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Claude C. Coleman

injuries that present the greatest problems as to treatment are those in which there is complete reaction of degeneration. Electrodiagnosis in its usual application is merely confirmatory of the more important clinical history and findings. Study of the nerve at exploration by the faradic current applied to the nerve above the lesion may give important diagnostic information. If application of the electrode above the injury produces contraction of the muscle supplied by the nerve, obviously one would not remove a neuroma in continuity. However, if there is no response in

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W. K. Welch and Margaret A. Kennard

callosum had been injured by the right ablation. The basal ganglia were grossly intact. The parietal lesion on the left did not involve area 4 or subcortical structures. Subsequent histological examination confirmed these findings. It further revealed scattered and sparse, but definite degeneration in the sciatic nerves. Summary . A large male mangabey, following bilateral removal of areas 6 and 4s, showed reflex grasp, increased resistance to extension of all extremities and a posture of flexion, adduction and internal rotation of the lower extremities and flexion of

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Histologic Studies of the Brain Following Head Trauma

IV. Late Changes: Atrophic Sclerosis of the White Matter

Joseph P. Evans and I. Mark Scheinker

greater part of the cortex appeared completely destroyed and replaced by large masses of gitter cells in a dense network of newly formed capillaries. It was of interest that in areas distant from the softening the vessels appeared congested and disclosed signs of stasis and prestasis. The perivascular spaces were distended and the adjacent tissue appeared rarefied and edematous. Many of the nerve cells were lost while others showed severe cell changes and ischemic degeneration. Sections stained with phosphotungstic acid disclosed an increase in fibrous tissue

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Paul Weiss

Proximal Stump . That part of a severed nerve left connected with the centers. Distal Stump . That part of a severed nerve disconnected from its centers. Aneuritic 109 Nerve . Nerve after degeneration of all axons. Gap . The space between the cut faces of two nerve stumps. Union Tissue . The tissue filling the gap and interweaving the formerly separated stumps. Matrix . The non-cellular foundation of the union tissue. Scar . Union tissue with excessive fibrous development. Junction . The level at which the nerve stumps are reconnected, which after

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R. A. Groat, W. F. Windle and H. W. Magoun

. Infection and malnutrition in the animals restrained the author from reporting any observations except some Marchi degeneration. METHODS AND MATERIAL Physiologic studies were conducted in acute experiments on 7 rhesus monkeys lightly anesthetized with chloralosane. Only mild concussion could occasionally be produced by means of the pendulum or the hydraulic apparatus previously used on cats. Force applied by either method sufficient to kill a cat would not affect a monkey. Rather than add weight to the pendulum and incur the risk of fracturing the skull, the piston

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I. M. Tarlov and J. A. Epstein

homologous nerve (sciatic nerve graft for repair of a gap in the sciatic nerve) taken, in fact, from the same level of the nerve. Thereby one can to some extent at least match fasciculi of the graft and the host stumps in a rough way. However, as an actual fact, much distortion of the internal relationships occurs within the graft as a result of its nerve fiber degeneration and fibrous proliferation so that the theoretical advantage is thereby largely negated. The use of single thin grafts for the repair of defects in the digital nerves is associated with satisfactory

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Marcus Singer

with various methods of suture at 7 to 8 days. 2, 7 This delay has been attributed to ascending or traumatic degeneration of the fibers of the proximal stump followed by their regeneration to the level of the wound and their subsequent growth through the scar. In order to test the influence of fibrin adhesive upon this latent period, the distance of growth of fibers through the distal stump was measured 13 to 20 days after operation in a series of rabbits. From these readings the delay was calculated by assuming a constant rate of neuronal growth in the distal stump

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R. Glen Spurling, W. R. Lyons, B. B. Whitcomb and Barnes Woodhall

Army in the World War. Washington : Govt. Printing Office , 1927 , 11 : 1091 – 1283 . Huber , G. C. Experimental observations on peripheral nerve repair. In: The Medical Department of the United States Army in the World War . Washington: Govt. Printing Office, 1927, 11: 1091–1283. 7. Sanders , F. K. , and Young , J. Z. The degeneration and re-innervation of grafted nerves. J. Anat. Lond. , 1942 , 76 : 143 – 166 . Sanders , F. K., and Young , J. Z. The degeneration and re-innervation of grafted nerves

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E. S. Gurdjian and H. M. Smathers

in its normal position below and above the lesion, with further dissection at the site of pathological change. After freeing the nerve it was transposed into a live muscle bed. If the nerve had undergone neuromatous degeneration neurolysis was performed, and if the individual bundles, although swollen at the site of trauma, were still patent the nerve continuity was not disturbed ( Fig. 4 ). If the nerve was found sectioned, it was sutured in the usual manner ( Figs. 2 and 3 ). Fig. 4. Neuromatous degeneration in a case of radial palsy with fracture of

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I. Mark Scheinker

showed definite signs of compression and neuronal degeneration. Fig. 3. Case 1. At the tumor base the neoplastic cells gradually blended through transitional cell forms with the normal elements of the subependymal glia. Note the similarity between the neoplastic cells and those of the normal subependymal glia. Hematoxylin eosin stain (×165). Case 2 . C.K., a 53-year-old woman known to have arterial hypertension, was admitted to the hospital in an unconscious state. In the last few days prior to admission she complained of severe occipital headache and