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Mason Trupp and Ernest Sachs

steppage gait. Vibratory sense in both legs gone. Lumbar puncture: Yellow fluid which coagulated (Froin's syndrome). Complete block on Queckenstedt. “This is probably a conus tumor, might be a giant tumor of cauda.” Operation . Laminectomy from D10 down. On opening the dura, the cord herniated enormously. A vascular tumor, 5 to 6 inches long, lay in front of the cord. Tumor was an angioma and contained numerous thrombi. It was not coagulated but removed by clipping vessels. Diagnosis: Angioma of cord. Case 21 . G.R., female, aged 36 (B.H. No. 54497). Referred by

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Paul Teng and Christos Papatheodorou

evidence of intracranial calcification. ( Right ) Deposition of air over surface of tumor prior to the first operation in 1960. Note lobulated appearance of the giant tumor and no evidence of intracranial calcification. On Jan. 8, 1962, at the age of 4, the patient was readmitted for diagnostic studies. Lumbar puncture demonstrated normal pressure and clear cerebrospinal fluid containing a total of 80 mg. protein per cent. A percutaneous left carotid arteriogram disclosed a bowing anterior cerebral artery embracing the shadow of calcification without a lateral

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Paul R. Cooper, Gleb N. Budzilovich, Peter H. Berczeller, Abraham Lieberman and Arthur Battista

. There were numerous areas of necrosis and a moderate degree of vascular hyperplasia ( Fig. 2 left ). The latter component consisted of medium sized sheets and only moderately pleomorphic cells which characteristically “shunned” the blood vessels. Fig. 2. Case 2. Left: Photomicrograph of tumor removed in October, 1970, shows a slightly anaplastic astrocytoma with pleomorphism and giant tumor cells. H & E, × 125. Right: Photomicrograph of vertebra, 1972. The bone marrow spaces are filled by a poorly cellular tumor tissue. The bony trabeculae have irregular

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Donald L. Erickson, James I. Ausman and Shelley N. Chou

encountered this situation in nine patients. We have elected to treat these patients without resorting to nerve anastomosis or facial plastic surgery. We define an acoustic tumor as large if the brain stem is indented, the fifth nerve stretched over the superoanterior pole, and the ninth and tenth nerves stretched under the inferior pole. That would imply a minimum tumor size of perhaps 3 cm in diameter. The tumors in this series ranged from 3 cm to a giant tumor of 7 or 8 cm in diameter. This paper presents our experience with the recovery of seventh nerve function in

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Subependymal giant-cell astrocytoma

Case report with ultrastructural study

Anders A. F. Sima and David M. Robertson

micrograph of a giant tumor cell with abundant cytoplasm containing numerous mitochondria and endoplasmic reticulum profiles (dilated). Numerous dense bodies can be seen in the cytoplasm measuring 350 to 900 nm. The nucleus is infolded with a prominent nucleus. × 5200. Inset: Desmosomal junctions between cell body and processes are indicated by arrows . × 24,480. Fig. 4. Electron micrograph showing dense irregular Rosenthal fibers in the cell processes of the tumor cells. × 13,800. The cytoplasm contained numerous membrane-bound electron-dense bodies

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Acoustic neurilemmoma

Clinicoanatomical study of 103 patients

Vira Kasantikul, Martin G. Netsky, Michael E. Glasscock III and James W. Hays

73 4 21 15 1.1–2.0 (medium) 14 42 19 58 33 2.1–4.0 (large) 11 32 23 68 34 4.1–6.5 (giant) 7 33 14 67 21 total 43 60 103 Analysis of size of tumor and number of tumor cells revealed that intracanalicular masses most often had intense cellularity ( Table 4 ). Most extracanalicular tumors of medium or large size were moderately cellular. Giant tumors overwhelmingly had moderate cellularity, and were never intensely cellular. TABLE 4 Size and degree of cellularity of tumor

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side. 2 Splitting of the splenium of the corpus callosum was done in over 32 explorations for posterior third ventricular tumor, and in 17 patients with pinealoma no disconnection syndrome was observed. 1 The extent of the division of the corpus callosum for meningiomas of the lateral ventricles is no larger than in the aforementioned procedures. The use of the Cavitron ultrasonic instrument adds safety to the removal of even giant tumors closely adherent to the periventricular white matter. The size of a tumor is no contraindication to a midline approach. The

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Malignant fibrous histiocytoma of the meninges

Histological, ultrastructural, and immunocytochemical studies

Uma P. Kalyanaraman, John J. Taraska, Joshua A. Fierer and Patrick W. Elwood

from the absorption of these hemorrhages, hemosiderin-filled macrophages, and numerous endothelial-lined blood vessels were also prominent. The underlying brain tissue showed focal islands of spindle-shaped cells with some astrocytic response in the adjoining tissue. The intervening brain tissue was otherwise free of tumor. The Virchow-Robin spaces around the blood vessels also contained tumor cells ( Fig. 4 ). Fig. 2. Photomicrographs showing pleomorphic spindle cells in a cartwheel or storiform pattern. H & E. Left: Giant tumor cells are indicated (arrow

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Paul Steinbok, Clarisse L. Dolman and James H. Goldie

and not epithelial. Examination of the specimen from the cervical mass obtained at aspiration in July, 1981, yielded clumps and a diffuse scatter of anaplastic cells similar to those seen in the lymph node section. Fig. 1. Lymph node biopsy specimen. Left: Photomicrograph of the metastatic tumor showing sheets of small, undifferentiated cells, among which lie occasional multinucleated giant tumor cells. H & E, × 383. Right: Electron micrograph of the same specimen. The tumor cells have irregular nuclei, often with prominent nucleoli, and angular or

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Michel Djindjian, Patrick Ayache, Pierre Brugières, Denis Malapert, Marielle Baudrimont and Jacques Poirier

presentation as a giant tumor of the cauda equina. This case arose from the intradural filum terminale, and was identified as gangliocytic by histological and ultrastructural studies. Case Report This 36-year-old man was admitted to the emergency department in December, 1986, because of sudden paraplegia following sacral infiltration of medication for treatment of a low-back pain. Metrizamide myelography with lateral cervical infusion and computerized tomography showed a complete block at the L-2 level with moderate vascular filling defects suggestive of an ependymoma