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Mitchel Seruya, Albert K. Oh, Gary F. Rogers, Michael J. Boyajian, John S. Myseros, Amanda L. Yaun and Robert F. Keating

O pen cranial remodeling procedures remain the standard treatment for craniosynostosis. One of the greatest concerns during these operations is blood loss, which can range from 20% to 500% of total blood volume as a result of the extensive exposure and bony osteotomies. 32 , 45 Moreover, these operations are routinely performed in infants with low circulating blood volumes, and even low levels of blood loss can result in life-threatening hypotension and cardiac arrest. 22 In a recent analysis of more than 8000 major craniofacial procedures, 50% of all

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Jennifer R. Voorhees, Aaron A. Cohen-Gadol, Edward R. Laws and Dennis D. Spencer

against blood loss from the brain, the silver clip. Because Cushing's techniques enabled him to treat many tumors directly, the majority of his work now involved direct contact with delicate brain tissue. Accepted mechanisms for controlling bleeding in general surgery, such as suturing or clamping, were not suitable for the delicate brain tissue or were too awkward for the small operative field. In this way, procedures became longer and more tedious, and hemostasis more important. The duration of the surgical procedures—extended numerous times to deal with hemostasis

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Christian Schneider, Ian Kamaly-Asl, Vijay Ramaswamy, Lucie Lafay-Cousin, Abhaya V. Kulkarni, James T. Rutka, Marc Remke, Daniel Coluccia, Uri Tabori, Cynthia Hawkins, Eric Bouffet and Michael D. Taylor

chemotherapy, it appeared that tumor vascularity was significantly reduced. Grosstotal resection seemed to be easier and blood loss less of a concern. 15 Histological assessment of the tumor tissue from these second resections showed fibrotic changes and a markedly decreased vascularity. 10 This empirical finding— also reported in the literature—eventually led to an institutional change in management, with the administration of ICE chemotherapy in a neoadjuvant fashion. 10 , 13 , 14 In 1999, the first patient underwent an intentional diagnostic biopsy with tumor resection

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Emma M. Sim, Matthew H. Claydon, Rhiannon M. Parker and Gregory M. Malham

common iliac artery. 1 , 3 , 5 , 7 , 8 , 10–13 , 16 To prevent iliac artery thrombosis, heparin can be administered when the retraction causes arterial obstruction. There is concern that this will increase the procedural blood loss. The aim of this study was to examine whether intraoperative heparin can be administered without increasing blood loss in anterior lumbar spine surgery. Methods Between January 2009 and June 2014, we undertook a prospective study of consecutive anterior approaches for lumbar spine surgery performed by a single vascular surgeon (M

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Michael Karsy, Brian Burnett, Antonio Di Ieva, Michael D. Cusimano and Randy L. Jensen

our methods for the measurement of tumor microvascularity with additional staining techniques and automated quantification methods that have not yet been previously explored in meningiomas. Using these methods, we test the hypothesis that tumor microvascularity is correlated with tumor size, estimated blood loss (EBL) during surgery, progression-free survival (PFS), and overall survival (OS) of patients with WHO Grade I meningiomas. Methods Patients Patient demographic data and tumor tissues were collected from 1996 to 2011 in an institutional review board

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Signe Elmose, Mikkel Ø. Andersen, Else Bay Andresen and Leah Yacat Carreon

, multilevel decompression and instrumented fusion). Various randomized controlled trials, systematic reviews, and meta-analyses have investigated the efficacy of using intravenous TXA during major spinal surgery, and they have shown a significant reduction in perioperative blood loss. 1–3 , 6 , 9–16 To our knowledge there are no studies of the effect of TXA on blood loss in minor lumbar surgery, and none of the existing studies assessed what effect the reduction of bleeding due to TXA administration has on the duration of surgery. The objective of this study is to

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Ole J. Kirkeby, Ingunn R. Rise, Lars Nordsletten, Sigmund Skjeldal and Cecilie Risøe

raised to approximately 80% of MAP, and all measurements were repeated before and after the withdrawal of 25% of the blood volume. The high ICP was stable for 5 minutes before the blood loss. Sources of Supplies and Equipment The model 900B servoventilator was manufactured by Siemens, Solna, Sweden; the pressure transducer, model AE 840, by Sensoner, Horten, Norway; and the pressure amplifier and chart recorder, model ES2000, by Gould, Cleveland, OH. Microspheres were supplied by New England Nuclear, Boston, MA. The infusion pump was manufactured by Braun Melsungen

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Mitchel Seruya, Albert K. Oh, Michael J. Boyajian, John S. Myseros, Amanda L. Yaun and Robert F. Keating

I ntraoperative blood loss remains one of the most significant concerns during open reconstruction for craniosynostosis. 35 In young infants with low circulating blood volume, even relatively small amounts of blood loss can represent a large proportion of total blood volume, potentially leading to life-threatening hypotension and cardiac arrest. 9 The degree of blood loss following open craniofacial repair continues to be debated, with numbers cited between 25% and 500% EBV. 13 Assessment of blood loss also differs, ranging from EBL recorded by the

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Ruben E. M. Hekster, Bartolomeo Matricali and Willem Luyendijk

in cases in which this is expected to be a problem. We have found that blood loss is almost negligible and the length of the operation much shorter when this procedure is used. We are presenting a case to demonstrate the simplicity of the procedure. Case Report A 39-year-old woman had since 1971 experienced twitching of the fingers of the right hand for several minutes. In June, 1973, she suddenly lost consciousness after a twitching episode. When she was seen in our department no neurological abnormalities were found. Common carotid angiography demonstrated

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Junichi Kushioka, Tomoya Yamashita, Shinya Okuda, Takafumi Maeno, Tomiya Matsumoto, Ryoji Yamasaki and Motoki Iwasaki

P osterior lumbar interbody fusion (PLIF) has resulted in satisfactory outcomes for the treatment of unstable lumbar degenerative disorders. In the last decade the number of patients who underwent PLIF significantly increased. 9 , 15 Conventional PLIF is not a minimally invasive procedure, and it is important to carefully monitor blood loss, especially from the epidural space. An increase in intraoperative blood loss may lead to hypotension, disturbance in oxygenation of organs, and difficulty visualizing the operative field for surgeons. Postoperative