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Jason P. Sheehan, John A. Jane Jr., Dibyendu K. Ray and Howard P. Goodkin

. Although advances in head imaging resulted in an initial decline in the mortality rate, children with brain abscesses do remain at risk for death. 1 , 9 , 10 , 23 , 25 Early diagnosis combined with the prompt initiation of empirical broad-spectrum antimicrobial therapy and neurosurgical intervention are important components in the care and treatment of children with brain abscesses. Brain abscesses in children are rare. 12 , 15 At the University of Virginia Children's Hospital for the years 2000–2007 (inclusive), an average of 1.5 children per year was admitted to

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Forniceal glioma in children

Clinical article

Thomas Blauwblomme, Pascale Varlet, John R. Goodden, Marie Laure Cuny, Helene Piana, Thomas Roujeau, Federico DiRocco, Jacques Grill, Virginie Kieffer, Nathalie Boddaert, Christian Sainte-Rose and Stéphanie Puget

function. 1 , 2 , 4–6 We report a series of 8 children treated in the Hôpital Necker Enfants Malades, Paris, over a 17-year period. Their presentation, disease management, histological and radiological features, and outcomes are described. Methods We performed a retrospective analysis of all children who were treated surgically at Hôpital Necker for supratentorial glioma between 1990 and 2007. There were 250 patients, with only 8 having lesions involving the fornix. We excluded large tumors from other locations with forniceal extension. Histological findings

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Sandro Mercuri, Antonio Russo and Lucio Palma

E very neurosurgeon is familiar with the concept of cystic tumors of the cerebral hemispheres with a benign course in children, but few authors have focused their attention on such tumors. 6, 10–12, 16 In 1962, Gol 4 made a close study of the prognosis of hemispheric supratentorial astrocytomas (HSA) in children, and compared their prognosis to that in adults. 5 The purpose of this study is to analyze the long-term results in 29 cases of HSA in children who were operated on over a 28-year time span and followed for periods ranging from 5 to 27 years

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Intraspinal tumors in children

A review of 81 cases

Alonso L. DeSousa, John E. Kalsbeck, John Mealey Jr., Robert L. Campbell and Arthur Hockey

I ntraspinal tumors are relatively rare in childhood. Stookey 21 had only eight cases at the New York Neurologic Institute between 1910 and 1926, and Ingraham 14 reported 16 cases at Boston Children's Hospital from 1918 to 1938. In 1944, Hamby 12 reviewed the literature and found 214 cases. Grant and Austin 10 in 1956 reported 30 cases of spinal cord tumors in children under the age of 15 years from a total of 409 cases in all age groups (7.3% of the cases). In 1969, Matson 17 compiled a series of 134 primary intraspinal tumors in children. More recently

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Arthur E. Marlin, Gayle R. Williams and J. Fletcher Lee

I n 1920, Geoffrey Jefferson 3 reported 46 cases of fractures of the atlas. Included among these were four of his own cases. This fracture, which now bears his name, is exceedingly unusual in children. Indeed, Jefferson's report from Sir Astley Cooper in 1822 2 is the only one to be found in the literature. This case is reprinted here as it is not readily accessible, and a new case in a 2-year-old is presented. Case Reports Case 1 This report is reproduced verbatim from Cooper's description. 2 “A boy, about three years of age, from a severe fall

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Craniopharyngiomas in children

Long-term effects of conservative surgical procedures combined with radiation therapy

Edwin G. Fischer, Keasley Welch, John Shillito Jr., Ken R. Winston and Nancy J. Tarbell

increasing number of reports of equally successful in situ irradiation of craniopharyngiomas. 2, 10, 13, 16, 18, 25 The risk of death from various causes and of tumor recurrence for both types of treatment has become more clearly defined as longitudinal patient follow-up periods have increased. Patients can often compensate for neurological and endocrine deficits, unlike psychosocial deficits which have become recognized as major factors limiting quality of life as patients grow into adulthood. 6, 7, 11, 15 We have followed 37 children who were consecutively treated

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Seung-Ki Kim, Kyu-Chang Wang, Yong-Seung Hwang, Ki Joong Kim, Jong Hee Chae, In-One Kim and Byung-Kyu Cho

E pilepsy surgery is a viable option for intractable epilepsy, which comprises 10–20% of the cases of pediatric epilepsy. 14 , 18 Experience derived from such surgery shows that children present with different features than adults. Children have a higher proportion of neoplastic and malformation lesions in the epileptogenic substrate and more frequent extratemporal foci of epileptogenesis, and they require surgical treatment of the developing brain. 8 , 11 , 14 , 15 , 19 , 27 Evaluation of surgical outcome and complications is important when selecting

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Edwin G. Fischer, Keasley Welch, James A. Belli, James Wallman, John J. Shillito Jr., Ken R. Winston and Robert Cassady

T here are some proponents for either radical excision 20, 28, 41, 46 or irradiation 7, 24, 25, 38 as the preferred therapy for craniopharyngiomas in children. The risks and benefits of each method of treatment are not fully defined and remain a matter of continued investigation. We are reporting our experience with 37 children with craniopharyngioma who received a major part of their treatment at Children's Hospital, Boston, between 1972 and 1981. Patients who were seen in consultation but who did not receive any treatment were excluded. The therapeutic

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Dominique Figarella-Branger, Muriel Civatte, Corine Bouvier-Labit, Joany Gouvernet, Danielle Gambarelli, Jean-Claude Gentet, Gabriel Lena, Maurice Choux and J. F. Pellissier

E pendymal tumors represent fewer than 9% of all neuroepithelial neoplasms. 29 According to WHO, 18 four major subtypes occur, including ependymoma, anaplastic (malignant) ependymoma, myxopapillary ependymoma, and subependymoma. Ependymal tumors may be observed in three major locations: the supratentorial compartment, the posterior fossa, and the spinal cord. The prognosis for patients with intraspinal tumors is most favorable. 7 Ependymomas account for 6 to 12% of brain tumors in children and represent the third most common central nervous system neoplasms

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George J. Dohrmann, Jacqueline R. Farwell and John T. Flannery

D pendymomas and ependymoblastomas arise from the cells lining the cerebral ventricular system and the central canal of the spinal cord. Approximately half of all of these tumors occur in children ( Table 1 ) and account for one-tenth of intracranial neoplasms of childhood ( Table 2 ). The presentation and clinical course of these childhood ependymal neoplasms are incompletely understood. TABLE 1 Incidence of ependymal neoplasms in children reported in 10 series Author, Year Total Cases Children No. % Kernohan