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Bror A. Rexed and K. Gunnar Wennström

I n Preliminary communications in 1947 and 1949 Rexed 12, 13 described certain pathological changes in human nerve-root pouches. The lesion consists of pathological thickening and proliferation of the arachnoidea, in extreme cases deforming and compressing the nerve roots, and often associated with cystic formations in and about the root bundles. The lesion is common, and is not associated with syphilis, tuberculosis, or other specific infections involving the central nervous system. By means of roentgenological studies on cadavers, Lindblom 7 in 1948

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William Henry Hudson, M.D.

Itinerant Neurosurgeon 1862–1917

Edgar F. Fincher

. Sea-sickness. Its cause, nature, and prevention without medicine or change in diet. A scientific and practical solution of the problem. Boston : S. E. Cassino & Co. , 1883 , 147 pp. Hudson , W. H. Sea-sickness. Its cause, nature, and prevention without medicine or change in diet. A scientific and practical solution of the problem. Boston: S. E. Cassino & Co. , 1883, 147 pp. 2. Hudson , W. H. Tuberculosis as an infectious bacilliary disease, and its relation to hygiene. Trans. med. Ass. Ala. , 1890 , 353 – 374

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W. Eugene Stern and Paul H. Crandall

patients had undergone previous disc surgery. The authors described a recent history of infection in over half of their cases; the acute illness was characterized by fever, pain in the back, local spasm of muscles and tenderness, and minimal irritation of the nervous system. The condition responded to rest. Early roentgenograms were normal, but subsequent radiological study of their cases revealed thinning of the disc, proliferation, and eventual fusion. These authors discussed the differential diagnosis, including tuberculosis, typhoid fever, and brucellosis. In

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Shigetsugu Katsura, Jiro Suzuki and Tokuo Wada

. This field should be explored further. Operative cases will increase gradually with development of anticancer substances. Most of our granulomas are tuberculomas. Previously, Nakata 19 reported an incidence of 6 per cent, which was much higher than that in other countries. In the present series, it decreased to 3.1 per cent, and a further decrease is now following the recent progress of antituberculous therapy. The decrease in incidence of tuberculoma runs parallel to the decrease in the number of cases of pulmonary tuberculosis. In Japan, intracranial tumors

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Bronson S. Ray

. Following operation their fasting blood sugar returned to normal and insulin was no longer required. A sound basis for recognizing the influence of the pituitary in diabetes mellitus exists in Houssay's experimental demonstration 6 that diabetes secondary to pancreatectomy is ameliorated by extirpation of the anterior pituitary. Occasionally, the “Houssay phenomenon” has been observed to occur in human diabetics from a variety of pituitary abnormalities including hemorrhage, infarction, tuberculosis and metastatic neoplasms. Additional evidence of the relationship of

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Thomas R. Hunt Jr., Charles M. Poser and William P. Williamson

interest. The lymphocytic pleocytosis, low sugar, and normal protein are typical of the chronic (tuberculosis and Cryptococcus) and aseptic meningitides. Berg 1 has recently reviewed the subject of decreased sugar in the spinal fluid (hypoglycorrhachia). He found that it was frequently associated with malignancies involving the central nervous system, particularly diffuse carcinomatosis or gliomatosis of the leptomeninges. He concluded that the presence of hypoglycorrhachia associated with signs of increased intracranial pressure, meningeal irritation, organic mental

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Tuberculous Optic Neuritis

An Experimental Study

A. J. Behar, A. J. Beller and S. Feldman

animals, comprising the first group, were sensitized with killed bovine tubercle bacilli; after a positive tuberculin test was found in all of them, each received an intracisternal injection of approximately 100,000 tubercle bacilli of the Myco. tuberculosis bovis strain, suspended in 0.2 ml. of physiological saline, under sterile conditions. The culture used was sensitive to concentrations of 0.5 mg. per ml. of streptomycin and isoniazid. The second group of 14 animals was not sensitized with killed tubercle bacilli but otherwise was treated in the same way

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Ralph B. Cloward

removal of the vertebra have led to its use in other pathological conditions: (1) comminuted compression fractures of a single cervical vertebral body has been treated by removing most of the bone fragments together with the adjacent intervertebral disks and filling the defect with a large bone graft; 6 (2) infections such as osteomyelitis, tuberculosis, granulomas, etc. have also been treated by radical removal of diseased bone and replacing it with a bone graft. Excellent results have been obtained in 6 patients with Pott's paraplegias from thoracic lesions, in which

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Tung Hui Lin

Since the report of Serre of Paris in 1830, the rare incidence of tuberculoma of the spinal cord has been commented on by various authors. Jennings 9 found only 1 spinal cord tuberculoma among 5,344 patients with tuberculosis of the lung. Jaffé and Schultz 8 disclosed 1 spinal cord tuberculoma in 7,000 autopsies contrasted with 48 cerebral tuberculomas in the same group. In Kernohan's statistics the ratio of spinal cord tuberculoma to other spinal cord tumors was 1:48. Thalhimer and Hassin 15 collected 84 cases but only 67 were definitely documented. They

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Robert Edgar and Maitland Baldwin

of the skull revealed a calcified lesion in the right parietal area. Clinical history, Mantoux skin test, roentgenograms of the chest, cervical-node biopsy, gastric and cerebrospinal fluid cultures for A.F.B. and guinea pig innoculations were all negative for tuberculosis. Roentgenograms of the skull taken in June 1946 and in April 1951 were compared and revealed increased density of calcification but no increase in size of the lesion. Electroencephalographic abnormalities were localized to the right parietal area. At operation a yellow-white, hard circular mass