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Gilbert Horrax

victims who survived the hemorrhage were destined to various states of spastic paraplegia, usually with seriously impaired mentality, blindness and other evidences of cerebral damage. Cushing was able to report four operative cases with two recoveries from serious subdural hemorrhage in infants from three to eight days old. Subsequently (1910) 15 he reported 12 further cases with recoveries in about half the patients and without the development of spastic paraplegia. In this second article he likewise stated that one of the infants upon whom he had operated in 1905

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Edgar F. Fincher

microcephalus. Many of these publications were controversial but the weight of evidence was that there were arrested developmental cerebral changes in these infants and as such the group did not invite any surgical interest. Freeman 4 in 1927 reported in detail the histologic changes in four cases of microcephalus and these were discouraging for any optimum surgical possibilities. He found “a disordered fat metabolism as a distinctive feature” and “the absence of any inflammatory vascular and degenerative changes striking.” Eley 3 in 1933, in a review of neurologic

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Histologic Studies of the Brain Following Head Trauma

IV. Late Changes: Atrophic Sclerosis of the White Matter

Joseph P. Evans and I. Mark Scheinker

great as in the case of an infant, whose falx is relatively mobile up to the age of about one year. Dyke 2 likewise believed that local dilatation of a ventricle and shift of the intracranial contents occur in an effort to compensate for loss of brain bulk. SUMMARY The pathologic alterations in the brains of seven patients surviving head injuries for variable periods of time up to seventeen years have been analyzed. We have been concerned not with the focal changes associated with cerebral cicatrix but rather with seeking an explanation of diffuse

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James B. Campbell and Eben Alexander Jr.

disease process of which Hand-Schueller-Christian disease is the most insidious and chronic form (occurring in older persons generally) and Letterer-Siwe disease is the most malignant and severe (usually occurring in infants or young children). This concept has received added impetus from Jaffe and Lichenstein 3 who state that in certain stages the lesions of both Hand-Schueller-Christian and Letterer-Siwe disease are indistinguishable from those of a typical early lesion of eosinophilic granuloma. They therefore feel that the three conditions, which show very little

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Paul Weiss

supply problem to be considered. As the freezing-drying procedure does not abolish the biochemical species differential, only human arteries can be used. Aorta furnishes the most suitable sleeve, but only fetal or early infant aorta qualifies in point of size, and since the sleeve must be free of side branches, the yield from a single specimen is rarely more than three pieces. Other types of arteries are less desirable because of their heavy muscular wall. 186 Veins have proved too flabby, at least in animal experimentation. 186, 189 Tantalum Cuffs . It thus became

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Orville T. Bailey and Franc D. Ingraham

relation of dura and tumor. The dark part in the center is the dura. There is a layer of tumor over the outer surface in the entire field while neoplasm is found on the inner surface only on the right half of the field. Hematoxylin and phloxine stain, ×22. Fig. 6. Case 1. General appearance of the tumor in Mallory's phosphotungstic acid-hematoxylin stain. Note the abundance of collagen fibers and the absence of glial elements, ×440. Diagnosis . Fibrosarcoma. Case 2. Hydrocephalic infant 27 days old admitted with diagnosis of subdural hematoma

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Paul C. Bucy and Ben W. Lichtenstein

spinal nerve roots (Lichtenstein 7 ). It is found very frequently in infants suffering from extreme degrees of spina bifida (Arnold, 3 Chiari, 4 Lichtenstein, 7 Schwalbe and Gredig, 10 and Jacob 6 ). Its occurrence in adults has generally been in conjunction with bony anomalies of the craniovertebral junction, such as basilar impression, or platybasia, and fusion abnormalities of the cervical spine (Klippel-Feil's syndrome). Examples of such combinations have been reported by List 8 and by Gustafson and Oldberg. 5 The occurrence of an Arnold-Chiari deformity of

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Michael Scott

cases of cyst of the ventricle of Verga; in one (Case 14) a suboccipital craniectomy was done and at autopsy a dilated cavum pellucidum and cavum of Verga were found. In the second (Case 15) a ventriculogram done on a six week old infant suggested a cyst of the ventricle of Verga. A cerebellar exploration was also done in this infant and adhesions found in the posterior fossa. No histological or necropsy findings were reported. Love, Camp and Eaton (1938) reported a case of symmetrical cerebral calcification, particularly of the basal ganglia, associated with a cyst

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Subdural Hygroma

A Report of Seven Cases

Henry T. Wycis

, xanthochromic or blood-tinged. In the cases analyzed in Table I , the recorded pressures varied from 6 to 15 mm. of Hg. while the protein content varied from 30 to 180 mgm. per cent. SUBDURAL PUNCTURE In this report the group of subdural hygromas occurring in infants is not included. Ingraham and Matson 12 made an excellent study of subdural hematomas and hygromas in infancy and established the diagnostic value of subdural puncture. The technique of the method is fully described in their paper. ROENTGENOGRAPHY A fracture may or may not be present and is

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Curt P. Richter

. , 1929, 88: 596–615. 16. Richter , C. P. Nervous control of the electrical resistance of the skin. Johns Hopk. Hosp. Bull. 1929 , 45 : 56 – 74 . Richter , C. P. Nervous control of the electrical resistance of the skin. Johns Hopk. Hosp. Bull. 1929, 45: 56–74. 17. Richter , C. P. High electrical resistance of the skin of new-born infants and its significance. Amer. J. Dis. Child. , 1930 , 40 : 18 – 26 . Richter , C. P. High electrical resistance of the skin of new-born infants and its