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Takamitsu Fujimaki, Masao Matsutani, Akio Asai, Takeshi Kohno and Morio Koike

C erebral venous thrombosis due to polycythemia has rarely been reported. It is well known that cardiopulmonary collapse, cerebral edema, and thrombophlebitis of the extremities are common in climbers at high altitudes. 8, 9, 11 However, no pathologically confirmed case of cerebral venous thrombosis has previously been reported in this group of individuals. We report a case of cerebral venous thrombosis as a complication of polycythemia secondary to adaptation to a high altitude. Case Report This 27-year-old previously healthy man climbed from Kathmandu

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J. Nicole Bentley, Ramón E. Figueroa and John R. Vender

must be knowledgeable about the current methods of diagnosis and treatment of CVT. 6 Patients will often present initially to a stroke service, but neurosurgeons are often consulted for increasing ICP or hemorrhagic infarcts. Additionally, patients in whom conservative treatment with anticoagulation fails may need surgical intervention. 49 Cerebral venous thrombosis predominantly affects young people who are otherwise healthy, and women are affected more often than men. 10 Risk factors are varied, but virtually any medical condition that causes hypercoagulability

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Stylianos K. Rammos, Jayme Phillips, Julian Lin, Kenneth Moresco and Sean Meagher

. Cerebrovasc Dis 15 : 159 – 166 , 2003 2 Carvalho KS , Bodensteiner JB , Connolly PJ , Garg BP : Cerebral venous thrombosis in children . J Child Neurol 16 : 574 – 580 , 2001 3 Chow K , Gobin YP , Saver J , Kidwell C , Dong P , Viñuela F : Endovascular treatment of dural sinus thrombosis with rheolytic thrombectomy and intra-arterial thrombolysis . Stroke 31 : 1420 – 1425 , 2000 4 Dowd CF , Malek AM , Phatouros CC , Hemphill JC III : Application of a rheolytic thrombectomy device in the treatment of dural sinus

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Si Zhang, Hexiang Zhao, Hao Li, Chao You and Xuhui Hui

.270 0.776 (0.495–1.217) Hemorrhage-dominated lesion 0.026 6.255 (1.240–31.547) Bilat lesions 0.182 4.177 (0.512–34.053) Deep cerebral venous involvement 0.026 16.254 (1.396–189.321) Discussion Cerebral venous thrombosis is an uncommon but potentially life-threatening stroke with unique features. 18 Although the general outcome of CVT is favorable, 11 severe CVT can cause progressive intracranial hypertension resulting in brain herniation. 3 For patients with impending herniation, DC may be the only life-saving treatment. However, the current guidelines do not

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Avital Perry, Christopher S. Graffeo, Waleed Brinjikji, William R. Copeland III, Alejandro A. Rabinstein and Michael J. Link

common headache etiologies is attempted. 39 For most patients with SIH, this results in prolonged discomfort, but minimal clinical impact, as complications are rare, and the condition ultimately responds well to treatment via epidural blood patch (EBP). 29 However, severe complications of SIH have been reported, including cerebral venous thrombosis (CVT). 12 , 21 , 22 , 25 , 42 , 43 Although estimated to occur in just 2% of SIH cases, CVT may quickly precipitate life-threatening complications including intracranial hemorrhage, seizures, brain herniation, venous

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Dag Ferner Netteland, Magnus Mejlænder-Evjensvold, Nils O. Skaga, Else Charlotte Sandset, Mads Aarhus and Eirik Helseth

E merging literature suggests that traumatic brain injury (TBI) may be an important etiology of cerebral venous thrombosis (CVT). 1 However, apart from multiple case reports and small case series, the literature on CVT in the setting of TBI is scarce. Pathophysiologically, thrombosis of cerebral dural venous sinuses leads to obstructed venous drainage, resulting in increased hydrostatic pressure in upstream veins and capillaries. 2 This in turn can lead to complications of CVT in the form of parenchymal edema, decreased arterial perfusion causing venous

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Matthew F. Philips, Linda J. Bagley, Grant P. Sinson, Eric C. Raps, Steven L. Galetta, Eric L. Zager and Robert W. Hurst

F erebral venous thrombosis results from thrombosis of cortical and deep veins and/or intracranial venous sinuses. The spectrum of signs and symptoms connected with cerebral venous thrombosis may be broad; it is associated with a variety of conditions, including infection, coagulation disorders, chronic inflammatory disease, and trauma. If the disease is unrecognized, a delay in treatment may result in cerebral edema, intracranial hypertension, cerebral ischemia, and hemorrhagic infarction, resulting in rapid neurological deterioration, coma, and even death. 6

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Michel Roethlisberger, Lara Gut, Daniel Walter Zumofen, Urs Fisch, Oliver Boss, Nicolai Maldaner, Davide Marco Croci, Ethan Taub, Natascia Corti, Jan-Karl Burkhardt, Raphael Guzman, Oliver Bozinov and Luigi Mariani

waived the need for obtaining written informed consent. This study is a retrospective analysis of preexisting data without intervention and therefore does not require clinical trial registration. One author (L.G.) conducted retrospective patient chart review for both centers. Inclusion and Exclusion Criteria Female patients with diagnosed cerebral venous thrombosis (CVT) of the dural sinuses, involvement of the deep venous system (DCVT), cortical venous thrombosis, or with thrombosis of the jugular system based on the International Statistical Classification of

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Chad A. Holder, D. Antonio Bell, Andrea L. Lundell, John L. Ulmer and Steven S. Glazier

D eep cerebral venous thrombosis represents a subset of cerebral venous thrombosis that is associated with a significantly worse clinical outcome than dural sinus thrombosis alone. 3 Although limited experience with treatment of dural sinus thrombosis by direct urokinase infusion has been described, 5, 6 our search of the literature showed no reports of selective catheterization and urokinase infusion into the straight sinus for treatment of acute straight sinus thrombus and deep cerebral venous thrombosis. This report describes such a case, which resulted

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Ali Chahlavi, Michael P. Steinmetz, Thomas J. Masaryk and Peter A. Rasmussen

C erebral venous thrombosis is relatively uncommon, with mortality rates ranging from 5 to 30%. 1 Cerebral venous thrombosis most often affects young and middle-aged patients and is more common in women than in men. 5, 28, 50 It is associated with hypercoagulable states secondary to dehydration, meningitis, pregnancy, sickle cell disease, oral contraceptive use, and numerous other conditions. Diagnosis may be difficult because of nonspecific signs and symptoms. This difficulty may lead to a significant delay in diagnosis, which directly affects prognosis