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.3171/jns.1982.56.1.0135 Treatment of nontraumatic atlantoaxial dislocation and fibrous fusion John T. Lucas Gordon D. Hungerford Phanor L. Perot Jr. January 1982 56 1 139 142 10.3171/jns.1982.56.1.0139 Thoracic spinal cord ependymoma presenting with ejaculatory failure Jose Berciano Jaime Gutierrez Mariano Rebollo Guillermo Dierssen January 1982 56 1 143 144 10.3171/jns.1982.56.1.0143 Acromegaly and spinal stenosis Nancy Epstein Margaret Whelan Vallo Benjamin January 1982 56 1 145 147 10.3171/jns.1982.56.1.0145 Lymphocytic adenohypophysitis of pregnancy

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David S. Baskin, Jeannette J. Townsend and Charles B. Wilson

analysis of the surgical specimens revealed lymphocytic adenohypophysitis. Case Reports Case 1 This 33-year-old oriental woman was first seen during her 8th month of pregnancy. She complained of a progressive loss of visual acuity in the left superior temporal field over the preceding 4 weeks. Her medical history included Pott's disease of the spine at 8 years old; treatment consisted of surgical debridement and fusion, and then long-term antibiotic therapy (isoniazid and streptomycin). Preoperative Course . Formal visual field testing on August 13, 1980

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Massimo Scanarini, Domenico d'Avella, Antonino Rotilio, Nicolaos Kitromilis and Salvatore Mingrino

11. McGrail KM , Beyerl BD , Black PM , et al : Lymphocytic adenohypophysitis of pregnancy with complete recovery. Neurosurgery 20 : 791 – 793 , 1987 McGrail KM, Beyerl BD, Black PM, et al: Lymphocytic adenohypophysitis of pregnancy with complete recovery. Neurosurgery 20: 791–793, 1987 12. Nishio S , Mizuno J , Barrow DL , et al : Isolated histiocytosis X of the pituitary gland: case report. Neurosurgery 21 : 718 – 721 , 1987 Nishio S, Mizuno J, Barrow DL, et al

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Turcot's syndrome Hans Peter Rutz Nicolas de Tribolet Jean Marie Calmes Germain Chapuis May 1991 74 5 813 815 10.3171/jns.1991.74.5.0813 Solitary dorsal intramedullary schwannoma Patrick Herregodts Michel Vloeberghs Eric Schmedding Anita Goossens Tadeusz Stadnik Jean D'Haens May 1991 74 5 816 820 10.3171/jns.1991.74.5.0816 Lymphocytic adenohypophysitis presenting as infertility Ian E. McCutcheon Edward H. Oldfield May 1991 74 5 821 826 10.3171/jns.1991.74.5.0821 Percutaneous

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Ian E. McCutcheon and Edward H. Oldfield

1 -weighted images taken before administration of bromocriptine. Sagittal (left) and coronal (right) images through the sella turcica revealing diffuse enlargement of the pituitary gland without focal abnormality. Operation and Postoperative Course Transsphenoidal exploration of the sella revealed an 8-mm well-defined yellowish mass in the anterior lobe of the gland which was removed. Upon pathological examination of this tissue a diagnosis of lymphocytic adenohypophysitis was established. Serum prolactin levels were normal 3 months later and the

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Ramachandra G. Naik, Ariachery Ammini, Pankaj Shah, Chitra Sarkar, Veer Singh Mehta and Manorama Berry

MC , Wilson CB , et al : Lymphocytic adenohypophysitis: a pituitary mass lesion occurring in pregnancy. Proposal for medical treatment. Am J Obstet Gynecol 164 : 1549 – 1555 , 1991 Feigenbaum SL, Martin MC, Wilson CB, et al: Lymphocytic adenohypophysitis: a pituitary mass lesion occurring in pregnancy. Proposal for medical treatment. Am J Obstet Gynecol 164: 1549–1555, 1991 3. Guay AT , Agnello V , Tronic BC , et al : Lympocytic hypophysitis in a man. J Clin Endocrinol Metab 64 : 631 – 634

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Seiji Hama, Kazunori Arita, Takashi Nishisaka, Toshiyuki Fukuhara, Atsushi Tominaga, Kazuhiko Sugiyama, Hiroyuki Yoshioka, Kuniki Eguchi, Masayuki Sumida, Yuji Heike and Kaoru Kurisu

8. Hashimoto K , Takao T , Makino S : Lymphocytic adenohypophysitis and lymphocytic infundibuloneurohypophysitis. Endocr J 44 : 1 – 10 , 1997 Hashimoto K, Takao T, Makino S: Lymphocytic adenohypophysitis and lymphocytic infundibuloneurohypophysitis. Endocr J 44: 1–10, 1997 9. Imura H , Nakao K , Shimatsu A , et al : Lymphocytic infundibuloneurohypophysitis as a cause of central diabetes insipidus. N Engl J Med 329 : 683 – 689 , 1993 Imura H, Nakao K, Shimatsu A, et al

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Michael T. Selch, Antonio A. F. DeSalles, Daniel F. Kelly, Leonardo Frighetto, Harry V. Vinters, Cynthia Cabatan-Awang, Robert E. Wallace and Timothy D. Solberg

pseudotumor (idiopathic orbital inflammation) by radiation therapy. Int J Radiat Oncol Biol Phys 6: 79–86, 1980 7. Feigenbaum SL , Martin MC , Wilson CB , et al : Lymphocytic adenohypophysitis: a pituitary mass lesion occurring in pregnancy. Am J Obstet Gynecol 164 : 1549 – 1555 , 1991 Feigenbaum SL, Martin MC, Wilson CB, et al: Lymphocytic adenohypophysitis: a pituitary mass lesion occurring in pregnancy. Am J Obstet Gynecol 164: 1549–1555, 1991 8. Fitzpatrick PJ , Macko S : Lymphoreticular

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Concurrent lymphocytic hypophysitis and pituitary adenoma

Case report and review of the literature

Shaye I. Moskowitz, Amir Hamrahian, Richard A. Prayson, Mercedes Pineyro, Robert R. Lorenz and Robert J. Weil

✓Lymphocytic hypophysitis (LyH) is an uncommon intrasellar lesion characterized by lymphocytic infiltration of the adenohypophysis. Evidence suggests that the cause is autoimmune, and the symptoms are usually related to either a mass effect or endocrine dysfunction. Lymphocytic hypophysitis has been described rarely in the setting of other simultaneous pathological processes that involve the pituitary and sella turcica, and is postulated to arise from an intrinsic inflammatory response.

The authors report the case of a 43-year-old woman who presented with a 2-month history of galactorrhea and pseudohyperprolactinemia secondary to a 10-mm lesion within an enlarged pituitary gland. She was nulliparous and had no contributory medical history. Serial neuroimaging performed over a 2-year period demonstrated lesion growth, and visual deficits had developed; together these warranted surgical intervention. A transsphenoidal resection was performed. Microscopic and immunohistopathological examinations revealed a nonsecreting pituitary adenoma with concurrent lymphocytic adenohypophysitis.

This is the first documented case of LyH in the setting of a null-cell pituitary adenoma. The authors review the related literature and outline potential mechanisms for the concurrent development of LyH and a pituitary adenoma.

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Mandy J. Binning, Michael T. Walsh, Ronald I. Apfelbaum, Steven S. Chin and William T. Couldwell

infiltrate of benign lymphocytic cells. H & E, original magnification × 100. B: The lymphocytic cell infiltrate is predominantly composed of T cells. Immunoperoxidase with anti-CD3, original magnification × 100. C: A minority of the lymphocytic cells are B cells. Immunoperoxidase stain with anti-CD20, original magnification × 100. This entity has not been described; it appears to be distinct from lymphocytic infundibuloneurohypophysitis and is thought to be distinct from lymphocytic adenohypophysitis, 1 , 2 which primarily occurs in young women and is generally