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1 40 44 10.3171/jns.1944.1.1.0040 Multiple Meningiomas. Report of Two Cases Joseph A. Mufson Leo M. Davidoff January 1944 1 1 45 57 10.3171/jns.1944.1.1.0045 A Perforator and Ball Burr Kenneth G. McKenzie January 1944 1 1 58 59 10.3171/jns.1944.1.1.0058 Cerebrospinal Rhinorrhea—Surgical Repair William J. German January 1944 1 1 60 66 10.3171/jns.1944.1.1.0060 The Lucite Calvarium—A Method for Direct Observation of the Brain Lieut. C. Hunter Shelden Lieut. Robert H. Pudenz Lt. Comdr. Joseph S

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Joseph A. Mufson and Leo M. Davidoff

I n cushing's series 3 of 2,203 verified intracranial tumors, the meningiomas comprised 13.4 per cent. The incidence has been reported as somewhat higher by others (Olivecrona, 13 15.8 per cent; Craig, 16 14.9 per cent; Horrax, 10 19 per cent). Despite its frequent occurrence among brain tumors, the meningioma is rarely seen as a multiple growth unless one includes those cases of centralized neurofibromatosis, a manifestation of von Recklinghausen's disease, in which the dura is often studded with innumerable small meningiomas. Cushing and Eisenhardt 3

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Gilbert Horrax

of the patients—all these and many other minutiae assembled by himself and his co-workers were brought to bear. In the Cavendish Lecture for 1922, 23 he coined the term “meningioma” for the group of tumors heretofore listed by a variety of names, but usually that of dural endothelioma. Using his extensive material he was able to pick out from the whole mass of these tumors different groups which always grew in specific locations, often giving specific symptoms, so that, before operation, they could be recognized and operative plans laid accordingly. This

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J. Grafton Love

: neurologic findings . Finding Cases Totals Paraplegia, sensory level discernible 1 * Ankle jerk diminished or absent 10 17 Knee jerk diminished or absent 5 Foot drop (bilateral) 1 Neurologically negative 9 9  Totals 26 26 * Meningioma T-10; multiple disks. It is known that in the presence of ependymomas of the filum terminale, the concentration of total protein in the cerebrospinal fluid tends to be high and, with this knowledge, on several occasions I have been

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Edgar F. Fincher, Bronson S. Ray, Harold J. Stewart, Edgar F. Fincher, T. C. Erickson, L. W. Paul, Franc D. Ingraham, Orville T. Bailey, Frank E. Nulsen, James W. Watts, Walter Freeman, C. G. de Gutiérrez-Mahoney, Frank Turnbull, Carl F. List, William J. German, A. Earl Walker, J. Grafton Love, Francis C. Grant, I. M. Tarlov, Thomas I. Hoen and Rupert B. Raney

patient with a parasagittal meningioma in whom I had to excise the longitudinal sinus. I controlled the bleeding from the sinus by plastering some fibrin foam over the opening and this became promptly adherent and stopped all bleeding. I have had no occasion to use it on the dura because oozing from the dura is very simply controlled, as a rule, with electric coagulation. I consider the introduction of fibrin foam one of the greatest advances in neurosurgery in recent years. Dr. Bronson S. Ray : I too have found that fibrin foam does everything others have said it

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Axel Olsen and Gilbert Horrax

T he symptomatology of tumors of the cerebellopontine angle, particularly the acoustic neuromas, has been worked out carefully over a period of many years, beginning with the first case history described by Lévéque-Lasource in 1810. 7 Although this may have been a meningioma, the symptoms were well tabulated. The earliest complete story was that given by Cruveilhier 2 in 1835, in his description of a patient who was proved at autopsy to have a tumor of the eighth cranial nerve. Apparently the first diagnosis of an acoustic neuroma in a living patient was

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Arthur D. Ecker and Eugene W. Anthony

revealed bilateral acutely choked discs, tenderness over the anterior part of the right temporal fossa, a central scotoma in the right eye on the confrontation test, and a pulse rate of 52. Roentgenograms of the skull revealed erosion of the floor of the sella, and displacement of the pineal body backward and to the left. The working diagnosis at this time was probable meningioma of the right sphenoidal ridge. However, ophthalmic examination revealed that the visual acuity of the right eye without glasses was 5/200 and with a plus 6.00 sphere was 20/100. The left eye

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Orville T. Bailey and Franc D. Ingraham

from there they extend into the Virchow-Robin spaces. In most instances, the sarcoma lies beneath, and does not penetrate, the arachnoid surface layer. Hence it does not involve the dura primarily and very rarely becomes involved with this structure in the course of its progression. 3, 15 The most frequent tumor occurring in the dura proper is the meningioma. Studies of a series of these tumors 1 have indicated that the meningioma is not of pure fibroblastic origin but is a tumor with stroma. The meningioma arises from arachnoid cells, the source of arachnoid

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Unusual Size and Extension of a Pituitary Adenoma

Case Report of a Chromophobe Tumour with Unusually Extensive Compression of the Base of the Brain, and Review of the Literature on the Pathways of Extension of These Tumours

James C. White and Shields Warren

meningioma growing posteriorly into the sella, or an unusual anterior extension of a pituitary adenoma, was not at first clear. The gross appearance of the tumour suggested the first possibility; the ballooned-out expansion of the sella seen in the x-ray and the upward displacement of the olfactory nerves were in favour of the second. A biopsy was taken and a generous flap of frontal bone cut on the left side to permit a secondary trans-midline exposure, with either resection of the right frontal pole or a midline exposure of the tumour from above by separating the frontal

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Harry S. N. Greene and Hildegarde Arnold

investigation rather than to report a detailed morphological study. MATERIALS AND METHODS The experiments to be described were concerned with an investigation of the transplantability of adult, embryonic and neoplastic brain tissues including the meninges in homologous and heterologous species. The adult and embryonic tissues used in the study were obtained from human, rabbit and guinea pig sources. The neoplastic tissues consisted of an experimentally induced mouse glioma and a number of human tumors, including 5 meningiomas and 3 glioblastoma multiforme. The human