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Rafael De la Garza-Ramos, Mario Benvenutti-Regato and Enrique Caro-Osorio

spinal oncology. Treatments involving wild-type neurofibromatosis 2 gene insertion, oncolytic viruses, and transfer of gene-silencing ribonucleic acid have all shown promising results in vitro for meningiomas. 37 Stereotactic body radiotherapy (radiosurgery) has been used as a first-line treatment for metastatic lesions, after failure of conventional radiotherapy, after separation surgery, and as first-line treatment for primary tumors and has shown promising results in each approach. 17 Recently, proton-beam therapy has gained attention because it can deliver high

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Aditya V. Karhade, Viren S. Vasudeva, Hormuzdiyar H. Dasenbrock, Yi Lu, William B. Gormley, Michael W. Groff, John H. Chi and Timothy R. Smith

case for extended prophylaxis . Ann Surg 254 : 131 – 137 , 2011 65 Mesfin A , Buchowski JM , Gokaslan ZL , Bird JE : Management of metastatic cervical spine tumors . J Am Acad Orthop Surg 23 : 38 – 46 , 2015 66 Moussazadeh N , Laufer I , Yamada Y , Bilsky MH : Separation surgery for spinal metastases: effect of spinal radiosurgery on surgical treatment goals . Cancer Contr 21 : 168 – 174 , 2014 67 Mukherjee D , Chaichana KL , Gokaslan ZL , Aaronson O , Cheng JS , McGirt MJ : Survival of patients with

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Roxana M. Grasu, Juan P. Cata, Anh Q. Dang, Claudio E. Tatsui, Laurence D. Rhines, Katherine B. Hagan, Shreyas Bhavsar, Sally R. Raty, Radha Arunkumar, Yury Potylchansky, Ian Lipski, Benjamin A. Arnold, Thomas M. McHugh, Justin E. Bird, Andrea Rodriguez-Restrepo, Mike Hernandez and Keyuri U. Popat

, Song Y , Yang SY , Park SJ , Kwak YL : Effect of ketamine as an adjunct to intravenous patient-controlled analgesia, in patients at high risk of postoperative nausea and vomiting undergoing lumbar spinal surgery . Br J Anaesth 111 : 630 – 635 , 2013 10.1093/bja/aet192 23744819 38 Tatsui CE , Stafford RJ , Li J , Sellin JN , Amini B , Rao G , : Utilization of laser interstitial thermotherapy guided by real-time thermal MRI as an alternative to separation surgery in the management of spinal metastasis . J Neurosurg Spine 23 : 400

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Dara Bakar, Joseph E. Tanenbaum, Kevin Phan, Vincent J. Alentado, Michael P. Steinmetz, Edward C. Benzel and Thomas E. Mroz

-dose single-fraction radiosurgery for spine metastases . J Neurosurg Spine 13 : 87 – 93 , 2010 26 Moussazadeh N , Laufer I , Yamada Y , Bilsky MH : Separation surgery for spinal metastases: effect of spinal radiosurgery on surgical treatment goals . Cancer Contr 21 : 168 – 174 , 2014 27 Ortiz Gómez JA : The incidence of vertebral body metastases . Int Orthop 19 : 309 – 311 , 1995 28 Padalkar P , Tow B : Predictors of survival in surgically treated patients of spinal metastasis . Indian J Orthop 45 : 307 – 313 , 2011 29 Park JH

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San Diego, CA • April 13–17, 2019

in the lumbar spine. Conclusions: Clinical data from the first 100 patients demonstrate that sLITT is a safe and viable ablative treatment options for patients with ESCC, and may be considered an alternative to separation surgery for carefully selected patients with lesions in the thoracic spine. 223. Improvement in Sexual Function Following Degenerative Lumbar Spondylolisthesis Surgery Andrew K. Chan, MD (San Francisco, CA); Praveen Mummaneni, MD; Leslie Robinson; Kai-Ming Fu, MD, PhD; Paul Park, MD; Mohamad Bydon, MD; Mark Shaffrey, MD; Michael Wang, MD

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Miami, Florida • March 14–17, 2019

.3%, with 3 patients developing procedure-related neurological deficits, but there were no cases of radiation myelopathy. There were no differences in local control if a patient had anterior column reconstruction or not. Conclusion SRS is an effective treatment modality following all types of surgery for metastases, not just separation surgery. SRS should be considered in the post-operative management for spinal metastases given the low side effect profile and low complications. 267 Penetrating Spinal Cord Injury in Civilians: Analysis of a National Database Mauricio J