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Stephen T. Magill, Jacob S. Young, Ricky Chae, Manish K. Aghi, Philip V. Theodosopoulos and Michael W. McDermott

Therefore, determining preoperative risk factors for higher tumor grade can provide useful information for both neurosurgeons and patients. Prior studies have found risk factors for high-grade meningiomas. Male sex and convexity location are known to be associated with increased likelihood of a meningioma being atypical. 19 Although convexity meningiomas are more commonly grade II or III compared to skull base meningiomas, atypical tumors do occur along the skull base. Liang et al. reported that up to 19% of skull base meningiomas were either grade II or III. 19

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Adib A. Abla, David A. Wilson, Richard W. Williamson, Peter Nakaji, Cameron G. McDougall, Joseph M. Zabramski, Felipe C. Albuquerque and Robert F. Spetzler

basal cisterns or fissures. 9 We sought to further study the relationship between aneurysm location and maximum SAH burden in patients enrolled in a prospective randomized controlled trial. In addition to assessing differences in bleed thickness with different aneurysm types, we also investigated whether differences in the location of ruptured aneurysms can further influence the risk for developing symptomatic or radiographic vasospasm. Methods Study Criteria and Data Acquisition We analyzed 250 patients with SAH who had been enrolled in a prospective

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Joung H. Lee, Burak Sade, Eugene Choi, Mladen Golubic and Richard Prayson

; papillary, rhabdoid, and anaplastic meningiomas are considered Grade III tumors. 9 , 15 The prevailing attitude among most neurosurgeons and pathologists is that all benign meningiomas are identical tumors, and that their wide variation in histological appearance has no bearing on the tumor location or on their overall biological behavior. 24 Recently, however, results of our studies and those of other investigators have indicated that the MM is a unique tumor. Shortly after the identification and cloning of the NF2 gene, 23 , 27 we investigated the expression level

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Rashmi Saraf, Manish Shrivastava, Wuppalapati Siddhartha and Uday Limaye

I ntracranial aneurysms are rare in childhood. Various studies have shown that the incidence of intracranial aneurysms in the pediatric age group ranges from 0.5% to 4.6%. 31 , 34 , 36–39 Aneurysms in this age group show different features in terms of etiology, sexual prevalence, location, and morphology. There is male predominance and a higher proportion of aneurysms in the posterior circulation and also a higher frequency of giant aneurysms than in adults. For anterior circulation aneurysms, the most common location is the ICA bifurcation. There are no

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Michael C. Oh, Joseph M. Kim, Gurvinder Kaur, Michael Safaee, Matthew Z. Sun, Anahat Singh, Derick Aranda, Annette M. Molinaro and Andrew T. Parsa

resections are poorly understood. In particular, whether tumor location along the spinal cord conveys any prognostic value is unknown. However, some evidence suggests that tumor location may be more important than tumor grade in determining prognosis. 30 For example, spinal ependymomas generally have a better prognosis than intracranial tumors. 8 , 35 , 58 Thus, further studies identifying the factors important for recurrence and survival are needed to improve current prognosis and management plans, such that surgeons may tailor the aggressiveness of resection to

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Michael C. Oh, Eli T. Sayegh, Michael Safaee, Matthew Z. Sun, Gurvinder Kaur, Joseph M. Kim, Derick Aranda, Annette M. Molinaro, Nalin Gupta and Andrew T. Parsa

E pendymoma arising in the brain or spinal cord is a common CNS tumor in children. 30 Spinal cord ependymoma constitutes only 13.1% of all pediatric ependymomas 24 and is the most common spinal cord tumor, followed by nerve sheath tumors and malignant neuronal/glial tumors. 24 , 37 Spinal cord ependymoma also demonstrates an older age distribution among children, as compared with tumors arising in a supratentorial or infratentorial location. 4 The WHO divides spinal cord ependymoma into 3 histological types: myxopapillary ependymomas and subependymomas

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Yun-Sik Dho, Yong Hwy Kim, Young-Bem Se, Doo Hee Han, Jung Hee Kim, Chul-Kee Park, Kyu-Chang Wang and Dong Gyu Kim

surgical exposure are essential to attaining complete tumor removal with minimal postoperative morbidity. The anatomical locations and extent of craniopharyngiomas play critical roles in planning the surgical approach, and several classifications have previously been introduced to assist in determining the surgical approach. 21 , 29 , 30 The original classification was based on the tumor’s location in relation to the optic chiasm. Recent advances in the endoscopic endonasal approach (EEA), which achieves access through the planum and tuberculum sellae, have led us to

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Ali Sajadi and Nicolas de Tribolet

We present a case of multiple hemangioblastomas of the neuraxis, two of which were found in unusual locations. This 32-year-old woman, with von Hippel—Lindau disease, 1 presented with a few days' history of nausea and on examination a right cerebellar syndrome. Gadolinium-enhanced T 1 -weighted magnetic resonance (MR) imaging demonstrated two right cerebellar nodular cystic hemangioblastomas associated with other nodular lesions of the neuraxis, two of which were of particular interest. The first was located in the intrasellar region, more precisely in the

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Jaime Gasco, Brodus Franklin, Leonardo Rangel-Castilla, Gerald A. Campbell, Mahmoud Eltorky and Paul Salinas

A ngioleiomyomas , also known as “vascular leiomyomas” or “angiomyomas,” are common benign neoplasms most often located within the dermis and subcutaneous tissue of the lower extremities in middle-aged persons, with a predominance among the female sex. 5 , 10 An intracranial site for these tumors is exceedingly rare, with only 4 reports documenting intracranial lesions with locations in the neuraxis, specifically within the region of the cavernous sinus, parietal lobe, internal auditory canal, and caudate nucleus. 4 , 10 , 14 We describe the first case

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Yi-Chieh Hung, Cheng-Chia Lee, Kang-Du Liu, Wen-Yuh Chung, David Hung-Chi Pan and Huai-Che Yang

nerve damage. 3 , 7 , 10 , 24 Although identifying the ideal targeting location is crucial, no consensus on an ideal radiosurgical target for patients with trigeminal neuralgia has been achieved. Most radiosurgeons have administered radiation to the dorsal root entry zone (DREZ), 2 , 4 , 12 , 22 which is generally considered to be the area 3 mm anterior to the location at which the nerve emerges from the pons. 1 According to studies in which the DREZ 2 , 4 , 12 , 22 and the region 2−4 mm from the brainstem 21 were targeted, the initial rates of freedom from pain