Search Results

You are looking at 1 - 10 of 442 items for :

  • "chondrosarcoma" x
  • All content x
Clear All
Restricted access

Mark Bernstein, Richard G. Perrin, Marjorie E. Platts, and William J. Simpson

R adiation-induced sarcoma is a rarely encountered intracranial neoplasm. Most reports in the literature have described fibrosarcomas arising after irradiation of pituitary tumors, 4, 8, 28 but irradiation of other intracranial neoplasms has also been followed by the occurrence of sarcoma. 2, 3, 18, 23 We were unable to find a report in the literature of radiation-induced chondrosarcoma of the brain and we therefore present this unique case and the interesting pathology encountered. Case Report This 24-year-old man was admitted on November 2, 1977

Restricted access

David K. Zucker and Dikran S. Horoupian

M esenchymal chondrosarcoma is a rare malignant tumor. It was first described arising from bone by Lichtenstein and Bernstein in 1959, 14 and was later reported as a primary tumor in extraosseous tissues. 9 The tumor shows proliferation of primitive mesenchymal cells with islands of cartilagenous differentiation. Dahlin and Henderson 3 were the first to note that in some areas the tumor had features of hemangiopericytoma. This resemblance was later stressed by others, 6, 9, 23 and some tumors originally diagnosed as hemangiopericytoma with cartilaginous

Restricted access

Russell L. Blaylock and Ludwig G. Kempe

P rimary malignant tumors of the bone involving the vertebral axis are extremely rare. Of this group of osseous tumors, the chondrosarcoma has been reported to involve the vertebral axis in less than a dozen cases. We are presenting a case of chondrosarcoma primarily involving the lateral mass of the C-2 vertebra. Case Report This 43-year-old man had been in good health until early in 1971, when he began to have recurring left suboccipital headaches; over a period of 1 month these became persistent. He was seen by a neurosurgeon at that time and was

Restricted access

Takatoshi Sorimachi, Osamu Sasaki, Shinji Nakazato, Tetsuo Koike, and Hiroyuki Shibuya

P rimary cranial myxoid chondrosarcomas are rare neoplasm that usually arise in the skull base. 1–4 , 6 , 7 , 9–12 Only 6 cases of primary intracranial extraosseous myxoid chondrosarcoma have been previously reported, 5 , 8 , 13–16 and 5 of the lesions were attached to the dura mater or the choroid plexus. 5 , 13–16 We report a case of myxoid chondrosarcoma of the pineal region without any attachment to the meninges or the choroid plexus. This is the second reported case of intracranial myxoid chondrosarcoma without attachment to the meninges or the

Restricted access

Julie E. York, Rasim H. Berk, Gregory N. Fuller, Jasti S. Rao, Dima Abi-Said, David M. Wildrick, and Ziya L. Gokaslan

P rimary chondrosarcoma of the spine is an extremely rare tumor, and only 21 patients with this condition have been treated at The University of Texas M. D. Anderson Cancer Center as of 1997. In such patients, the roles of various treatment options, namely surgical excision, radiation therapy, and chemotherapy, have not been well established. Although surgical excision has been advocated as the primary mode of therapy for treating patients with chondrosarcoma, the role of an aggressive surgical approach has not been well documented. The purpose of this study

Restricted access

H. Alan Crockard, Anthony Cheeseman, Timothy Steel, Tamas Revesz, Janice L. Holton, Nicholas Plowman, Anoushka Singh, and John Crossman

C hondrosarcomas are malignant tumors composed of cartilage-producing cells that are rarely encountered in the skull base and represent 0.15% of all intracranial tumors. Approximately 50% of these tumors arise along the base of the skull where the chondrocranium is formed. During ossification, focal areas of cartilage remain unchanged and these cartilaginous rests may be the progenitors of chondrosarcomas, allowing them to arise in the petrous apex, the posteromedial temporal bone, and between the internal acoustic meatus and the jugular foramen. A few of

Restricted access

Juan J. Martin, Ajay Niranjan, Douglas Kondziolka, John C. Flickinger, Karl A. Lozanne, and L. Dade Lunsford

A lthough generally slow growing, skull base chordomas are locally aggressive and destructive tumors with high recurrence rates. These uncommon tumors are thought to arise from remnants of the notochord. Such remnants may persist anywhere along the neuraxis; however, the sacrum and clivus are the most frequent sites. 12 , 28 Chondrosarcomas originate from primitive mesenchymal cells within the cartilaginous matrix of the skull base. 12 The imaging features and clinical presentations of patients harboring either chordomas or chondrosarcomas are similar

Free access

Paulo M. Mesquita Filho, Leo F. S. Ditzel Filho, Daniel M. Prevedello, Cristian A. N. Martinez, Mariano E. Fiore, M.D., Ricardo L. L. Dolci, Bradley A. Otto, and Ricardo l. Carrau

recently become a tool of interest in skull base surgery, offering a direct anterior approach to these lesions, which allows adequate resection while minimizing surgical morbidity. Likewise, the ability to access multiple compartments, remove infiltrated bone, and achieve tumor resection without the need for neural retraction makes EEAs particularly appealing in the management of these complex lesions. We advocate the use of EEAs as the initial surgical corridor in all cases of petroclival chondrosarcomas, since the origin of these lesions is the petroclival

Restricted access

Robert M. Crowell and James G. Wepsic

P atients with hereditary multiple exostoses rarely develop chondrosarcomas 1, 4 or spinal cord compression. 3–7, 9, 10, 12, 13 The literature contains a single case of cord compression by a pathologically documented chondrosarcoma in a patient with multiple exostosis. 8 We now present two cousins with multiple exostoses and chondrosarcoma producing thoracic spinal cord compression in the second decade of life. Case Reports Case 1 A 13-year-old boy was admitted to the Massachusetts General Hospital on August 6, 1970, because of progressive

Restricted access

Toshinori Hasegawa, Dai Ishii, Yoshihisa Kida, Masayuki Yoshimoto, Joji Koike, and Hiroshi Iizuka

S kull base chordomas and chondrosarcomas are rare tumors, each accounting for less than 0.2% of all intracranial neoplasms. 1 , 6 , 11 , 14 , 15 , 22 , 24 Although resection is the most common treatment for these tumors, complete resection is still challenging even for experienced neurosurgeons, despite advanced microsurgery and skull base techniques. These tumors are locally aggressive, infiltrating the bone and surrounding soft tissue adjacent to critical structures such as major vessels and cranial nerves. 13 , 27 Therefore, most patients with