospective review of medical records

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Lyla E. Hampton, Jack M. Fletcher, Paul T. Cirino, Susan Blaser, Larry A. Kramer, James Drake and Maureen Dennis

N eural and cognitive development in children with SB may be compromised not only by the disorder itself, but also by hydrocephalus, 1 , 11–13 , 24 which contributes to variability of neuropsychological outcomes. 11 , 18 , 29 It is important to understand how hydrocephalus affects outcome in SB, if only because some current approaches to treatment delay shunt implantation in many children. 2 Since the 1950s, the most common form of treatment for conditions producing hydrocephalus, including SB, has been implantation of a ventricular shunt to divert

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Alois A. Obwegeser, Ryan J. Uitti, John A. Lucas, Robert J. Witte, Margaret F. Turk and Robert E. Wharen Jr.

S tereotactic ventroposterolateral pallidotomy is an effective treatment for alleviating intractable symptoms in selected patients with advanced PD. 12, 47 There is a surprising diversity in neuropsychological outcomes reported after pallidotomy and no consensus concerning what, if any, cognitive changes occur. Neuropsychological changes after pallidotomy have been reported by our group 26, 46 and by other investigators, 7, 18, 28, 33, 34, 38, 42, 51 whereas some authors have reported no significant neuropsychological changes after pallidotomy. 2, 30, 31, 39

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Tomokatsu Hori, Fumitaka Yamane, Taku Ochiai, Shinji Kondo, Satoru Shimizu, Kenji Ishii and Hajime Miyata

N early 25 years ago, Wieser, Yas¸argil, and their colleagues 36–39 , 42 , 43 suggested that the classic anterior two-thirds temporal lobe resection was too crude for patients in whom presurgical neurophysiological evaluation could define a narrow area of seizure origin within the mediobasal limbic structures. Consequently they developed the technique of selective amygdalohippocampectomy, 43 which is currently a standard procedure for patients with temporal lobe epilespy and has well-established operative and neuropsychological outcomes. If selective

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Peng-Fan Yang, Hui-Jian Zhang, Jia-Sheng Pei, Qiao Lin, Zhen Mei, Zi-Qian Chen, Yan-Zeng Jia, Zhong-Hui Zhong and Zhi-Yong Zheng

short and direct precise route to the mesial temporal structures. The aims of this study were to describe our refined approach and evaluate the seizure and neuropsychological outcomes. Methods This study was a retrospective review of cases involving patients treated for epilepsy due to unilateral hippocampal sclerosis between September 2010 and September 2012 at our institution by means of a selective amygdalohippocampectomy (SAH) via the posterior subtemporal approach through a relatively small craniotomy, without a neuronavigation system. Patients who had