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Praveen V. Mummaneni, John F. Burke, Andrew K. Chan, Julie Ann Sosa, Errol P. Lobo, Valli P. Mummaneni, Sheila Antrum, Sigurd H. Berven, Michael S. Conte, Sarah B. Doernberg, Andrew N. Goldberg, Christopher P. Hess, Steven W. Hetts, S. Andrew Josephson, Maureen P. Kohi, C. Benjamin Ma, Vaikom S. Mahadevan, Annette M. Molinaro, Andrew H. Murr, Sirisha Narayana, John P. Roberts, Marshall L. Stoller, Philip V. Theodosopoulos, Thomas P. Vail, Sandra Wienholz, Michael A. Gropper, Adrienne Green, and Mitchel S. Berger

H ealthcare providers and hospitals face unprecedented challenges during the COVID-19 pandemic. 1 , 2 Providers at tertiary-care hospitals in severely affected areas around the world (including those from China, 2 Taiwan, 3 Singapore, 4 and Italy 5 , 6 ) have published institutional protocols to help aid healthcare workers in this crisis. 7–9 As the pandemic has now spread to the US, 10 , 11 it is imperative to adapt these algorithms to the US healthcare setting. 12 The University of California, San Francisco (UCSF) is a quaternary-care academic hospital

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Christian Hoelscher, Ahmad Sweid, Ritam Ghosh, Fadi Al Saiegh, Kavantissa M. Keppetipola, Christopher J. Farrell, Jack Jallo, Pascal Jabbour, Stavropoula Tjoumakaris, M. Reid Gooch, Robert H. Rosenwasser, and Syed O. Shah

O n March 11, 2020, the World Health Organization declared that coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is a pandemic. 1 The virus has a high reproduction number (2.0–2.5) allowing it to infect a large number of the world population. 2 The primary organ affected is the respiratory system; however, neurological manifestations have been reported. 3 Herein, we describe a case of COVID-19 infection with pulmonary manifestations and encephalopathy due to cerebral venous

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Carmen R. Holmes, Giuseppe Lanzino, and Kelly D. Flemming

Very little has been published regarding the influence of coronavirus disease 19 (COVID-19) on cavernous malformation (CM) formation and hemorrhage. A recent, small study suggests a possible increased risk of CM hemorrhage in patients who develop COVID-19. 1 To date, there have been no reported cases of de novo CM formation in the setting of COVID-19. Illustrative Case In the summer of 2020, our patient, a 31-year-old female, developed mild galactorrhea and was subsequently found to have mildly elevated prolactin level. A brain MRI with dedicated

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Chase H. Foster, Anthony J. Vargas, Elizabeth Wells, Robert F. Keating, and Suresh N. Magge

A growing body of evidence indicates an association between coronavirus disease 2019 (COVID-19)—the pandemic illness caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2)—and cerebrovascular disease. Since the emergence of the disease in December 2019, several case series have described an observed predilection for thrombogenicity, 1 vasculopathy, 2 and strokes, 3 primarily in adult patients with COVID-19. In fact, studies have overwhelmingly found advanced age to be an independent increased risk factor for COVID-19–related stroke (CoV

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Chinmaya Dash, Tejas Venkataram, Nishant Goyal, Jitender Chaturvedi, Amol Raheja, Raghav Singla, Jayesh Sardhara, and Ravi Gupta

T he coronavirus disease of 2019 (COVID-19) is a global pandemic that has had a severe impact on healthcare globally. The healthcare infrastructure has been made to adapt to this medical crisis globally with modifications in our daily practice. Despite the country’s huge population and limited healthcare resources, India has managed to keep the total count of COVID-19 patients to fewer than 200,000 at the time of writing this article (June 3, 2020). 1 However, the country needs to prepare itself for the greater challenges ahead as the number of cases are

Open access

Nathaniel R. Ellens and Howard J. Silberstein

In March 2020, SARS-CoV2 (coronavirus disease 2019 [COVID-19]) was declared a global pandemic. 1 Since the initial outbreak, the virus has spread throughout the world with more than 65 million confirmed cases and 1.5 million deaths reported worldwide. 2 This virus is known to cause more severe symptoms in adults than in children, and common symptoms include fever, cough, shortness of breath, fatigue, myalgias, vomiting, diarrhea, and anosmia. 3–5 In the adult population, there is also an increased association between the COVID-19 virus and

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Johnson Ku, Chieh-Yi Chen, Jason Ku, Hsuan-Kan Chang, Jau-Ching Wu, and Yu-Shu Yen

Since its outbreak, coronavirus disease 2019 (COVID-19) has resulted in more than 171 million confirmed cases and caused more than 3.7 million deaths worldwide. 1 Acute respiratory distress syndrome and respiratory failure develop in many patients with severe COVID-19. Additionally, multiple organ failure, such as acute cardiac, kidney, and liver injury, in addition to cardiac arrhythmias, rhabdomyolysis, coagulopathy, and shock, may result from COVID-19. 2 Besides acute respiratory syndrome, viral infection may also lead to serious neurological

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Zhengyu Lin, Chencheng Zhang, Yingying Zhang, Lulin Dai, Valerie Voon, Dianyou Li, and Bomin Sun

D eep brain stimulation (DBS) is a neurosurgical treatment option for severe and refractory cases of movement disorders and certain psychiatric disorders. Postoperative programming is a critical part of case management for patients who have undergone DBS surgery. However, the ongoing coronavirus disease 2019 (COVID-19) pandemic has exposed major weaknesses in the delivery of medical care to patients in whom DBS devices have been implanted. Specifically, many patients who had undergone DBS surgery were unable to attend initial routine postoperative DBS

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Pierre-Olivier Champagne, Michael M. McDowell, Eric W. Wang, Carl H. Snyderman, Georgios A. Zenonos, and Paul A. Gardner

a high mortality rate, especially in the elderly or those with comorbidities. 3 First reported from Wuhan, China, on December 31, 2019 ( ), the virus has spread rapidly and become a global pandemic. There have been anecdotal reports of the spread of coronavirus disease 2019 (COVID-19; the disease caused by the novel coronavirus) to medical professionals during endonasal surgery, and surgical societies have developed guidelines for surgery during the pandemic. 4 However, there remains a dearth of

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Sushanta K. Sahoo, Sivashanmugam Dhandapani, Apinderpreet Singh, Chandrashekhar Gendle, Madhivanan Karthigeyan, Pravin Salunke, Ashish Aggarwal, Navneet Singla, Raghav Singla, Manjul Tripathi, Rajesh Chhabra, Sandeep Mohindra, Manoj Kumar Tewari, Manju Mohanty, Hemant Bhagat, Arunaloke Chakrabarti, and Sunil Kumar Gupta

C ovid-19 has caused a paradigm shift in the medical and surgical care of patients. Governments in many countries have enforced lockdowns to restrict the spread of infection. Still, the number of COVID-19 cases is on the rise in many countries, including India. 1 Medical facilities have been diverted toward managing the unprecedented situation brought about by the COVID-19 pandemic. Almost all hospitals worldwide were forced to suspend their elective surgeries and formulate new guidelines for patient admission, taking into consideration the level of the