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Thomas A. Duff and Ross Levine

craniopharyngioma was found exclusively within the chiasm, presumably due to direct penetration from the hypophyseal stalk. Case Report Five years prior to admission, this 56-year-old male welder had been evaluated at another hospital for visual deterioration following a minor head injury. Ophthalmological examination at that time revealed a bitemporal hemianopsia, with visual acuity in the right eye of 20/30 and in the left eye of 20/60. Computerized tomography (CT) of the head, cerebral angiography, and pneumoencephalography were interpreted as normal, and the visual

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Behrooz Azar-Kia, Uttamapalayam R. Krishnan, and Mannie M. Schechter

C raniopharyngioma is a rare neonatal tumor; only three cases have been reported in the English literature. Two of these showed large areas of suprasellar calcification, 1, 3 while a third revealed no calcification; 2 all manifested obstructive hydrocephalus. We are reporting a case of a neonatal craniopharyngioma which presented unusual features. Case Report This baby boy was delivered by Caesarean section after 37 weeks of gestation because of cephalopelvic disproportion noted in the pelvimetric films. He had an Apgar score of 2 at 1 minute and 6 at

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Heshmatolah Majlessi, Ahmad S. Shariat, and Abdolali Katirai

C raniopharyngiomas produce striking and typical symptoms by compression of the optic pathways, pituitary, and hypothalamus. Direct invasion of brain parenchyma is exceedingly rare, 1, 2 and nasopharyngeal extension of a craniopharyngioma is also uncommon. 3–5 This is the report of a case of craniopharyngioma with extension into the orbits, nasopharynx, and oropharynx. Case Report This 17-year-old boy was referred to the University of Isfahan Medical Center for radiation therapy of a very large and unusual craniopharyngioma. He appeared chronically ill

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Nur Altinörs, Engin Şenveli, Ahmet Erdoğan, Nuri Arda, and Işin Pak

C raniopharyngiomas account for approximately 2% to 3% of all intracranial tumors. 21, 22 They are mainly considered to be suprasellar tumors. We are reporting a case of craniopharyngioma in a very unusual anatomic location, and consequently associated with very different clinical manifestations. Case Report This 14-year-old boy was hospitalized for evaluation of progressive loss of hearing in the right ear for 2 years. In addition, he had complaints of diplopia and pain in the neck radiating over the shoulders. Examination The physical

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Dae Kyu Lee, Hee-Won Jung, Dong Gyu Kim, Sun Ha Paek, Ho-Shin Gwak, and Gheeyoung Choe

ectopic recurrence in the cranial cavity have been reported. 1, 5, 6, 8, 10, 12, 14 The authors present a case of postoperative spinal seeding of a craniopharyngioma of the papillary histological type, which is usually encountered in adults as a solid noncalcified mass, often within the third ventricle, in contrast with the adamantinomatous type. 2 No spinal seeding of either papillary or adamantinomatous craniopharyngiomas has been reported previously. Case Report First Admission History This 26-year-old man was admitted with headache and decreased

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Ashvin T. Ragoowansi and David G. Piepgras

I n 1904, Erdheim 5 carefully detailed the histological features of craniopharyngiomas and postulated that they originated from embryonic squamous cell rests of an incompletely involuted hypophyseal-pharyngeal duct. 3 Since then, these tumors have challenged the skill of neurosurgeons and have stimulated controversy regarding the ideal therapeutic approach. While total removal of the tumor is the most desirable operative goal, unacceptable morbidity and poor quality of survival, especially for patients with large tumors treated in the premicrosurgical era

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Erin N. Kiehna and Thomas E. Merchant

I n 1932, Harvey Cushing described craniopharyngioma as “the most baffling problem which confronts the neuro-surgeon.” 6 In 2 detailed accounts, he described performing frontal craniotomies for cystic fenestration of these lesions, only to have to return for subsequent fenestration and cystic resection due to symptomatic cystic recurrence. 21 , 40 The treatment of craniopharyngioma remains equally challenging and controversial in 2010. Although craniopharyngioma is pathologically benign in children, and should be curable by complete surgical removal, the

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Péter Banczerowski, Katalin Bálint, and László Sipos

T he postoperative occurrence of ectopic craniopharyngiomas by direct mechanical transplantation or meningeal seeding is a recognized phenomenon. 2 , 5 Nevertheless, histologically confirmed primary craniopharyngioma at an ectopic location is rare, although cases of epidural and even extracranial neoplasms have been reported in sphenoid bone, ethmoid sinus, and the nasopharyngeal region, 3 and intracranially in the corpus callosum, third ventricle, or pineal region. 4 , 7 We report a histologically confirmed primary craniopharyngioma that arose at an

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Radical excision of craniopharyngioma

Results in 20 patients

Lindsay Symon and William Sprich

T he term “craniopharyngioma” was first used in 1931 by Frazier and Alpers 7 and by Cushing in 1932. 6 The first detailed autopsy account of such a tumor was given in 1857 by Zenker, 28 when he described a cystic suprasellar lesion containing cholesterol crystals and squamous epithelium. Further histological evidence for the tumor which we today call “craniopharyngioma” was given 3 years later by Luschka 15 in his description of squamous epithelial cells in the region of the infundibulum. Over the years, a number of other terms have been used to describe

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Craniopharyngiomas in childhood

A rational approach to treatment

Kenneth Shapiro, Kenneth Till, and D. Norman Grant

T he benign microscopic appearance of craniopharyngiomas belies their malignant clinical behavior in childhood. These extracerebral tumors often insinuate themselves into adjacent structures, making operative removal hazardous and often incomplete. In spite of this growth pattern, the availability of exogenous hormones has stimulated some surgeons to attempt radical removal of these tumors. 1, 7 Others, mindful of the dangers of operation and encouraged by the apparent responsiveness of craniopharyngiomas to x-ray therapy, have advocated limited surgical