Search Results

You are looking at 1 - 10 of 49 items for :

  • "neonatal meningitis" x
  • All content x
Clear All
Restricted access

Paul Schultz and Norman E. Leeds

H ydrocephalus frequently develops in infants who survive neonatal meningitis and ventriculitis. 7 This may be a communicating hydrocephalus as a result of impaired absorption of cerebrospinal fluid (CSF) from the subarachnoid space, or a noncommunicating hydrocephalus due to obstruction of the foramina of Munro, the aqueduct of Sylvius, or the outlets of the fourth ventricle. 2, 3, 9, 14 We have performed air ventriculography in seven infants who had survived meningitis and then developed hydrocephalus. These studies were done prior to shunting procedures

Restricted access

John E. Kalsbeck, Alonso L. DeSousa, Martin B. Kleiman, Julius M. Goodman, and Edmund A. Franken

compartments in both lateral ventricles and bilateral catheters placed through the membranes extending to the frontal horns. Discussion In the infant who exhibits an enlarging head following neonatal meningitis, the possibility of postinflammatory occlusion of the interventricular foramina, aqueduct, fourth ventricular exits, or the subarachnoid space is usually considered. Septation of the lateral ventricles was not seen in a review of the findings at autopsy of 29 infants with neonatal meningitis. 2 Salmon 8 reported isolated unilateral hydrocephalus

Restricted access

Todd Y. Nida and Stephen J. Haines

V entricular septations causing multiloculated hydrocephalus have been described in association with birth trauma, intraventricular hemorrhage, and tumors, but neonatal meningitis with presumed ventriculitis is the most frequently cited etiology. Other designations include multilocular hydrocephalus, 12 compartmentalized hydrocephalus, 6, 8 ventricular compartmentalization, 7 intraventricular septations, 14 and polycystic brain disease. 3 With the advent of computerized tomography (CT) and magnetic resonance (MR) imaging, the diagnosis has become easier

Restricted access

Benjamin C. Warf

moderately increased protein or moderate lymphocytosis. 18 Malaria is often the presumed diagnosis in febrile infants and in children from places such as Uganda where malaria is endemic and is often treated empirically, thereby possibly delaying the diagnosis and management of other febrile illnesses such as meningitis. 23 A more probable cause of PIHC is meningitis. Neonatal meningitis has been previously associated with ventriculitis, aqueductal obstruction, ventricular loculations, and cerebral infarction. 5, 19, 21 Such conditions were commonly seen in our patients

Restricted access

Brain abscesses in neonates

A study of 30 cases

Dominique Renier, Cécile Flandin, Elizabeth Hirsch, and Jean-François Hirsch

The reported incidence of neurological sequelae varies, with up to 66% of the survivors affected. 3, 6, 29 Some publications dealing with the pathology of neonatal meningitis have emphasized the high incidence of severe widespread damage to cerebral tissue. 4, 8, 13, 33 However, instances of brain abscesses in the newborn infant have been published only as case reports or very short series. 7, 9, 10, 15, 18, 21, 26, 27, 30, 32, 35 The purpose of this paper is to describe the clinical, radiological, bacteriological, and therapeutic features of brain abscesses in

Restricted access

Nasser M. F. El-Ghandour

the 24 patients, neonatal meningitis was the most common cause of the multiloculated hydrocephalus (in 9 patients) followed by IVH (in 6 patients), postoperative gliosis due to previous shunt infection (in 6 patients), and multiple neuroepithelial cysts (in 3 patients). All patients presented with head enlargement, 18 with developmental delay, 4 with epilepsy, and 2 with hemiparesis. Multiplanar Gd-enhanced MR imaging was diagnostic in all patients. All patients had supratentorial multiloculated hydrocephalus, and none had an isolated fourth ventricle. None of the

Restricted access

Jane C. S. Perrin, Martin H. Weiss, and David Yashon

✓ A family with craniofacial dysostosis affecting a father and his monozygotic twin sons is described. The father had no surgery until linear craniectomy when 3 years old; he is of normal intelligence but legally blind. Prophylactic coronal craniectomy and orbital decompression were done on the twins. One had an uncomplicated course and is developing normally. The other developed neonatal meningitis and ventriculitis with secondary hydrocephalus, plus poor vision and retarded development.

Restricted access

Burton L. Wise, Jacob L. Mathis, and Ernest Jawetz

reactions, and therefore may persist for long periods before being diagnosed and properly treated. The characteristics noted above are particularly pertinent to pseudomonas infections of the central nervous system. Pseudomonas is the cause of about 5% of neonatal meningitis. 13, 14 In most instances pseudomonas meningitis has been superimposed on underlying disease, wound infection or cerebrospinal-fluid fistula; has extended from adjacent foci; or has been introduced by lumbar puncture, spinal anesthesia, or indwelling catheters draining cerebrospinal fluid. 2, 3, 5

Restricted access

Andrew G. Parrent

L oculated hydrocephalus most frequently arises as a sequela of neonatal meningitis or intraventricular hemorrhage. 2, 6, 10 It may also complicate severe shunt placement—associated infections and some forms of adult meningitis. 4, 10, 11 A number of methods have been used to address this problem, including endoscopic surgery, 3, 6, 12 which has been demonstrated to be a safe, minimally invasive procedure in which loculations are opened to allow them to communicate freely with the ventricular system, thereby avoiding implantation of multiple shunts and, in

Restricted access

Giorgio Mombelli, Jean Klastersky, Lyne Coppens, Didier Daneau, and Yves Nubourgh

unsatisfactory. In a recent series, which included various forms (neonatal, spontaneous, postsurgical) of meningitis, mortality rates varied from 43% to 91% depending on the causative organism. 6 In that study, for P. aeruginosa and Klebsiella sp. (the most frequent pathogens in our series), the mortality rate was 83% and 91%, respectively. Fatality rates have recently been reported as 40% and 50% for spontaneous GNBM in adults, 6, 7 and are also in excess of 30% for neonatal meningitis. 17, 18 In the present series, the extremely high overall mortality rate resulted