Search Results

You are looking at 1 - 10 of 4,654 items for :

  • "infarction" x
Clear All
Restricted access

Benjamin H. Dawson and P. Kothandaram

T he clinical and radiological features and management of five cases of acute massive infarction of pituitary adenoma are briefly set out below. We seek to indicate the diagnostic patterns, to draw attention to the unusual prodrome of severe head cold, nasal catarrh, and persistent cough, and to define the role of surgical and nonsurgical treatment. Case Reports Case 1 This 40-year-old housewife with recognized acromegaly entered the hospital in January, 1958, with a severe head cold, nasal catarrh, persistent cough, headache, neck rigidity, and

Restricted access

Photochemically induced graded spinal cord infarction

Behavioral, electrophysiological, and morphological correlates

Ricardo Prado, W. Dalton Dietrich, Brant D. Watson, Myron D. Ginsberg and Barth A. Green

endothelial damage has been shown to occur following spinal cord injury, 2, 4, 5, 12, 15, 16, 19 with endothelial alterations appearing as early as 90 seconds after impact. Additionally, platelet aggregation and edema formation also appear to be early consequences of impact injury. 1, 2, 12, 13 It is clear that trauma-induced microcirculatory failure and edema formation could result in irreversible damage to the spinal cord. The present study was undertaken to determine if reproducible graded spinal cord infarction could be produced in rats by a recently developed

Restricted access

Joong-Uhn Choi, Harold J. Hoffman, E. Bruce Hendrick, Robin P. Humphreys and William S. Keith

I nfarction of the spinal cord may be encountered in association with dissecting aneurysms of the aorta, 15, 16 as a complication of surgery on the aorta and on the thoracic cavity, 1, 13 in myocardial infarction, 12 in cardiac arrest, 5 and in Stokes-Adams syndrome. 17 It may be due to occlusion of the anterior spinal artery by syphilitic vasculitis, emboli from bacterial endocarditis, periarteritis nodosa, or cholesterol embolus. 11 In 1974, Keith 10 reported on four children with traumatic infarction of the spinal cord who had been treated at The

Restricted access

Mark G. Hamilton, Bruce I. Tranmer and Roland N. Auer

ischemia, are not consistent in the literature. Clinical prospective studies 4, 29 have shown a strong negative prognostic association of hyperglycemia with outcome during acute stroke in humans. 7, 25 Nevertheless, this association has been disputed: one report suggesting that hyperglycemia was correlated with survival only in patients with intracerebral hemorrhage, 36 but not with infarction. Whether hyperglycemia is merely a stress response marker of stroke severity 25, 27, 32, 37 or an elevated blood glucose level itself actually determines a harmful effect has

Restricted access

Raphaël Blanc, Hassan Hosseini, Caroline Le Guerinel, Pierre Brugières and André Gaston

of an embolic agent at the level of the posterior spinal piaarachnoid plexus at the bulbomedullary junction). This complication can be explained by the lack of visualization of anastomoses between the MMA and PMA branches. Surgeons should pay careful attention to the possible reflux of the embolic agent in these anastomoses when treating DAVFs endovascularly. References 1 Bergqvist CA , Goldberg HI , Thorarensen O , Bird SJ : Posterior cervical spinal cord infarction following vertebral artery dissection . Neurology 48 : 1112 – 1115 , 1997 2

Restricted access

Helen M. Haupt, John P. Kurlinski, Nancy K. Barnett and Mel Epstein

infarction may follow thrombosis of the veins of both the spinal cord and the meninges. This results in necrosis of the entire transverse segment, clinically presenting as areflexic flaccid paraplegia and loss of all sensory modalities below the lesion. 8 The clinical presentation of our patient, with the acute onset of total sensory and motor deficits below T-2, is consistent with a vascular insult resulting in total transverse destruction of the spinal cord. While the extent of the lesion is suggestive of venous infarction, the fact that the cord was pale and of normal

Restricted access

Maria Antonia Poca, Bessy Benejam, Juan Sahuquillo, Marilyn Riveiro, Laura Frascheri, Maria Angels Merino, Pilar Delgado and Jose Alvarez-Sabin

M alignant MCA infarction is a devastating disease associated with a high mortality rate (70–80%) and severe disability in survivors when standard medical management is used. 4 , 17 In addition to the extensive amount of necrotic brain tissue involved in malignant MCA infarction, poor neurological outcome occurs because of severe postischemic edema, leading to cerebral herniations, progressive brainstem dysfunction, and intracranial hypertension. Recently, the use of aggressive treatments such as decompressive hemicraniectomy alone or combined with moderate

Full access

Ahmet Arac, Vanessa Blanchard, Marco Lee and Gary K. Steinberg

A mong cases of supratentorial infarction, 10–15% involve the entire MCA territory. 1 , 14 , 22 , 45 Despite optimal medical therapy, the mortality rate approaches 80%. This type of extensive stroke has been termed malignant MCA infarction and is accompanied by severe brain edema, leading to raised ICP and subsequent brain herniation. 11 A vicious cycle develops as the resulting ischemic insult leads to further edema, and thus to increases in ICP and reduction of regional cerebral blood flow. 32 Medical treatment has not been shown to be effective. 16

Restricted access

Juha Öhman, Antti Servo and Olli Heiskanen

its original diameter; moderate for 30% to 50% narrowing; and none to mild for 0% to 30% narrowing of the lumen. Computerized tomography was carried out at 1 to 3 years (mean 1.4 years) after the SAH and surgery. There were no significant differences in the time intervals from SAH to CT scan either between the operation groups (Mantel-Cox test = 0,890, df = 2, p = 0.6408) or between the nimodipine and no-nimodipine groups (Mantel-Cox test = 1.719, df = 1, p = 0.1899). The hypodense areas consistent with infarction were assessed for analytical purposes as absent

Restricted access

Ashok Pillai, Sajesh K. Menon, Satyendra Kumar, Kariyattil Rajeev, Anand Kumar and Dilip Panikar

M iddle cerebral artery infarction often results in significant rates of morbidity and mortality. Although stroke is more common in the elderly, MCA territory infarction is not uncommon in younger age groups because of embolic occlusion, and it accounts for nearly 10% of ischemic strokes. 8 Approximately 10 to 20% of these infarctions are massive and cause severe brain edema resulting in uncal herniation and death. 13 These pathological entities have been referred to as “malignant MCA infarcts.” 8 Medical therapy in such cases is limited to osmotic